Psycho-Babble Medication Thread 336205

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Re: Must I stop my beloved Nardil????? » Flipsactown

Posted by ace on April 15, 2004, at 0:45:36

In reply to Re: Must I stop my beloved Nardil?????, posted by Flipsactown on April 14, 2004, at 17:51:05

> Ace,
>
> Please tell me that Nardil is still working in relieving your depression.

Oh it definately is! And now that I have added some L-Tryptophan I am feeling some of the old euphoric quality i got with Nardil!

I just started Nardil 5 days ago and was counting on it to relieve my unipolar depression. I decided on switching to Nardil after I read your Nardil Rules Posts. How long did it take you to feel your depression lift after taking Nardil? Does Nardil still rule?

YESIT RULES!!! Big time! But it took 6 weeks. 4 of those weeks at 60mg. For 3 months, before I first stopped Nardil, I was in bliss. Now I am just happy. But thats good!

Nardil rules!

Ace

>
> FST
>
> > I'm running out of options for OCD guys!
> >
> > Clomipramine + Luvox + Buspar would kill the OCD!
> >
> >
> > But I need some more things to try with Nardil...
> >
> > I have tried the following with no effect on OCD
> >
> > 1. Nardil + Lithium
> > 2. Nardil + Pindolol (increases depression after a few doses)
> > 3. Nardil + Reboxetine (increased depression after 2 doses)
> > 4. Nardil + Seroquel (increased derealization/anxiety after one dose)
> > 5. Nardil + Amisulpride
> >
> > ##6. Nardil + Zyprexa 2.5mg (50% relief) (but I tried 5mg and it seemed no better than 2.5)
> >
> >
> > Help me dudes! ANTI OCD AGENTS NOW!!!!!
> >
> > Ace...
>
>

 

Re: Must I stop my beloved Nardil????? » Sad Panda

Posted by ace on April 15, 2004, at 0:54:30

In reply to Re: Must I stop my beloved Nardil????? ?ace, posted by Sad Panda on April 14, 2004, at 13:45:49


>
> What happens when you go to a higher dose of just Nardil?
>
> Cheers,
> Panda.
>
>

No effect on OCD. When Im on Zyprexa 90mg makes me more depressed usually! But as montherapy 90mg doesn't make me depressed. For 3 months last year 90mg was causing euphoria! Thats when I was on Nardil alone or Nardil + Lithium.

Ace.

>

 

Re: Must I stop my beloved Nardil?????

Posted by SLS on April 15, 2004, at 10:08:07

In reply to Must I stop my beloved Nardil?????, posted by ace on April 14, 2004, at 2:11:37

Risperdal is a strange beast. For some people it works wonders for refractory OCD. For others, however, it actually induces OCD. I know it's not the prettiest drug in the world, but if you want to tackle the OCD bad enough, it might be worth a quick trial.

By the way, what exactly are your symptoms of OCD?


- Scott

 

Re: Must I stop my beloved Nardil????? » Flipsactown » ace

Posted by Flipsactown on April 15, 2004, at 18:58:13

In reply to Re: Must I stop my beloved Nardil????? » Flipsactown, posted by ace on April 15, 2004, at 0:45:36

I had asked my pdoc through his nurse, (I belong to Kaiser Permanente Health plan), if I could get something to counter insomnia from Nardil like Trazodone or Ambien and she called me back, today, after she had talked to my pdoc and said that my pdoc could not and would not rx either due to possible fatal drug interactions. I knew he probably would not rx either because he is such a conservative, by the book, pdoc. I have been only getting 2 to 4 hours sleep since I started taking Nardil 6 days ago and I am only taking 15mg daily. At this rate, my depression will worsen due to sleep deprivation so what good is taken Nardil if I can't get a good night sleep. Any suggestions?

