Psycho-Babble Medication Thread 350183

Shown: posts 1 to 15 of 15. This is the beginning of the thread.

 

Adrenal exhaustion - MAOIs?

Posted by Maxime on May 24, 2004, at 15:04:14

Does anyone know if MAOIs, specifically Parnate can cause Adrenal exhaustion?

I am on 80 mg of Parnate and I am so tired throughout the day, especially in the afternoon.

Anyone else experience this?

Anyone have any answers?

Maxime

 

Re: Adrenal exhaustion - MAOIs? Maxime

Posted by Ilene on May 24, 2004, at 17:32:37

In reply to Adrenal exhaustion - MAOIs?, posted by Maxime on May 24, 2004, at 15:04:14

5{e know if MAOIs, specifically Parnate can cause Adrenal exhaustion?
>
> I am on 80 mg of Parnate and I am so tired throughout the day, especially in the afternoon.
>
> Anyone else experience this?
>
> Anyone have any answers?
>
> Maxime

Not as far as I know. I have chronic fatigue syndrome, which is related to problems w/ the HPA axis (hypothalamus-pituitary-adrenal). My current internist understands cfs as well as anyone. He says one of my problems is low adrenal activity. He hasn't said anything about MAOIs (I take Marplan) affecting the adrenals.

There are lots of reasons why you could be tired during the afternoon that have nothing to do with adrenal exhaustion.

I.

 

Re: Adrenal exhaustion - MAOIs?

Posted by djmmm on May 24, 2004, at 19:11:33

In reply to Adrenal exhaustion - MAOIs?, posted by Maxime on May 24, 2004, at 15:04:14

> Does anyone know if MAOIs, specifically Parnate can cause Adrenal exhaustion?
>
> I am on 80 mg of Parnate and I am so tired throughout the day, especially in the afternoon.
>
> Anyone else experience this?
>
> Anyone have any answers?
>
> Maxime

It is most likely due to the increased amount of serotonin

 

Re: Adrenal exhaustion - MAOIs?

Posted by Maxime on May 24, 2004, at 20:06:58

In reply to Adrenal exhaustion - MAOIs?, posted by Maxime on May 24, 2004, at 15:04:14

Maybe I should have be more specific.

I have hypothroidism and take Synthroid. My levels are supposedly alright now and yet I get an overwhelming exhaustion. Not just tired. It's interfering with my work. My endocrinologist doesn't think it is necessary to test my adrenals.

3 weeks ago my pdoc put me on cortisone for 2 weeks to see if that would help with the exhaustion and break the depression. By the second week I did feel better. When the two weeks was over I CRASHED big time.

I had my blood checked and everything is fine.

I'm never going to feel good. I want to give up.

MAxime

 

Re: Adrenal exhaustion - MAOIs? Maxime

Posted by Questionmark on May 25, 2004, at 1:25:33

In reply to Re: Adrenal exhaustion - MAOIs?, posted by Maxime on May 24, 2004, at 20:06:58

Yeah, Parnate can do this pretty badly sometimes, for some reason. i'm not sure why. i think it might be partly due to acute alpha-1 adrenergic agonism, or maybe a result of some adaptation of dopamine receptors after sustained stimulation. i really don't know though. i've been quite curious about this myself. i really don't believe it's from any serotonin agonism, however (one of the few times i remember finding myself disagree with djmmm).
Hopefully it's just temporary though. i think that is often the case, if i remember correctly.


> Maybe I should have be more specific.
>
> I have hypothroidism and take Synthroid. My levels are supposedly alright now and yet I get an overwhelming exhaustion. Not just tired. It's interfering with my work. My endocrinologist doesn't think it is necessary to test my adrenals.
>
> 3 weeks ago my pdoc put me on cortisone for 2 weeks to see if that would help with the exhaustion and break the depression. By the second week I did feel better. When the two weeks was over I CRASHED big time.
>
> I had my blood checked and everything is fine.
>
> I'm never going to feel good. I want to give up.
>
> MAxime

 

Re: Adrenal exhaustion - MAOIs?

Posted by Maxime on May 25, 2004, at 21:27:23

In reply to Re: Adrenal exhaustion - MAOIs? Maxime, posted by Questionmark on May 25, 2004, at 1:25:33

Thanks. Unfortunately it has been the case all along. Sigh.

I finally got my pdoc to admit to something today. That I will never feel "normal". In other words, I am one of those people that will have to live with depression to some degree for the rest of my life. Not I that I wanted to hear that, or that he was giving up on me, but he was being honest. And I know many of you will say that there is stuff coming out all the time etc. BUt I have been battling this forever.

