Psycho-Babble Medication Thread 283363

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Re: New Version of Nardil is Working For Me

Posted by Enola on December 11, 2003, at 15:13:02

In reply to Re: New Version of Nardil is Working For Me, posted by Dave Hammond on December 11, 2003, at 1:23:53

> "My pdoc won't let me go any higher. Nothing else has worked for me. My pdoc says I need to prepare for permanent disability. Please help me."
>
> Timidly, I believe if order your Nardil from Link Pharmaceuticals in Australia, you will get the old formulation. I just e-mailed them tonight so I'm not absolutely positive about this statement, but I certainly am hoping.
>
> Note: They have not yet finished their website yet, so they are up and coming. Give them a shot.

I hate to burst your bubble here, but I obtained a bottle of Link Pharmaceutical's Nardil from xxx, a pharmacy online. It is _not_ the same as our old formulation -- it is also not the quite the same as our new formulation -- it has some components of each, but is more like our new formulation. I took it for a few days instead of the 'new' Nardil, and the side effects were just as nasty as the 'new' Nardil. They seem to work very similarly. I was extremely disappointed.

 

Re: New Version of Nardil is Working For Me

Posted by Dave Hammond on December 11, 2003, at 15:23:30

In reply to Re: New Version of Nardil is Working For Me, posted by Enola on December 11, 2003, at 15:13:02

Enola, thanks for the information. I'm not going through xxx though. I'm just about to call Link in Australia myself and find out what they have for sale.

Like you, I'm not interested in Pfizer's new formulation because the side-effect from that drug combined with the anticholinergic properties of Amitriptyline, which I also must take cause complete urinary retention in me, which is intolerable. I had to self-catheterize myself just to get to the hospital where a more permanet catheter was installed until that new drug was out of my system. Ace says he got the old formulation at Link so I thought I'd give them a try.

Thank you, of course and if this turns out to be the case Timidly, then we are in serious trouble.

 

Re: New Version of Nardil is Working For Me

Posted by enola on December 11, 2003, at 16:20:58

In reply to Re: New Version of Nardil is Working For Me, posted by Dave Hammond on December 11, 2003, at 15:23:30

> Enola, thanks for the information. I'm not going through xxx though. I'm just about to call Link in Australia myself and find out what they have for sale.
>
> Like you, I'm not interested in Pfizer's new formulation because the side-effect from that drug combined with the anticholinergic properties of Amitriptyline, which I also must take cause complete urinary retention in me, which is intolerable. I had to self-catheterize myself just to get to the hospital where a more permanet catheter was installed until that new drug was out of my system. Ace says he got the old formulation at Link so I thought I'd give them a try.
>
> Thank you, of course and if this turns out to be the case Timidly, then we are in serious trouble.

See, what I'm saying is, what I got through xxx _is_ Link's formula -- I don't believe there is any difference between what Link distributes in Europe and what they distribute in Australia -- that would be very strange. At first I thought this was possible, but here's what I believe was the cause for the mix-up: Link has not made a change to their Nardil formula because they've been making something that was different from ours _all along_. Ace has never seen what we describe as our 'old formula', being in Australia, but I am pretty positive that what I received from xxx is the same stuff that Ace has been taking all along. It just doesn't make sense any other way. However, if Link in Australia is somehow making something different from Link Europe, and it is identical to our good old Nardil, I am flying to Australia every six months, if that's what it takes, to get mine. I suppose its worth looking into, Dave, considering the stakes. I would just be really surprised.
BTW, this is your pal Tammy from anxietyhelp.org, in case you didn't know that ;)

 

Re: New Version of Nardil is Working For Me

Posted by Dave Hammond on December 11, 2003, at 16:40:09

In reply to Re: New Version of Nardil is Working For Me, posted by enola on December 11, 2003, at 16:20:58

"Link has not made a change to their Nardil formula because they've been making something that was different from ours _all along_. Ace has never seen what we describe as our 'old formula', being in Australia, but I am pretty positive that what I received from xxx is the same stuff that Ace has been taking all along."

I see, so unless there's a miracle, Link is simply selling their formulation of Nardil which is not Pfizer's "old" formulation that I've been taking for some 26 years. Well, my call did not go through, but that was my fault. I just got the prefixes and time differences in Australia figured out. It's now about 7:35 AM in Australia,
which is a bit too early to ring them. Still, I'm going to do it -- just in case.

I'm not even interested in trying the other two MAOIs, although that's why my Psychiatrist recommends. I mean what else is he going to do? Thanks for the info, Tammy. Good to see that you're still alive and kicking. If I find out that I can get the "old" Pfizer-Parke Davis Nardil from Australia I'll be certain to tell you.

Yes, the stakes are extremely high for every single one of us, except those whose systems adjust to the increased dosages the "new" Nardil requires one to take for them to be as therapeutic as the "old" Nardil.