FST


> > Ace,
> >
> > Please tell me that Nardil is still working in relieving your depression.
>
> Oh it definately is! And now that I have added some L-Tryptophan I am feeling some of the old euphoric quality i got with Nardil!
>
> I just started Nardil 5 days ago and was counting on it to relieve my unipolar depression. I decided on switching to Nardil after I read your Nardil Rules Posts. How long did it take you to feel your depression lift after taking Nardil? Does Nardil still rule?
>
> YESIT RULES!!! Big time! But it took 6 weeks. 4 of those weeks at 60mg. For 3 months, before I first stopped Nardil, I was in bliss. Now I am just happy. But thats good!
>
> Nardil rules!
>
> Ace
>
>
>
> >
> > FST
> >
> > > I'm running out of options for OCD guys!
> > >
> > > Clomipramine + Luvox + Buspar would kill the OCD!
> > >
> > >
> > > But I need some more things to try with Nardil...
> > >
> > > I have tried the following with no effect on OCD
> > >
> > > 1. Nardil + Lithium
> > > 2. Nardil + Pindolol (increases depression after a few doses)
> > > 3. Nardil + Reboxetine (increased depression after 2 doses)
> > > 4. Nardil + Seroquel (increased derealization/anxiety after one dose)
> > > 5. Nardil + Amisulpride
> > >
> > > ##6. Nardil + Zyprexa 2.5mg (50% relief) (but I tried 5mg and it seemed no better than 2.5)
> > >
> > >
> > > Help me dudes! ANTI OCD AGENTS NOW!!!!!
> > >
> > > Ace...
> >
> >
>
>

 

Re: Must I stop my beloved Nardil?????

Posted by djmmm on April 15, 2004, at 21:12:05

In reply to Re: Must I stop my beloved Nardil????? » Flipsactown » ace, posted by Flipsactown on April 15, 2004, at 18:58:13

try melatonin...I find it works better than benzos for sleep...plus I have yet to see any rebound insomnia or tolerance

 

Re: Must I stop my beloved Nardil????? » SLS

Posted by ace on April 16, 2004, at 1:30:03

In reply to Re: Must I stop my beloved Nardil?????, posted by SLS on April 15, 2004, at 10:08:07

> Risperdal is a strange beast. For some people it works wonders for refractory OCD. For others, however, it actually induces OCD. I know it's not the prettiest drug in the world, but if you want to tackle the OCD bad enough, it might be worth a quick trial.
]
Ill keep it in mind.


>
> By the way, what exactly are your symptoms of OCD?
>
>
> - Scott

Scott, my symptoms are atypical and refractory at the moment.

Caveats...

1. Reality Testing and cognition remain firmly intact...ie it is not a psychosis.

2. All symptoms are ego-dystonic and painful.


Symptoms

1. an idea comes into my head that it will be 'bad' if i do this or that. then this thought comes and says 'yes' to the bad thought. But i have to 'protect' myself from the 'bad' thought and say 'no' over it before the 'yes' gets in.

Get it?! Wierd huh?

2. I can ruminate on past 'bad' thoughts which have 'come through' and been said 'yes' too. Like if i write a essay a thought will come and try and defile this essay. If the bad thought gets said 'yes' too, i then have very strong negative, stifling, and painful sensations to do with this essay. it hurts and stifles any feeling of growth accomplashment, etc.

I know this seem to make no sense but who said OCD makes sense!

3. More 'normal' OCD- hoarding, checking, etc

4. I have OCPD too.


Tell me what you think Scott. I respect you bro.

Do you think Zyprexa 10mg is worth a shot?

Ace.

 

Re: Must I stop my beloved Nardil????? » ace

Posted by SLS on April 16, 2004, at 11:36:56

In reply to Re: Must I stop my beloved Nardil????? » SLS, posted by ace on April 16, 2004, at 1:30:03

Hi Ace.

> > By the way, what exactly are your symptoms of OCD?

> Scott, my symptoms are atypical and refractory at the moment.

I wish I were better informed about OCD. However, in light of the atypicality of your symptoms and your many failures to treat them, I guess the logical question to ask is how confident are you that it is indeed OCD that you are treating?

Do you perform any rituals repeatedly?

> 1. an idea comes into my head that it will be 'bad' if i do this or that. then this thought comes and says 'yes' to the bad thought. But i have to 'protect' myself from the 'bad' thought and say 'no' over it before the 'yes' gets in.

I can see how this would be ritualistic. Is there anxiety? More specifically, do you experience an anxiety that can only be relieved by saying "no" repeatedly a certain number of times? How do you compare what you experience from non-OCD intrusive thoughts.