Maxime

> Yeah, Parnate can do this pretty badly sometimes, for some reason. i'm not sure why. i think it might be partly due to acute alpha-1 adrenergic agonism, or maybe a result of some adaptation of dopamine receptors after sustained stimulation. i really don't know though. i've been quite curious about this myself. i really don't believe it's from any serotonin agonism, however (one of the few times i remember finding myself disagree with djmmm).
> Hopefully it's just temporary though. i think that is often the case, if i remember correctly.
>
>
> > Maybe I should have be more specific.
> >
> > I have hypothroidism and take Synthroid. My levels are supposedly alright now and yet I get an overwhelming exhaustion. Not just tired. It's interfering with my work. My endocrinologist doesn't think it is necessary to test my adrenals.
> >
> > 3 weeks ago my pdoc put me on cortisone for 2 weeks to see if that would help with the exhaustion and break the depression. By the second week I did feel better. When the two weeks was over I CRASHED big time.
> >
> > I had my blood checked and everything is fine.
> >
> > I'm never going to feel good. I want to give up.
> >
> > MAxime
>
>

 

Re: Adrenal exhaustion - MAOIs? Maxime

Posted by harryp on May 25, 2004, at 22:14:41

In reply to Re: Adrenal exhaustion - MAOIs?, posted by Maxime on May 25, 2004, at 21:27:23

I too have chronic depression, and take Parnate. I wanted to let you know that I experienced very noticeable fatigue the first few weeks on Parnate. It went away entirely a few weeks after I stabilized my dose, and I've had more energy than usual since.

Fatigue is a well known side-effect from Parnate. It usually, though not always, goes away with time. Don't give up until at least a few weeks have passed with no improvement after you settle on a dosage.

Hope this helps.

 

Re: Adrenal exhaustion - MAOIs? Maxime

Posted by Ilene on May 26, 2004, at 7:11:07

In reply to Re: Adrenal exhaustion - MAOIs?, posted by Maxime on May 25, 2004, at 21:27:23

> Thanks. Unfortunately it has been the case all along. Sigh.
>
> I finally got my pdoc to admit to something today. That I will never feel "normal". In other words, I am one of those people that will have to live with depression to some degree for the rest of my life. Not I that I wanted to hear that, or that he was giving up on me, but he was being honest. And I know many of you will say that there is stuff coming out all the time etc. BUt I have been battling this forever.
>
> Maxime
>

Aaaahhhhgggrrr. My pdoc said the same thing to me. She was not exactly correct. I can't say I feel "normal", but the degree of depression I feel now is so far diminished that I'm at least within shouting distance of normal. I don't know if I'm going to continue to get better, or whether this is the high point of my life, or what, but if your doctor can predict the future, s/he ought to be playing the stock market.

What did it for me was augmentation with Cytomel (T3 thyroid hormone). I spent months talking my pdoc into trying it, because I'm not clinically hypothyroid. I know many other people have tried it without success, but my point is that sometimes you have to experiment with less-proven remedies.

I.

 

Cold Heartless Psychiatrists (some not all)

Posted by Questionmark on May 28, 2004, at 17:27:21

In reply to Re: Adrenal exhaustion - MAOIs? Maxime, posted by Ilene on May 26, 2004, at 7:11:07

> > Thanks. Unfortunately it has been the case all along. Sigh.
> >
> > I finally got my pdoc to admit to something today. That I will never feel "normal". In other words, I am one of those people that will have to live with depression to some degree for the rest of my life. Not I that I wanted to hear that, or that he was giving up on me, but he was being honest. And I know many of you will say that there is stuff coming out all the time etc. BUt I have been battling this forever.
> >
> > Maxime
> >
>
> Aaaahhhhgggrrr. My pdoc said the same thing to me. She was not exactly correct. I can't say I feel "normal", but the degree of depression I feel now is so far diminished that I'm at least within shouting distance of normal. I don't know if I'm going to continue to get better, or whether this is the high point of my life, or what, but if your doctor can predict the future, s/he ought to be playing the stock market.
>
> What did it for me was augmentation with Cytomel (T3 thyroid hormone). I spent months talking my pdoc into trying it, because I'm not clinically hypothyroid. I know many other people have tried it without success, but my point is that sometimes you have to experiment with less-proven remedies.
>
> I.

That's freaking B.S.!!! i can't believe how many times i've heard/read somebody say that his/her dr said that to them. What EFFING right does he/she have to say something like that???!!!!! Soihja;sdlkfh!!!!!!
If another pdoc ever says something like that to someone, you should just reply, "Well in that case i should just spit in your face and crap on your desk and slap you silly." What are they gonna do-- make you hate your life??
Sorry. i'm just so sick of hearing about this kind of s**t. No other field has had the lack of ethical responsibility, client (patient) concern & compassion, oversight, and AHHHH idontknowwhatelse ... as the field of psychiatry. From lobotomies and ineffectually developed ECT to overdosing of antipsychotics and the modern-day reliance on newer drugs, and everything else-- all the many many, more minor, yet-still-significant ineptitudes-- psychiatry, although immensely helpful, has caused an extraordinary amount of unrestituted damage and suffering. And more than anything else, in my opinion, it is because of arrogance and overconfidence (often coupled with extreme voids in empathy and compassion) that this occurs.

