Psycho-Babble Medication Thread 348098

Shown: posts 1 to 19 of 19. This is the beginning of the thread.

 

decongestants and MAOIs

Posted by cybercafe on May 18, 2004, at 9:02:59

okay so i'm on 40 mg parnate

my doc says pseudoephedrine is okay but antihistamines are not

but when i read the label, apparently pseudoephendrine-containing drugs are the ones that are contra-indicated...

comments??

 

Re: decongestants and MAOIs

Posted by King Vultan on May 18, 2004, at 11:56:23

In reply to decongestants and MAOIs, posted by cybercafe on May 18, 2004, at 9:02:59

> okay so i'm on 40 mg parnate
>
> my doc says pseudoephedrine is okay but antihistamines are not
>
> but when i read the label, apparently pseudoephendrine-containing drugs are the ones that are contra-indicated...
>
> comments??


No, this is absolutely backwards:

Pure antihistamines (Benadryl is a good example) are okay.

Decongestants (pseudoephedrine is a good example) are prohibited.

I take 90 mg/day Nardil and use 50 mg/night generic diphenhydramine (Benadryl) for sleep. I asked my doctor about this first because I thought it was good to be cautious, and he said that the pure Benadryl was fine, and that the versions with pseudoephedrine and other stuff should be avoided.

If your doctor actually said what you indicated and you aren't just misremembering it, he is guilty of a grave error. I would suggest calling in to talk to a nurse or someone who could relay a message to him if you are still apprehensive or unsure about this.

Todd

 

Re: decongestants and MAOIs

Posted by cybercafe on May 18, 2004, at 13:11:55

In reply to Re: decongestants and MAOIs, posted by King Vultan on May 18, 2004, at 11:56:23

> > okay so i'm on 40 mg parnate
> >
> > my doc says pseudoephedrine is okay but antihistamines are not
> >
> > but when i read the label, apparently pseudoephendrine-containing drugs are the ones that are contra-indicated...
> >
> > comments??
>
>
> No, this is absolutely backwards:
>
> Pure antihistamines (Benadryl is a good example) are okay.
>
> Decongestants (pseudoephedrine is a good example) are prohibited.
>
> I take 90 mg/day Nardil and use 50 mg/night generic diphenhydramine (Benadryl) for sleep. I asked my doctor about this first because I thought it was good to be cautious, and he said that the pure Benadryl was fine, and that the versions with pseudoephedrine and other stuff should be avoided.
>
> If your doctor actually said what you indicated and you aren't just misremembering it, he is guilty of a grave error. I would suggest calling in to talk to a nurse or someone who could relay a message to him if you are still apprehensive or unsure about this.
>
> Todd
>
>

thanks for the reply bro, much appreciated

 

Re: decongestants and MAOIs cybercafe

Posted by jerrympls on May 18, 2004, at 20:16:02

In reply to decongestants and MAOIs, posted by cybercafe on May 18, 2004, at 9:02:59

> okay so i'm on 40 mg parnate
>
> my doc says pseudoephedrine is okay but antihistamines are not
>
> but when i read the label, apparently pseudoephendrine-containing drugs are the ones that are contra-indicated...
>
> comments??

Stay away from decongestants and cough suppressants. I accidentally took some Nyquil while on Nardil and was in intensive care for 24 hours because of SEVERE serotonin syndrome - my body overheated, wouldn't stop violently shaking and almost had kidney failure.

Really - be careful.

 

maoi people, please help

Posted by platinumbride on May 19, 2004, at 15:09:01

In reply to Re: decongestants and MAOIs cybercafe, posted by jerrympls on May 18, 2004, at 20:16:02

A few weeeks ago I posted about my pdoc ordering a compound of selegiline in a cream form - as a pre-cursor to the selegiline patch, and as an introduction, I guess, to the maoi world. This was an experiment - I wasn't sure it would work, but figured it to be as good as any other shot in the dark drug.

It seemed to me that some of the drug was being absorbed - the old weird taste thing. And yet I feel like a fool, putting this stupid cream on and, after two weeks, not feeling any better.