> 2. All symptoms are ego-dystonic and painful.

I can see that you are thoroughly read on this topic.

Just curious - do you meet the criteria of the DSM diagnosis of OCD?

> 2. I can ruminate on past 'bad' thoughts which have 'come through' and been said 'yes' too. Like if i write a essay a thought will come and try and defile this essay. If the bad thought gets said 'yes' too, i then have very strong negative, stifling, and painful sensations to do with this essay. it hurts and stifles any feeling of growth accomplashment, etc.

That must be tormenting.

> 3. More 'normal' OCD- hoarding, checking, etc

I see.

> 4. I have OCPD too.

What's that? I guess I'll go Googling. Be right back...

Hmmm. I see. I can see where the hoarding fits in. I've never heard you speak of perfectionism or the need to be meticulously organized, though. However, I think one could argue that an OPCD need to have things be perfect could drive you to find the perfect drug combination for the attainment of the perfect conscious experience. I should stop here before I start analyzing you. lol ;-)

> Tell me what you think Scott. I respect you bro.

To be honest with you, I don't know you well enough to make any judgment regarding your condition or its treatment. The differential diagnosis between OCD and OPCD can be difficult. OPCD doesn't seem to be as well understood as OCD, and its treatment is still being debated. I guess someone once tried to shove CBT down you throat. However, I can imagine how some type of psychotherapy might be advantageous for some people to help them break looping cognitive cycling. Perhaps looking at the specific content of the patterned thoughts and behaviors would provide a tool to recognize and diffuse the cycles. I find myself rambling as I attempt to brainstorm your situation. I apologize. I wonder if the reason why high-dose SSRI therapy is sometimes effective for OCPD is that it simply produces apathy and passivity such that the driving force is neutralized enough to reduce the energy available to facilitate the perfectionism and ritualism. I would hope that it be more targeted towards the initiation of the obsessive content rather than to simply facilitate its dilution downstream. I get the impression that discriminating the differences between OCD and OPCD, that is to say, establishing a differential diagnosis, might be important at some point. I think you should look closely to see whether or not you can exclude OCD, as it doesn't seem necessary that it and OPCD be comorbid.

> Do you think Zyprexa 10mg is worth a shot?

Of course. You've tried so many things already, you can't afford to leave any stone unturned. I get the feeling that 5-10mg is the sweet spot for the application or Zyprexa in non-psychotic and non-delusional conditions.

There has got to be something out there for you. Keep trying. I offer the possibility that you have OCPD without OCD, in which case using serotonin reuptake inhibitors might be barking up the wrong tree. This is something short of a completely wild guess, though.

You did ask. :-)

I simply don't know enough.

You'll get there. Just keep an open mind. I am very glad that you have found Nardil. You have a wonderfully creative mind, and I think your persistence will pay off.

:-)

Peace be with you...


Sincerely,
Scott

 

Re: Must I stop my beloved Nardil?????

Posted by SLS on April 16, 2004, at 11:59:18

In reply to Re: Must I stop my beloved Nardil????? » ace, posted by SLS on April 16, 2004, at 11:36:56

Please forgive me for my typos.

OPCD = OCPD

:-)

 

Re: ATTN Scotty » SLS

Posted by ace on April 18, 2004, at 23:32:31

In reply to Re: Must I stop my beloved Nardil????? » ace, posted by SLS on April 16, 2004, at 11:36:56

> Hi Ace.
>
> > > By the way, what exactly are your symptoms of OCD?
>
> > Scott, my symptoms are atypical and refractory at the moment.
>
> I wish I were better informed about OCD. However, in light of the atypicality of your symptoms and your many failures to treat them, I guess the logical question to ask is how confident are you that it is indeed OCD that you are treating?

Without a doubt it is OCD. My sister has it and my Uncle has OCPD. It is atypical however. I remember one obsession I had- I used to obsess that I didn't have OCD! This was also painful because all the 'coping' stragedies I learnt rested on a firm diagnosis of OCD, so these coping stragedies were not plausible if i didn't have OCD. I just went around in loops of obsessive thoughts and the compulsion was to 'check' if I really had OCD. This was very painful.

