Psycho-Babble Medication Thread 367484

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How bad/What is Serotonin Syndrome?

Posted by 1980Monroe on July 18, 2004, at 18:44:30

Is it something to just blow off and wait till its over, or is it a serious condition.

I'm would like to hear from people who are wise on this sort of Subject.

 

Re: How bad/What is Serotonin Syndrome?

Posted by linkadge on July 19, 2004, at 13:48:12

In reply to How bad/What is Serotonin Syndrome?, posted by 1980Monroe on July 18, 2004, at 18:44:30

It can range from mild to life threatening. I would get a list of the symptoms from the internet somewhere if you are concerned. I have had a moderate hit of SS, and it would have been a good idea for me to have gone to the hospital.


Linkadge

 

Re: How bad/What is Serotonin Syndrome?

Posted by SLS on July 19, 2004, at 14:00:48

In reply to How bad/What is Serotonin Syndrome?, posted by 1980Monroe on July 18, 2004, at 18:44:30

Serotonin Syndromes

1. Serotonin Syndrome


The symptoms of serotonin syndrome include the following:

Mental status changes
Confusion (51%)
Agitation (34%)
Hypomania (21%)
Anxiety (15%)
Coma (29%)

Cardiovascular
Sinus tachycardia (36%)
Hypertension (35%)
Hypotension (15%)

Gastrointestinal
Nausea (23%)
Diarrhea (8%)
Abdominal pain (4%)
Salivation (2%)

Motor Abnormalities
Myoclonus (58%)
Hyperreflexia (52%)
Muscle rigidity (51%)
Restlessness (48%)
Tremor (43%)
Ataxia/incoordination (40%)
Shivering (26%)
Nystagmus (15%)
Seizures (12%)

Other
Diaphoresis (45%)
Unreactive pupils (20%)
Tachypnea (26%)
Hyperpyrexia


 

Re: How bad/What is Serotonin Syndrome?

Posted by 1980Monroe on July 19, 2004, at 21:26:33

In reply to Re: How bad/What is Serotonin Syndrome?, posted by SLS on July 19, 2004, at 14:00:48

Thanks SLS.

Now i know if i have it, not that i plan to ever have it........

But this helps.

Matt

 

Re: How bad/What is Serotonin Syndrome? » 1980Monroe

Posted by jerrympls on July 20, 2004, at 23:32:26

In reply to How bad/What is Serotonin Syndrome?, posted by 1980Monroe on July 18, 2004, at 18:44:30

> Is it something to just blow off and wait till its over, or is it a serious condition.
>
> I'm would like to hear from people who are wise on this sort of Subject.

I suffered a full-blown case of serotonin syndrome last year while on Nardil. I accidentally took some Nyquil to help me sleep. At first I thought I was having a hypertensive reaction, but the docs in the ICU told me otherwise.

Nyquil has dextromethorphan which is in most OTC cough meds as a supressant. It also blocks reuptake of serotontin and when mixed with a potent med like the MAOI Nardil - it can have dangerous outcomes.

15 mins after I took a couple teaspoons of the Nyquil, I started to shake uncontrollably and it continued to get worse - I don't know how to explain the serverity - but I can say I didn't know the human body had such power to shake its self. Then I started sweating - pouring sweat. I started to become really confused and scared so I crawled to the phone and dialed 911. Luckily they came within 5 mins. They had to strap me down in the ambulance so I wouldn't shake out of the gurney.

I was in and out of consciousness and next thing I know I'm in the ICU with doctors all around me. I heard them say to give me periactin (an old antihistamine that blocks release of serotonin) and ativan. I finally started to calm down a bit but was still having terrible bouts of severe shaking. The Periactin made me sleepy. Then I heard the docs say they were worried about kidney failure.

I was kept overnight and had to have my urine measured to make sure my kidneys didn't give out.

LUCKILY I was ok the next day and was able to go home.

Be careful of the serotonin syndrome - it was one horrifying situation for me.

Jerry

 

Re: How bad/What is Serotonin Syndrome?

Posted by 1980Monroe on July 21, 2004, at 15:06:11

In reply to Re: How bad/What is Serotonin Syndrome? » 1980Monroe, posted by jerrympls on July 20, 2004, at 23:32:26

Wow, guess it isnt something you just wait to wear off of, sounds similar to a convultion. Thanks Jerry

I always wanted to know what an experince of SS would be like.


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