So one day I decide to take some sudafed, knowing that it is seriously verbotten with selegiline, but not really believing that the selegiline is going anywhere with me.

The result: Clear sinuses. The same is true of the second and then third time I took sudafed after rubbing the stupid cream in.

After reading this thread, I am feeling pretty sure that I am not getting an effective amount of seligiline, but I would really appreciate opinions. If I were getting any real absorption, I imagine that the sudafed would have been a MAJOR problem. Does anyone agree or disagree? Is it worth giving this stuff its 6-8 weeks or should I consider parnate or some other maoi?

I feel as if I am running out of options with meds and I know that most people on this board know how that makes you feel.....going down down down.
Diane

 

Re: maoi people, please help platinumbride

Posted by Ilene on May 19, 2004, at 21:26:32

In reply to maoi people, please help, posted by platinumbride on May 19, 2004, at 15:09:01

> A few weeeks ago I posted about my pdoc ordering a compound of selegiline in a cream form - as a pre-cursor to the selegiline patch, and as an introduction, I guess, to the maoi world. This was an experiment - I wasn't sure it would work, but figured it to be as good as any other shot in the dark drug.
>
> It seemed to me that some of the drug was being absorbed - the old weird taste thing. And yet I feel like a fool, putting this stupid cream on and, after two weeks, not feeling any better.
>
> So one day I decide to take some sudafed, knowing that it is seriously verbotten with selegiline, but not really believing that the selegiline is going anywhere with me.
>
> The result: Clear sinuses. The same is true of the second and then third time I took sudafed after rubbing the stupid cream in.
>
> After reading this thread, I am feeling pretty sure that I am not getting an effective amount of seligiline, but I would really appreciate opinions. If I were getting any real absorption, I imagine that the sudafed would have been a MAJOR problem. Does anyone agree or disagree? Is it worth giving this stuff its 6-8 weeks or should I consider parnate or some other maoi?
>
> I feel as if I am running out of options with meds and I know that most people on this board know how that makes you feel.....going down down down.
> Diane
>

I don't know whether your experiment proves anything--food and drug interactions w/ MAOIs are supposed to be idiosyncratic. I *have* read that a high enough dose of Selegiline to be effective as an AD, no matter what the route of administration, has the same food and drug proscriptions as the other MAOIs, so why use it in a cream? I'd take something in pill form.

I'm using Marplan. Its side effect profile is between Parnate and Nardil. It didn't do anything until I augmented with Cytomel (thyroid). I'll probably replace the Marplan with something that's compatible w/ a wider variety of ADs, since I think the Cytomel is the key ingredient here.
>
>
>
>
>

 

thanks Ilene (nm)

Posted by platinumbride on May 20, 2004, at 11:21:57

In reply to Re: maoi people, please help platinumbride, posted by Ilene on May 19, 2004, at 21:26:32

 

Re: maoi people, please help

Posted by platinumbride on May 20, 2004, at 11:29:40

In reply to Re: maoi people, please help platinumbride, posted by Ilene on May 19, 2004, at 21:26:32

For those who have had success with maois, how long was it before you started feeling better?

I have done ten days on this selegiline cream compound and feel no aprecaible difference. I thought that the maois worked faster than ssris. I wonder if it is too soon to give up, but I also seriously wonder how much of this stuff is winding up on my clothes rather than in my body.

Thanks,

Diane

 

Re: maoi people, please help

Posted by King Vultan on May 21, 2004, at 7:48:51

In reply to Re: maoi people, please help, posted by platinumbride on May 20, 2004, at 11:29:40

> For those who have had success with maois, how long was it before you started feeling better?
>
> I have done ten days on this selegiline cream compound and feel no aprecaible difference. I thought that the maois worked faster than ssris. I wonder if it is too soon to give up, but I also seriously wonder how much of this stuff is winding up on my clothes rather than in my body.
>
> Thanks,
>
> Diane


I'm rather old fashioned and take the Nardil pills, putting up with the dietary restrictions, which are fairly minor IMO. I'm not sure how it translates to your situation, but I had to get up to 2/3 of the maximum dose before even noticing any side effects, which took about five days or so to appear after going to that dose. After increasing the dose again, it took a similar period of time for therapeutic effects to be noticeable. I'm currently on the maximum recommended dose and am doing okay.