>
> Do you perform any rituals repeatedly?

Yes, but mostly cognitive. The 'no' I say over the 'bad' thought can be seen as the ritual, whereas the 'bad' thought is the obsession. The 'no' thought serves to reduce anxiety- consistent with OCD rituals.


> > 1. an idea comes into my head that it will be 'bad' if i do this or that. then this thought comes and says 'yes' to the bad thought. But i have to 'protect' myself from the 'bad' thought and say 'no' over it before the 'yes' gets in.
>
> I can see how this would be ritualistic. Is there anxiety?

Absolutely. A lot of anxiety attached. And also pain. Mental pain.

More specifically, do you experience an anxiety that can only be relieved by saying "no" repeatedly a certain number of times?

Yes but this is more fluid. Sometimes I must say 'no' 3 times, sometimes 4 times...

How do you compare what you experience from non-OCD intrusive thoughts.

Please restate...
> > 2. All symptoms are ego-dystonic and painful.
>
> I can see that you are thoroughly read on this topic.

Oh yeah. I OBSESSIVELY read about it for years until I realised my 'research' was just a manifestation of OCD.


> Just curious - do you meet the criteria of the DSM diagnosis of OCD?

Absolutely without a doubt. I obsessively went over that too!

>
> > 2. I can ruminate on past 'bad' thoughts which have 'come through' and been said 'yes' too. Like if i write a essay a thought will come and try and defile this essay. If the bad thought gets said 'yes' too, i then have very strong negative, stifling, and painful sensations to do with this essay. it hurts and stifles any feeling of growth accomplashment, etc.
>
> That must be tormenting.
>
It is, but I must emphasis that both Nardil and Zyprexa have made it far less tormenting. Without meds, I dont know what would happen to me.

> > 3. More 'normal' OCD- hoarding, checking, etc
>
> I see.
>
> > 4. I have OCPD too.
>
> What's that? I guess I'll go Googling. Be right back...
>
> Hmmm. I see. I can see where the hoarding fits in. I've never heard you speak of perfectionism or the need to be meticulously organized, though.

I am obsessively rigid about when I have cigarretes. After each hour of study I have one. At 11pm is my last smoke. I am obsessive about the hours I study and get annoyed if people disrup this. Also my room must be very well organized.

However, I think one could argue that an OPCD need to have things be perfect could drive you to find the perfect drug combination for the attainment of the perfect conscious experience.

Very intelligent insight Scott. I am seeking perfection. But I have read of 100% remission from OCD- this is my aim.


I should stop here before I start analyzing you. lol ;-)

Thats OK!!!


> > Tell me what you think Scott. I respect you bro.
>
> To be honest with you, I don't know you well enough to make any judgment regarding your condition or its treatment. The differential diagnosis between OCD and OPCD can be difficult. OPCD doesn't seem to be as well understood as OCD, and its treatment is still being debated. I guess someone once tried to shove CBT down you throat. However, I can imagine how some type of psychotherapy might be advantageous for some people to help them break looping cognitive cycling. Perhaps looking at the specific content of the patterned thoughts and behaviors would provide a tool to recognize and diffuse the cycles. I find myself rambling as I attempt to brainstorm your situation. I apologize.

No nedd to mate! I appreciate your help!

I wonder if the reason why high-dose SSRI therapy is sometimes effective for OCPD is that it simply produces apathy and passivity such that the driving force is neutralized enough to reduce the energy available to facilitate the perfectionism and ritualism.

Good insight again...i tend to agree.


I would hope that it be more targeted towards the initiation of the obsessive content rather than to simply facilitate its dilution downstream. I get the impression that discriminating the differences between OCD and OPCD, that is to say, establishing a differential diagnosis, might be important at some point. I think you should look closely to see whether or not you can exclude OCD, as it doesn't seem necessary that it and OPCD be comorbid.
>
> > Do you think Zyprexa 10mg is worth a shot?
>
> Of course. You've tried so many things already, you can't afford to leave any stone unturned. I get the feeling that 5-10mg is the sweet spot for the application or Zyprexa in non-psychotic and non-delusional conditions.
>
> There has got to be something out there for you. Keep trying. I offer the possibility that you have OCPD without OCD,

After much reflection I believe I have both...

