Psycho-Babble Medication Thread 527771

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cool AP binding chart

Posted by linkadge on July 14, 2005, at 21:01:10

http://www.psychiatryinpractice.com/psychiatryinpractice/ImageBankView.aspx?contentId=10

 

Re: cool AP binding chart

Posted by linkadge on July 14, 2005, at 21:06:00

In reply to cool AP binding chart, posted by linkadge on July 14, 2005, at 21:01:10

Mind you, this link is the biggest waste of time.

http://www.psychiatryinpractice.com/psychiatryinpractice/ImageBankView.aspx?contentId=356

Linkadge

 

Re: cool AP binding chart

Posted by sleepygirl on July 14, 2005, at 21:48:59

In reply to Re: cool AP binding chart, posted by linkadge on July 14, 2005, at 21:06:00

THAT was a very interesting picture!! Thanks for the pie chart links, good for those of us too lazy to do all the neurotransmitter binding site research stuff :-)
-sleepy

 

Re: cool AP binding chart

Posted by sleepygirl on July 14, 2005, at 21:50:09

In reply to cool AP binding chart, posted by linkadge on July 14, 2005, at 21:01:10

Holy H1 receptor on Seroquel!!! Is that the one that makes you tired?!! Holy crap! no wonder...

 

Re: cool AP binding chart

Posted by sleepygirl on July 14, 2005, at 21:54:52

In reply to cool AP binding chart, posted by linkadge on July 14, 2005, at 21:01:10

OK sorry for all the stalking... but H is for histamine, 5HT is serotonin, D is for dopamine right?? but what's the straight A1, A2 and the M if you don't mind?

 

Re: cool AP binding chart

Posted by yxibow on July 15, 2005, at 1:58:44

In reply to Re: cool AP binding chart, posted by sleepygirl on July 14, 2005, at 21:54:52

> OK sorry for all the stalking... but H is for histamine, 5HT is serotonin, D is for dopamine right?? but what's the straight A1, A2 and the M if you don't mind?


I believe A1 is the alpha-adrenergic receptor that is responsible for orthostatic hypotension (low blood pressure) in Seroquel

The "M" muscarinic receptor profiles are more complicated, but are named for the "fly agaric mushroom" Amanita muscaria; antagonists are anticholinergics.

I'm sure ed_uk could add more...

 

Re: cool AP binding chart

Posted by xbunny on July 15, 2005, at 4:36:59

In reply to cool AP binding chart, posted by linkadge on July 14, 2005, at 21:01:10

> http://www.psychiatryinpractice.com/psychiatryinpractice/ImageBankView.aspx?contentId=10

thats pretty cool but half of olanzapine seems to be missing, or is it all M?

 

Re: cool AP binding chart

Posted by rjlockhart98 on July 15, 2005, at 9:36:16

In reply to Re: cool AP binding chart, posted by xbunny on July 15, 2005, at 4:36:59

Haldol seems to be the most "dopamine" blocking.

Is there a diffrence in the effects on how your perception is changed by which transmitter is more effected?

What about Thorazine?

 

Re: cool AP binding chart

Posted by yxibow on July 15, 2005, at 15:23:02

In reply to Re: cool AP binding chart, posted by rjlockhart98 on July 15, 2005, at 9:36:16

> Haldol seems to be the most "dopamine" blocking.
>

...and among ones that causes the most EPS/TD as well... Haldol is very cheap, but I think more "kinder, gentler" atypicals should be used before resorting to it unless the disorder in hand is very uncontrollable

> Is there a diffrence in the effects on how your perception is changed by which transmitter is more effected?
>
> What about Thorazine?

the chart [fig 18.6] (I was trying to find another similar one that included more modern medications)
shows relative binding of certain older neuroleptics


http://www.chemistry.emory.edu/justice/chem190j/pharmaco.htm


 

thanks!! (nm) yxibow

Posted by sleepygirl on July 15, 2005, at 20:40:51

In reply to Re: cool AP binding chart, posted by yxibow on July 15, 2005, at 1:58:44


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