If you're using a patch or some similar method to administer the drug, I can see where it might be a little more iffy. There are drawbacks to pills also, which you have to remember to take, and since my doctor is also fairly conservative, he is having me take my Nardil pills throughout the day. I am happy to do so, but occasionally forget and wind up an hour or two late on some doses.

Todd

 

Re: maoi people, please help

Posted by cybercafe on May 21, 2004, at 22:12:23

In reply to Re: maoi people, please help, posted by platinumbride on May 20, 2004, at 11:29:40

> For those who have had success with maois, how long was it before you started feeling better?
>
> I have done ten days on this selegiline cream compound and feel no aprecaible difference. I thought that the maois worked faster than ssris. I wonder if it is too soon to give up, but I also seriously wonder how much of this stuff is winding up on my clothes rather than in my body.
>
> Thanks,
>
> Diane

i think parnate worked immediately (stimulant properties) but then gave out after 1 month... then took 2 more months before the AD effect really kicked in ... and even then i had to push myself to do things... but when i finally did push myself, it worked like nothing else ever has .... so i'd say in my experience MAOIs take longer to work ....

 

Re: maoi people, please help

Posted by gardenergirl on May 21, 2004, at 23:46:16

In reply to Re: maoi people, please help, posted by King Vultan on May 21, 2004, at 7:48:51

I take my Nardil throughout the day, too. I have to have an alarm go off to remind me, especially once I went from 45 mg to 60 mg (3 to 4 pills per day).

I noticed a stimulant effect right away. The AD effect took a bit longer, at least two weeks, but it has been several months, so I can't really remember.

Did your doc. prescribe the selegine cream for depression? It seems like an inconsistent way to administer it. Hopefully the patch will be out soon.

I would love it if they would come out with an extended release Nardil or a patch or something. Taking multiple doses throughout the day is a pain. I sometimes am off by an hour or two as well.

Good luck,
gg

 

thanks again, and a few more? weight, anxiety.....

Posted by platinumbride on May 22, 2004, at 10:11:55

In reply to Re: maoi people, please help, posted by gardenergirl on May 21, 2004, at 23:46:16

From my following of posts here, parnate seems to be my next drug of choice because nardil seems to have caused weight gain for many but parnate did not....yet I remember seeing a few say that the opposite was true. I know everyone is different, but I really can't afford to gain anymore weight.

I'm a little fearful of stimulant responses because I have anxiety issues too. Is it a good stimulant feeling or a paralyzing anxiety stim feeling?

Does doseage have to do with body weight or do you have to just have your blood levels checked?
I never had them checked before, with ssris or remeron. Is is different with the maois?

Thank you all so very much...

Diane

 

Re: thanks again, and a few more? weight, anxiety..... platinumbride

Posted by Ilene on May 22, 2004, at 10:46:26

In reply to thanks again, and a few more? weight, anxiety....., posted by platinumbride on May 22, 2004, at 10:11:55

> From my following of posts here, parnate seems to be my next drug of choice because nardil seems to have caused weight gain for many but parnate did not....yet I remember seeing a few say that the opposite was true. I know everyone is different, but I really can't afford to gain anymore weight.
>
> I'm a little fearful of stimulant responses because I have anxiety issues too. Is it a good stimulant feeling or a paralyzing anxiety stim feeling?
>

That's why I chose Marplan. The side effects are between Nardil and Parnate. I didn't want to gain weight, but I wasn't sure I could handle the stimulant effects. I also have GAD, so anxiety is a problem for me.

> Does doseage have to do with body weight or do you have to just have your blood levels checked?
> I never had them checked before, with ssris or remeron. Is is different with the maois?
>

No, blood levels are irrelevant.