Almost all the psychiatrists I have seen have diagnosed it as OCD, with a possiblity of a psychotic illness (prodromal psychosis)


in which case using serotonin reuptake inhibitors might be barking up the wrong tree. This is something short of a completely wild guess, though.
>
> You did ask. :-)
>
> I simply don't know enough.
>
> You'll get there. Just keep an open mind. I am very glad that you have found Nardil. You have a wonderfully creative mind,

Thanks mate! I am a musician in a band and write a lot. I bet you are creative too. Us 'crazy' folk usually are!!!


and I think your persistence will pay off.
>
> :-)
>
> Peace be with you...
>
>
> Sincerely,
> Scott
>
>
> Thanks so much Scott. I really appreciate your reply and insights. How are you doing yourself mate? Look foward to chatting again soon,

your friend,
Andrew (Ace)
>
>
>

 

Re: ATTN Scotty

Posted by SLS on April 19, 2004, at 6:28:51

In reply to Re: ATTN Scotty » SLS, posted by ace on April 18, 2004, at 23:32:31

Hi Andrew.


> Thanks so much Scott. I really appreciate your reply and insights.

Just don't forget about Risperdal. I have a good feeling about this drug for you. No guarantees, of course.

> How are you doing yourself mate?

I've been worse.

:-)

You'll get there. 100%


- Scott

 

Re: ATTN Scotty

Posted by SLS on April 19, 2004, at 6:45:26

In reply to Re: ATTN Scotty, posted by SLS on April 19, 2004, at 6:28:51

> Hi Andrew.
>
>
> > Thanks so much Scott. I really appreciate your reply and insights.
>
> Just don't forget about Risperdal. I have a good feeling about this drug for you. No guarantees, of course.
>
> > How are you doing yourself mate?
>
> I've been worse.
>
> :-)
>
> You'll get there. 100%
>
>
> - Scott


Just a thought.

Since there is no guarantee that Risperdal will do the trick, and you do recieve benefit from Zyprexa, it might be a reasonable strategy to try the other atypical neuroleptics as well. I would keep the Zyprexa at 5-10mg and test each drug as an add-on in the sequence you feel makes sense.

- Scott

 

Re: ATTN Scotty

Posted by SLS on April 19, 2004, at 10:10:36

In reply to Re: ATTN Scotty, posted by SLS on April 19, 2004, at 6:45:26

One more thought, Ace.

Here I go babbling:

I have had intrusive thoughts from time to time, especially when my depression is more severe. I've learned to allow the thoughts to occur without resistance. After the initial thought completes itself, I have learned to simply ignore it, realizing that it is OK to have these aberrant thoughts. Let it go. Don't pay any attention to the content of the thoughts. Don't pay any attention to them at all. Don't even bother saying "no". Watch. Give the thought permission to say whatever it wants to. Let the thought complete what itself. Let every bad thought happen without interference. Do not attend to them. Give yourself permission to have these thoughts. Think of these aberrant thoughts as something that is generated spontaneously by the aberrant biology of your brain. The thought is the disease talking - NOT YOU. It is an abnormal spontaneous electrical storm triggered within the brain - just like a Tourette bark is. Let it happen. Just smile and continue to do what you were doing. Don't react. You'll see that the thought by itself has no power. Watch the bad thought come and go. They just come and go when they are left alone. Watch you'll see.

I just had one: "If I were to kill my grandmother tomorrow, I would get her bequeaths sooner so that I can pay my bills." OK. So? That was interesting. Now I'll continue typing and thinking about what I want to say to you next. I know that I love my grandmother and would never kill her for the money. That's what's real. The intrusive and unwelcome thought is over. I'll probably have more. No big deal. I don't feel guilty for having these thoughts because they are not really mine. It is the illness talking - NOT YOU.


- Scott

 

Re: Must I stop my beloved Nardil????? » ace

Posted by Sad Panda on April 19, 2004, at 12:31:54

In reply to Re: Must I stop my beloved Nardil????? » Sad Panda, posted by ace on April 15, 2004, at 0:54:30

Hi Ace,

Have you tried some SSRI's, Effexor or Clomipramine?