 

Re: Cold Heartless Psychiatrists (some not all) Questionmark

Posted by almondjoy on May 29, 2004, at 23:06:34

In reply to Cold Heartless Psychiatrists (some not all), posted by Questionmark on May 28, 2004, at 17:27:21

> > > I finally got my pdoc to admit to something today. That I will never feel "normal".
> > >
> > > Maxime
> > >
> >
> > Aaaahhhhgggrrr. My pdoc said the same thing to me.

> Sorry. i'm just so sick of hearing about this kind of s**t. No other field has had the lack of ethical responsibility, client (patient) concern & compassion, oversight, and AHHHH idontknowwhatelse ... as the field of psychiatry. From lobotomies and ineffectually developed ECT to overdosing of antipsychotics and the modern-day reliance on newer drugs, and everything else-- all the many many, more minor, yet-still-significant ineptitudes-- psychiatry, although immensely helpful, has caused an extraordinary amount of unrestituted damage and suffering. And more than anything else, in my opinion, it is because of arrogance and overconfidence (often coupled with extreme voids in empathy and compassion) that this occurs.

I totally agree with alot of what you said, but I was grateful to hear my pdoc say I will probably be struggling with depression for the rest of my life. Even if it doesn't turn out that way (hopefully its not!!!) I felt my seemingly endless resistence against the darkest oppressions was acknowledged, and he wasn't being sickeningly optimistic...if it's true, like with any other medical problem, I want my doc to tell me straight. a chemical imbalance in my brain isn't going to fix itself...terminal cancer usu doesn't just go away...amputated limbs don't grow back...though i hate the field of psychiatry in general--the commercialized treatments (in the form of medicalization) caused by downright greed (!) the closest to a cure i might have truly felt, was hearing that i may never be "cured"

d

 

Re: Cold Heartless Psychiatrists (some not all) almondjoy

Posted by helenag on May 31, 2004, at 23:43:34

In reply to Re: Cold Heartless Psychiatrists (some not all) Questionmark, posted by almondjoy on May 29, 2004, at 23:06:34

An acquaintance of mine who is an advocate for the National Alliance for the Mentally Ill (NAMI) and travels around the country, (he himself suffers greatly and you'd never find a more open person to go to when yourself are in need of a shoulder) said something really neat.

To a scoffer at a recent conference who was questioning him about mental illness, this fellow said: "Sir, this is no such thing as a 'NORMAL PERSON.' You just have not yet been diagnosed nor had an incident."

Here, here!!

No one needs to accept a sentence of feeling a certain way for the rest of his or her life. Mental illnesses can be managed; we can learn to live with our symptoms the best we can; we don't have to throw up our hands and give up hope.

And I have been on the edge of giving up hope, believe me. The hospital bills are still coming in. I have tried many many drug cocktails. My story is not unlike many of yours.

However, I am certain that learning to live within the limitations of mental illness is one way to escape that hell of a lie that my life will always be dark and void of meaning.

 

Re: Cold Heartless Psychiatrists (some not all)

Posted by Sebastian on June 1, 2004, at 18:22:09

In reply to Cold Heartless Psychiatrists (some not all), posted by Questionmark on May 28, 2004, at 17:27:21

I think they are just saying the help will always be there. you won't forget depression, not completly. But I think if you can make the changes in life to make you happy, and get off meds slowly. You can feel happy again.

Ps. Don't beat me up if you think I'm full of it.

 

Redirect to Cold Heartless Psychiatrists board (nm)

Posted by Terry on June 2, 2004, at 14:08:32

In reply to Re: Cold Heartless Psychiatrists (some not all), posted by Sebastian on June 1, 2004, at 18:22:09

 

Re: Cold Heartless Psychiatrists (some not all)

Posted by Questionmark on June 2, 2004, at 21:50:14

In reply to Re: Cold Heartless Psychiatrists (some not all), posted by Sebastian on June 1, 2004, at 18:22:09

almondjoy, helenag, and Sebastian:
you all made some great points about this topic, and interestingly each of your posts made similar points but in different, unique ways. But thank you, i see what you mean. There is a way for psychiatrists to say things such as [the comments we have been discussing] and be good-intentioned, kind, encouraging, helpful, and the like.
i guess there is just such a fine line between saying something like that in an insightful, encouraging manner and in a careless, discouraging manner-- such a fine line but still a big difference. Anyway, that's all.

P.S. (so that this thread stays on the subject of meds), which do you think generally causes more severe dependency and withdrawal syndrome: SSRIs or benzodiazepines?
i've been wondering about this for awhile.

 

Re: Cold Heartless Psychiatrists (SSRI's) Questionmark

Posted by Sebastian on June 4, 2004, at 20:55:59

In reply to Re: Cold Heartless Psychiatrists (some not all), posted by Questionmark on June 2, 2004, at 21:50:14

In my opinion, SSRI's produce no dependancy. Infact I take one for a while and want to just stop it, have no problems doing so, infact I enjoy it more than taking the SSRI. I've been decreasing my Celexa lately, was on 80 mg now 40 mg. Feeling 100% better each time. Wouldn't mind stoping if I could convince my pdoc, I've asked.

I have not taken the benzo's.


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