Ilene

 

Question(s) about your Parnate experience cybercafe

Posted by Questionmark on May 24, 2004, at 2:21:04

In reply to Re: maoi people, please help, posted by cybercafe on May 21, 2004, at 22:12:23

> i think parnate worked immediately (stimulant properties) but then gave out after 1 month... then took 2 more months before the AD effect really kicked in ... and even then i had to push myself to do things... but when i finally did push myself, it worked like nothing else ever has .... so i'd say in my experience MAOIs take longer to work ....

i was on Parnate for about 2 or 3 months last year, and the appetite suppression (which i did not want), excessive anxiety, and hORRibly over-emotional state of mind (which made me even MORE depressed) never went away. However, i think it was slightly helpful for maybe the first week-- some stimulant-like mood-lifting properties without the comedown (although the aforementioned negative effects were still present). But/so i was wondering if you think that i might have had a positive experience with it eventually if i had waited like an extra month or so before quitting it. Also, what do you mean exactly when you say that it "gave out after 1 month"? How did it give out? What were the feelings and effects like? And, if you don't mind, what were the feelings and effects like while it was benefitting you (or what *are* they like if you're still on it)? Thanks alot.

 

Re: maoi people, please help

Posted by Maxime on May 24, 2004, at 12:13:27

In reply to Re: maoi people, please help, posted by King Vultan on May 21, 2004, at 7:48:51

I take Parnate. 80 Mg a day. Within one week I felt the difference and I was on 30 mg. Just a minor difference. The following week others noticed a difference. I think because Parnate can make you peppy at first. I finally landed at 80 mg because that is what worked best for me. I am still depressed but not as bad as before. If I take any higher than 80 mg I suffer side effects. So I am staying at 80 mg.

Maxime


 

Re: Question(s) about your Parnate experience

Posted by cybercafe on May 25, 2004, at 2:04:22

In reply to Question(s) about your Parnate experience cybercafe, posted by Questionmark on May 24, 2004, at 2:21:04

> > i think parnate worked immediately (stimulant properties) but then gave out after 1 month... then took 2 more months before the AD effect really kicked in ... and even then i had to push myself to do things... but when i finally did push myself, it worked like nothing else ever has .... so i'd say in my experience MAOIs take longer to work ....
>
> i was on Parnate for about 2 or 3 months last year, and the appetite suppression (which i did not want), excessive anxiety, and hORRibly over-

yeah my anxiety is still bad, but was worse on SSRIs or no meds... i think parnate did wonders for my anxiety, but it's still not perfect... strangely enough, cute girls scare me little but being in a room with friends kind of intimidates me ...

>emotional state of mind (which made me even >MORE depressed) never went away. However, i >think it

yeah... well i feel pretty good.. i might take a small amount of klonazepam (okay maybe a big amount) if i feel over emotional.. but i still know i need major therapy if i want to do something major stressful like go into med school

>was slightly helpful for maybe the first week-- some stimulant-like mood-lifting properties without the comedown (although the aforementioned negative effects were still present). But/so i was wondering if you think that i might have had a positive experience with it eventually if i had waited like an extra month or so before quitting it. Also, what do

yeah if you are like me, which you may or may not be... when i stated this hypothesis to my doctor, he agreed like very matter-of-factly ...

i mean i have heard of other people who hadn't had the full anti-anxiety effects of parnate or nardil until after the 3rd month, so that's what made me stick with it... also i think my doc suggested i wait that long.... about 12 weeks first time around, 16 weeks second... BUT it never really "kicked in"... i sort of was taking it, feeling 60% better, then decided to push myself and socialize and felt 90% better... i have never experienced this benefit from pushing myself to socialize or do other fun things when i took SSRIs/SNRIs ...

>you mean exactly when you say that it "gave out >after 1 month"? How did it give out? What were the feelings and effects like? And, if you


dude i seriously don't remember... just depression coming back is all i can remember in general.. not feeling that sort of buzz or high or whatever it was when i first took it... i think i felt a bit manic when i first took it or i somehow knew it was working too fast so i wasn't too surprised when the effects waned a bit... and then waned a lot! .. but i hung in there, and eventually the AD effects finally kicked in, with time, and putting in the effort to get my life in order.......... i don't think you can ever get over depression without having a good environment ... at least not 100%, not me personally....