I take it that social anxiety is a much bigger problem for you compared to OCD?

My major problem is Atypical depression. My collection of minor problems are initial insomnia, mild social anxiety, mild OCD & IBS agitated by social anxiety.

Effexor + Remeron covers most of these problems. I decided to take Effexor AFTER reading all the endless horror stories & I am glad that I did.

Cheers,
Panda

 

Re: Must I stop my beloved Nardil?????

Posted by SLS on April 19, 2004, at 14:27:02

In reply to Re: Must I stop my beloved Nardil????? » ace, posted by Sad Panda on April 19, 2004, at 12:31:54

> Hi Ace,
>
> Have you tried some SSRI's, Effexor or Clomipramine?


Yeah, Ace. It has been awhile since you listed all the things you have tried. I have been assuming that you've tried all of these drugs already.


- Scott

 

Re: Must I stop my beloved Nardil????? » Sad Panda

Posted by ace on April 20, 2004, at 1:53:43

In reply to Re: Must I stop my beloved Nardil????? » ace, posted by Sad Panda on April 19, 2004, at 12:31:54

> Hi Ace,
>
> Have you tried some SSRI's, Effexor or Clomipramine?

Yes. Zoloft was rubbish. Luvox I only lasted two days on. Anafranil I have tried 3 times. Each time i cant make it past the third day. First time, I wanted no drugs so I stopped it. SAecond time it worsened my derealization. third time it worsened my depression

But I may try it again (probably will) in the future!

>
> I take it that social anxiety is a much bigger problem for you compared to OCD?

Absolutely not. My huge two problems are OCD and phobic anxiety of depersonalization syndrome. I hate labels: overall i am a very anxious person getting caught up in obsessive thoughts. Nardil is THE drug for phobic anxiety, but works great for my dysthmia and depression too.

>
> My major problem is Atypical depression. My collection of minor problems are initial insomnia, mild social anxiety, mild OCD & IBS agitated by social anxiety.
>
> Effexor + Remeron covers most of these problems. I decided to take Effexor AFTER reading all the endless horror stories & I am glad that I did.
>
> Cheers,
> Panda

Thanks dude!

Ace.

 

Re: ATTN Scotty » SLS

Posted by ace on April 20, 2004, at 1:55:08

In reply to Re: ATTN Scotty, posted by SLS on April 19, 2004, at 6:45:26

> > Hi Andrew.
> >
> >
> > > Thanks so much Scott. I really appreciate your reply and insights.
> >
> > Just don't forget about Risperdal. I have a good feeling about this drug for you. No guarantees, of course.
> >
> > > How are you doing yourself mate?
> >
> > I've been worse.
> >
> > :-)
> >
> > You'll get there. 100%
> >
> >
> > - Scott
>
>
> Just a thought.
>
> Since there is no guarantee that Risperdal will do the trick, and you do recieve benefit from Zyprexa, it might be a reasonable strategy to try the other atypical neuroleptics as well. I would keep the Zyprexa at 5-10mg and test each drug as an add-on in the sequence you feel makes sense.
>
> - Scott
>

Thanks mate. I will do exactly this...you know me- I wont stop until i get remmision!

Andrew (Ace)

 

Re: Must I stop my beloved Nardil????? » SLS

Posted by ace on April 20, 2004, at 1:57:19

In reply to Re: Must I stop my beloved Nardil?????, posted by SLS on April 19, 2004, at 14:27:02

> > Hi Ace,
> >
> > Have you tried some SSRI's, Effexor or Clomipramine?
>
>
> Yeah, Ace. It has been awhile since you listed all the things you have tried. I have been assuming that you've tried all of these drugs already.

Preety much. But sometimes I have bailed out a little too early (no patience!)...I will generate a list soon. And yes, I think Risperidone I will trial...thanks for the support bro! You rule!

Ace

>
>
> - Scott

 

Re: ATTN Scotty » SLS

Posted by ace on April 20, 2004, at 1:58:53

In reply to Re: ATTN Scotty, posted by SLS on April 19, 2004, at 10:10:36

Scotty,
I forgot to ask...you are on the "Californian rocket fule" combo arent you???

If so, I hope you get 110% remission brother!

