Psycho-Babble Medication Thread 426686

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MAOI and beta blockers ?!

Posted by Ted_Brosnan on December 9, 2004, at 10:03:31

Hi,

My psychiatrist told me on tuesday that he would rx a MOAI along with a beta blocker. That I could take in a case of hypertensive crisis.

Would I really have time to take a beta blocker, and that it would be rapidly absorbed so it would help?!

I really must ask my doctor for information about hypertensive cisis, how it feels like?!

 

Re: MAOI and beta blockers ?!

Posted by ed_uk on December 9, 2004, at 10:45:19

In reply to MAOI and beta blockers ?!, posted by Ted_Brosnan on December 9, 2004, at 10:03:31

Hi Ted,

Most beta blockers would not be suitable treatments for a hypertensive crisis. Non-selective beta-blokers such as propranolol might possibly aggravate a hypertensive crisis by blocking beta-2 receptors, allowing 'unopposed' alpha-1 mediated vasoconstriction. The only beta-blocker which might be helful is labetalol (Trandate) because it is also an alpha blocker.

Nifedipine and chlorpromazine are the usual emergency meds to give to people receiving MAOIs. Phentolamine injection can be used in hospital.

Here are some hypertensive crisis symptoms. The list is taken from rxlist.com.

severe headache, palpitations, neck stiffness or soreness, nausea, vomiting, sweating (sometimes with fever and sometimes with cold, clammy skin), dilated pupils, and photophobia (light causes discomfort). Either tachycardia (rapid heart rate) or bradycardia (slow heart rate) may be present and can be associated with chest pain.

Some of the above symptoms are also common side effects of MAOIs such as nausea and headache. Hypertensive crises tend to cause much more severe symptoms.

Regards,
Ed.

 

Re: MAOI and beta blockers ?!

Posted by djmmm on December 9, 2004, at 18:13:44

In reply to Re: MAOI and beta blockers ?!, posted by ed_uk on December 9, 2004, at 10:45:19

Inderal is just as effective as other treatments for hypertensive crisis...however, other meds work more rapidly. Propranolol is used in hospitals (as is diazepam and nifedipine) via sublingual administration.

 

Re: MAOI and beta blockers ?!

Posted by ed_uk on December 10, 2004, at 7:50:05

In reply to Re: MAOI and beta blockers ?!, posted by djmmm on December 9, 2004, at 18:13:44

I still don't think that propranolol is a suitable treatment. A lot of treatments used in hospital are inappropriate. A vasodilator would be more suitable.

Ed.


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