>don't mind, what were the feelings and effects like while it was benefitting you (or what *are* they like if you're still on it)? Thanks alot.

gee... what's it like to be depressed? i don't really remember...
i guess i just enjoy things... i get pleasure from things... i never used to feel the same pleasure when i was depressed... it also makes me want to do things (though abilify is probably even better for this)... have ambition... think about the future and all the things i can do...


okay biggest difference i can mention between depression and taking ADs in general (SSRIs) is...

depressed i wake up, no thoughts in head of anything i'd like/need to do, wonder why i'm awake, go back to sleep

on ADs, i wake up, have thoughts of all these things that are important or fun or whatever, just trigger emotions, and i jump out of bed and get on with them... like serotonin is like a pressure in my head to do things (not even the extreme mania form, just the normal normal dude form) ... without it, it's like there's no force pushing you to do anything, so you just sit there and do nothing and then feel bored and depressed... and if you FORCE yourself to do things, you depression may go away, but you may also not have the pressure feeling thingy to enable you to keep that up ...

it's actually really hard to say right now, i think i would be somewhat hypomanic or cycling but the tiny dose of abilify helps me from going too high

all the information is out there if you want to do a
www.google.ca
site:dr-bob.org cybercafe parnate

maybe it's also like parnate blocks out feelings... feelings of guilt, sadness etc... and replaces them with feelings of.... interest? purpose? confidence?

sorry i can't be more helpful.... but that's why i write everything online.... so if ever i want to go back to see how i used to feel... i can just search dr. bob's site! :)

god i remember before parnate kicked in i was reading posts i had written telling people every problem was solvable, how life was wonderful, how i could fix them up no problem, how everything was so easy .... and i would do all this work, like dig out documents for people, etc etc and i thought "wow... i was so positive and motivated when that drug was working last time... i wish my doc had never taken me off it.... everyday is painful for me now... i am lucky just to make it through the waiting period" ... so that was a big revelation for me... without parnate i seem lethargic and i don't want to do anythingl... with parnate i am enthusiastic and want to get things done... !!! whatever it takes!! \

hope that helps... feel free to ask for clarification/more questions... on parnate i feel like i can tackle anything.. and like i'm really making a difference... :)

 

Re: Question(s) about your Parnate experience cybercafe

Posted by Questionmark on May 25, 2004, at 7:50:25

In reply to Re: Question(s) about your Parnate experience, posted by cybercafe on May 25, 2004, at 2:04:22