Your mate,
Andrew
(Ace)

 

Re: ATTN Scotty » ace

Posted by SLS on April 20, 2004, at 6:35:46

In reply to Re: ATTN Scotty » SLS, posted by ace on April 20, 2004, at 1:55:08

Hi buddy.

> > > Just don't forget about risperidone. I have a good feeling about this drug for you. No guarantees, of course.

> Thanks mate. I will do exactly this...you know me- I wont stop until i get remmision!

I know how hard it is to be patient. I myself have tended to be reactionary to anything that does not get me better quickly and has negative initial side effects. I know how easy it is to want to bail-out on a drug. I bring this up because risperidone might not feel like the right drug for you during the first week or two. In fact, you *might* feel that it makes you feel slowed-down and somewhat depressed. This usually dissipates in about a week, hopefully leaving you a future of gradual improvement. Other side effects that can occur during the first couple of weeks include mild to moderate anxiety, sedation, and dry mouth, and perhaps dizziness. Try to avoid the temptation to load up on risperidone right away. I would start out with 0.50mg a day and raise it by 0.50 every week or every two weeks to a maximum of perhaps 3.0mg. This is a moderate dosage that is commonly thought to have very little risk of developing TD. Supposedly, the threshold of increased risk is 6.0mg.

As I mentioned in a previous post, risperidone has been known to induce OCD or make it worse. However, this same phenomenon has been seen with other neuroleptics, including olanzapine. Risperidone is the most potent 5-HT2a antagonist of the neuroleptics. This action is probably a positive therapeutic attribute for some people with refractory OCD and perhaps a negative property for others. Just remember, you are not married to this drug. You can stop it anytime you want. I urge you to give it a thorough trial, and know that you are making an informed decision. I think the risk of some temporary discomfort is worth the potential benefits that risperidone offers you. If it makes your OCD dramatically worse, just discontinue it as you have other drugs to which you reacted negatively. Otherwise, try to stick it out for the first few weeks. I'll keep my fingers crossed for you. Risperidone has worked wonders for some people with refractory OCD. Keep the olanzapine for now.

Good luck!


- Scott


 

Re: ATTN Scotty » ace

Posted by SLS on April 20, 2004, at 6:41:09

In reply to Re: ATTN Scotty » SLS, posted by ace on April 20, 2004, at 1:58:53

> Scotty,

Scott :-)

> I forgot to ask...you are on the "Californian rocket fule" combo arent you???

I tried combining Remeron with Effexor 300mg, but the addition of Remeron made me feel moderately worse. I once reacted badly to a similar drug, idazoxan. It was worth the risk, though. I am trying to leave no stone unturned.


- Scott

 

Re: ATTN Scotty

Posted by Sad Panda on April 20, 2004, at 9:34:34

In reply to Re: ATTN Scotty » ace, posted by SLS on April 20, 2004, at 6:41:09

> > Scotty,
>
> Scott :-)
>
> > I forgot to ask...you are on the "Californian rocket fule" combo arent you???
>
> I tried combining Remeron with Effexor 300mg, but the addition of Remeron made me feel moderately worse. I once reacted badly to a similar drug, idazoxan. It was worth the risk, though. I am trying to leave no stone unturned.
>
>
> - Scott
>

How much Remeron were you taking? I had a bad time trying to tritate from 15mg to 30mg, Alpha-2 blockade just causes me severe irritation & crankiness. I still think of it as a good sleep pill that counters SSRI type side effects & people should only take as much as they need, rather than high dose as it is just not an effective AD for most people. I think it would be a better pill if it didn't have Alpha-2 antagonism because the 5-HT2A, 5-HT2C & 5-HT3 antagonism is great.

Cheers,
Panda.

 

Re: Must I stop my beloved Nardil????? » ace

Posted by Sad Panda on April 20, 2004, at 9:56:05

In reply to Re: Must I stop my beloved Nardil????? » Sad Panda, posted by ace on April 20, 2004, at 1:53:43

> > Hi Ace,
> >
> > Have you tried some SSRI's, Effexor or Clomipramine?
>
> Yes. Zoloft was rubbish. Luvox I only lasted two days on. Anafranil I have tried 3 times. Each time i cant make it past the third day. First time, I wanted no drugs so I stopped it. SAecond time it worsened my derealization. third time it worsened my depression
>
> But I may try it again (probably will) in the future!
>
> >
> > I take it that social anxiety is a much bigger problem for you compared to OCD?
>
> Absolutely not. My huge two problems are OCD and phobic anxiety of depersonalization syndrome. I hate labels: overall i am a very anxious person getting caught up in obsessive thoughts. Nardil is THE drug for phobic anxiety, but works great for my dysthmia and depression too.
>
>

Ooohh, I thought you had social anxiety, I don't know how I got that stuck in my head. Everything I have tried to read & absorb says you have to have an SRI to counter OCD. Patience is good to have, when I have raised the dosage of Effexor it causes me tons of anxiety in the first week or so, taking some Valium seems to take the anxiety away & leave me with some mild hypomania(overly talkative & unrealisticly good mood), after a couple of weeks I settle in an I get some good anxiolytic effect from it. I use to have a little OCD ritual before bed of going to the front door, checking that it's locked, turn power off to TV & PayTV box at wall, go to back door & check that it's locked & then head to the front door & repeat about 3-4 times before finally going to bed.(This use to drive my wife nuts!) When I was spiralling into depression & having suicide ideations countinuosly my door checking ritual was climbing upwards too. Now, with Effexor, I only do the ritual just once. If you haven't tried Effexor, I would, you just have to be prepared for possible withdrawl symptoms & have Valium onhand to counter any startup anxiety.

Cheers,
Panda.

 

Re: ATTN Scotty » Sad Panda

Posted by SLS on April 20, 2004, at 10:18:56

In reply to Re: ATTN Scotty, posted by Sad Panda on April 20, 2004, at 9:34:34

> > I tried combining Remeron with Effexor 300mg, but the addition of Remeron made me feel moderately worse. I once reacted badly to a similar drug, idazoxan. It was worth the risk, though. I am trying to leave no stone unturned.

> How much Remeron were you taking? I had a bad time trying to tritate from 15mg to 30mg, Alpha-2 blockade just causes me severe irritation & crankiness. I still think of it as a good sleep pill that counters SSRI type side effects & people should only take as much as they need, rather than high dose as it is just not an effective AD for most people. I think it would be a better pill if it didn't have Alpha-2 antagonism because the 5-HT2A, 5-HT2C & 5-HT3 antagonism is great.

I think I only made it up to 30mg. It worsened my depression at that dosage. Idazoxan is an experimental compound known to be a potent NE alpha2 antagonist. It made me feel much worse for the many weeks I was on it. I wasn't surprised when Remeron did so too.

Have you thought to try Serzone?


- Scott

 

Re: ATTN Scotty » SLS

Posted by Sad Panda on April 20, 2004, at 10:30:10

In reply to Re: ATTN Scotty » Sad Panda, posted by SLS on April 20, 2004, at 10:18:56

>
> I think I only made it up to 30mg. It worsened my depression at that dosage. Idazoxan is an experimental compound known to be a potent NE alpha2 antagonist. It made me feel much worse for the many weeks I was on it. I wasn't surprised when Remeron did so too.
>
> Have you thought to try Serzone?
>
>
> - Scott
>
>

Serzone? Did I tell you about my phobia of priapism which requires surgery to reverse? :) My understanding is it's only a 5-HT2A blocker & you get that for free in most TCA's & Remeron (& lots of AP's) Without Remeron & on Effexor only I had nausea that just never seem to go away, just 15mg got rid of my nausea totally. I really don't think I could take Effexor without Remeron, they should come mixed together at a ratio of 10:1 for me. :)

Cheers,
Panda.


 

Re: Must I stop my beloved Nardil????? » ace

Posted by luther on April 21, 2004, at 3:14:06

In reply to Must I stop my beloved Nardil?????, posted by ace on April 14, 2004, at 2:11:37

Hey Ace,
I've heard people talking about Adderall. No one is more upset that Pfizer could change Nardil, the only thing that worked for my SAD, GAD and Atypical Depression. It saved my life many years ago, now I'm back at the point where I first began, in the gutter. You might try Neurontin also.


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