> > > i think parnate worked immediately (stimulant properties) but then gave out after 1 month... then took 2 more months before the AD effect really kicked in ... and even then i had to push myself to do things... but when i finally did push myself, it worked like nothing else ever has .... so i'd say in my experience MAOIs take longer to work ....
> >
> > i was on Parnate for about 2 or 3 months last year, and the appetite suppression (which i did not want), excessive anxiety, and hORRibly over-
>
> yeah my anxiety is still bad, but was worse on SSRIs or no meds... i think parnate did wonders for my anxiety, but it's still not perfect... strangely enough, cute girls scare me little but being in a room with friends kind of intimidates me ...
>
> >emotional state of mind (which made me even >MORE depressed) never went away. However, i >think it
>
> yeah... well i feel pretty good.. i might take a small amount of klonazepam (okay maybe a big amount) if i feel over emotional.. but i still know i need major therapy if i want to do something major stressful like go into med school
>
> >was slightly helpful for maybe the first week-- some stimulant-like mood-lifting properties without the comedown (although the aforementioned negative effects were still present). But/so i was wondering if you think that i might have had a positive experience with it eventually if i had waited like an extra month or so before quitting it. Also, what do
>
> yeah if you are like me, which you may or may not be... when i stated this hypothesis to my doctor, he agreed like very matter-of-factly ...
>
> i mean i have heard of other people who hadn't had the full anti-anxiety effects of parnate or nardil until after the 3rd month, so that's what made me stick with it... also i think my doc suggested i wait that long.... about 12 weeks first time around, 16 weeks second... BUT it never really "kicked in"... i sort of was taking it, feeling 60% better, then decided to push myself and socialize and felt 90% better... i have never experienced this benefit from pushing myself to socialize or do other fun things when i took SSRIs/SNRIs ...
>
> >you mean exactly when you say that it "gave out >after 1 month"? How did it give out? What were the feelings and effects like? And, if you
>
>
> dude i seriously don't remember... just depression coming back is all i can remember in general.. not feeling that sort of buzz or high or whatever it was when i first took it... i think i felt a bit manic when i first took it or i somehow knew it was working too fast so i wasn't too surprised when the effects waned a bit... and then waned a lot! .. but i hung in there, and eventually the AD effects finally kicked in, with time, and putting in the effort to get my life in order.......... i don't think you can ever get over depression without having a good environment ... at least not 100%, not me personally....
>
> >don't mind, what were the feelings and effects like while it was benefitting you (or what *are* they like if you're still on it)? Thanks alot.
>
> gee... what's it like to be depressed? i don't really remember...
> i guess i just enjoy things... i get pleasure from things... i never used to feel the same pleasure when i was depressed... it also makes me want to do things (though abilify is probably even better for this)... have ambition... think about the future and all the things i can do...
>
>
> okay biggest difference i can mention between depression and taking ADs in general (SSRIs) is...
>
> depressed i wake up, no thoughts in head of anything i'd like/need to do, wonder why i'm awake, go back to sleep
>
> on ADs, i wake up, have thoughts of all these things that are important or fun or whatever, just trigger emotions, and i jump out of bed and get on with them... like serotonin is like a pressure in my head to do things (not even the extreme mania form, just the normal normal dude form) ... without it, it's like there's no force pushing you to do anything, so you just sit there and do nothing and then feel bored and depressed... and if you FORCE yourself to do things, you depression may go away, but you may also not have the pressure feeling thingy to enable you to keep that up ...
>
> it's actually really hard to say right now, i think i would be somewhat hypomanic or cycling but the tiny dose of abilify helps me from going too high
>
> all the information is out there if you want to do a
> www.google.ca
> site:dr-bob.org cybercafe parnate
>
> maybe it's also like parnate blocks out feelings... feelings of guilt, sadness etc... and replaces them with feelings of.... interest? purpose? confidence?
>
> sorry i can't be more helpful.... but that's why i write everything online.... so if ever i want to go back to see how i used to feel... i can just search dr. bob's site! :)
>
> god i remember before parnate kicked in i was reading posts i had written telling people every problem was solvable, how life was wonderful, how i could fix them up no problem, how everything was so easy .... and i would do all this work, like dig out documents for people, etc etc and i thought "wow... i was so positive and motivated when that drug was working last time... i wish my doc had never taken me off it.... everyday is painful for me now... i am lucky just to make it through the waiting period" ... so that was a big revelation for me... without parnate i seem lethargic and i don't want to do anythingl... with parnate i am enthusiastic and want to get things done... !!! whatever it takes!! \
>
> hope that helps... feel free to ask for clarification/more questions... on parnate i feel like i can tackle anything.. and like i'm really making a difference... :)


That's really interesting stuff. Thanks for the in depth response.
i think Parnate probably affects me different than you. For instance, when i was on it my feelings of guilt, sadness, regret, etc. were compounded tremendously. Now maybe i wasn't on it long enough, and i do especially wonder now if it may have had more anxiolytic effects if i had stayed on it longer. But i don't think so, unfortunately. Like i never experienced a 60% improvement at all. i'm pretty sure i felt worse overall. i did love how much more intelligent and articulate it made me though.
Also, i have Obsessive Compulsive *Personality*, which is a real pain in the ***. You might not know much about it (overfocusing, extreme perfectionism and black & white thinking/behavior, taking horrendously absurd lengths of time to do ANything, indecisiveness, procrastination, etc.), but the Parnate made that (or the associated problems) much worse-- and they're far too bad already. i guess that's a big difference that i would have with alot of people and not just you, in respect to Parnate. But-- if by some highly unlikely chance that you would be able to know this or have an informed opinion on this, and that there is actually any chance that the answer to this question would be positive-- do you think that if i took Parnate longer (say 12 weeks or so) it might have beneficial effects, or at least negligible effects, on my OCP problems?
Okay that's just a stupid question because 1) i seriously doubt you would have any idea and 2) Parnate has such strong catecholaminergic effects that the aggravation of my OCP symptoms makes perfect sense and it would be highly unlikely that they would diminish that much. But i thought i'd be naive and ask anyway.
Also, how often do you take Klonopin while you're on Parnate? i had thought that the combination of the two would be a good one.
Thanks again.

 

Parnate thoughts

Posted by harryp on May 25, 2004, at 16:47:57

In reply to Re: Question(s) about your Parnate experience cybercafe, posted by Questionmark on May 25, 2004, at 7:50:25

I'm really glad to hear so much about Parnate's effect on different people.

This drug is really fascinating, and appears to have pretty unique effects.

I found it really interesting to hear about Parnate causing excessive emotion.

The reason I can't tolerate other AD's and especially antipsychotics is because they "made me stupid" and messed up my emotions. Since I have no life, my reading and creative work is all that keeps me going most of the time. Take that away, and no "happy pill" is going to make me feel that life is worth living.

I found Parnate truly remarkable because it was the first psychotropic I had ever taken that didn't make me feel dull and not-all-there. When I raised the dose to 40mg the effect was remarkable. I felt fatigued (a SE that went away) but the turmoil, self-hatred, anxiety, etc. that was churning around in my head suddenly calmed, and I realized I couldn't remember the last time I could think so clearly. I chilled out on the sofa and read Kant's "Groundwork for the Metaphysics of Morals," and not only had no difficulty understanding it, but really ENJOYED IT! It was like a miracle.

I think my emotions are more extreme on Parnate--I've had horrible episodes of suicidal depression plenty of times. That's a price I'm more than willing to pay for having my brain back, being able to get out of bed every morning, and being able to really relate to the close friends I have and fully experience those rare moments of real happiness.

 

Re: Question(s) about your Parnate experience

Posted by cybercafe on May 26, 2004, at 1:58:04

In reply to Re: Question(s) about your Parnate experience cybercafe, posted by Questionmark on May 25, 2004, at 7:50:25

> That's really interesting stuff. Thanks for the in depth response.
> i think Parnate probably affects me different than you. For instance, when i was on it my feelings of guilt, sadness, regret, etc. were compounded tremendously. Now maybe i wasn't on

ummm.... yeah i actually felt that way for a while ... while on parnate... but it eventually went away, as i started socializing more and time went by etc


it long enough, and i do especially wonder now if it may have had more anxiolytic effects if i had stayed on it longer. But i don't think so, unfortunately. Like i never experienced a 60% improvement at all. i'm pretty sure i felt worse overall. i did love how much more intelligent and articulate it made me though.
> Also, i have Obsessive Compulsive *Personality*, which is a real pain in the ***. You might not know much about it (overfocusing, extreme perfectionism and black & white thinking/behavior, taking horrendously absurd lengths of time to do ANything, indecisiveness, procrastination, etc.), but the Parnate made

okay i have this too, but i always thought it was ADD

that (or the associated problems) much worse-- and they're far too bad already. i guess that's a big difference that i would have with alot of people and not just you, in respect to Parnate. But-- if by some highly unlikely chance that you would be able to know this or have an informed opinion on this, and that there is actually any chance that the answer to this question would be positive-- do you think that if i took Parnate longer (say 12 weeks or so) it might have beneficial effects, or at least negligible effects, on my OCP problems?

yes i think that parnate had a good effect on those symptoms, but i also think abilify had an awesome effect as well


> Okay that's just a stupid question because 1) i seriously doubt you would have any idea and 2) Parnate has such strong catecholaminergic effects that the aggravation of my OCP symptoms makes perfect sense and it would be highly unlikely that they would diminish that much. But i thought i'd be naive and ask anyway.
> Also, how often do you take Klonopin while you're on Parnate? i had thought that the combination of the two would be a good one.

well my anxiety is pretty bad and i put myself in the toughest social situations imaginable where i need to be fearless so i will go up to 2mg of clonazepam 2 or 3 times a day.... but parnate has definately cut down on my anxiety a lot

> Thanks again.

no problem, glad to help


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