All of this just to increase the shelf-life and dissolution rate. You bet I'd like to crown someone at Pfizer. They could at least have told us they were changing. I've not averse to freezing medications and I'd even try to freeze dry them if necessary.

Dave

 

Re: medication without a prescription » Enola

Posted by Dr. Bob on December 11, 2003, at 18:38:39

In reply to Re: New Version of Nardil is Working For Me, posted by Enola on December 11, 2003, at 15:13:02

> I obtained a bottle of Link Pharmaceutical's Nardil from xxx, a pharmacy online.

Please don't use this site to exchange information that could be used to import into the US prescription medication without a prescription:

http://www.dr-bob.org/babble/faq.html#illegal

Thanks,

Bob

 

Oops! I apologize... didn't realize.... (nm)

Posted by enola on December 11, 2003, at 19:41:18

In reply to Re: medication without a prescription » Enola, posted by Dr. Bob on December 11, 2003, at 18:38:39

 

Re: thanks (nm) » enola

Posted by Dr. Bob on December 12, 2003, at 18:08:38

In reply to Oops! I apologize... didn't realize.... (nm), posted by enola on December 11, 2003, at 19:41:18

 

Re: Nardil from Australia = 1950's version.

Posted by ace on December 15, 2003, at 5:27:17

In reply to Re: New Version of Nardil is Working For Me, posted by Enola on December 11, 2003, at 15:13:02

The Nardil from Australia is 100% Nardil. After speaking to the head director at the Link company he assured me that the Nardil is EXACTLY the same version of the one released way back in the 1950's. Hansam actually bought the rights to Nardil of Pfizer two or so years ago. Then Link, a few months ago, got the rights- it's exactly the same as Hansams version. Hansam and Link spent an extreme amount of time to get it right. It has a couple of inactive ingredients which means Nardil has to be refrigerated.

I have felt the euphoria from this Nardil- it is great.

So Australia's version is exactly the same as the 1950's first version and the Pfizer version.

It is the same as when this great med was first made- except for a couple of Inactive ingridients which have NO effect on the drugs efficacy.

 

Re: Nardil from Australia = 1950's version.

Posted by Dave Hammond on December 15, 2003, at 8:13:58

In reply to Re: Nardil from Australia = 1950's version., posted by ace on December 15, 2003, at 5:27:17

"So Australia's version is exactly the same as the 1950's first version and the Pfizer version.
It is the same as when this great med was first made- except for a couple of Inactive ingridients which have NO effect on the drugs efficacy."

The problem I've found is that they will not import their Nardil to America.


 

Re: Nardil from Australia = 1950's version.

Posted by luther on December 15, 2003, at 12:08:49

In reply to Re: Nardil from Australia = 1950's version., posted by Dave Hammond on December 15, 2003, at 8:13:58

I would be very nice to actually find the old stuff. I have tried everything with the exception of a class action law suit against Pfizer. That is my next recourse by the way. You can not change the formula of a medication and not notify you, your doctor and the pharmacist. When I made my complaint loud and clear to Pfizer I received a full refund for my Nardil prescription and didn't even ask for it! Sounds to me like they may be fearful of something, $$$ legal action. Is anyone with me? Something should and needs to be done! I'm very happy for the people in which the new Nardil works for them, I just happen not to be one of them. Unfortionatly nothing else will work for my Atypical Depression and SAD. Will I let them take away my life in the name of profits, no way! If Pfizer wants a fight they are about to get one. Like others here I thought it was possible I received a bad batch of the stuff. I tried it again just recently and got the same results, no effect, might as well been taking a placebo. For now I'm taking Parnate which is a little better than nothing at all, but not much. If anyone would like to contact me, my e-mail is: luthermeeks@peoplepc.com

 

UK Nardil is also Hansam's (old formulation)

Posted by Jonathan on December 15, 2003, at 14:28:51

In reply to Re: Nardil from Australia = 1950's version., posted by ace on December 15, 2003, at 5:27:17

but getting it is like getting the Rugby World Cup out of Australia.

 

Re: Nardil from Australia = 1950's version.

Posted by enola on December 15, 2003, at 16:28:38

In reply to Re: Nardil from Australia = 1950's version., posted by ace on December 15, 2003, at 5:27:17

Okay, Ace, I know you say this Nardil is the same, but I have reason to believe it isn't.
We may be able to answer this question definitively -- are your Nardil film-coated, or sugar-coated, like little m&m's? Our old Nardil is sugar-coated. The stuff I've seen from Europe is film-coated. You mention that the difference is a few minor inactive ingredients.. but that is the supposed difference between our old and new Nardil here, and a change in a few inactive ingredients has been what has apparently thrown our lives into turmoil over here in the US.
However, if what you have is our good old candy-coated stuff, I might have to move to AUS!

 

Re: UK Nardil is also Hansam's (old formulation)

Posted by Dave Hammond on December 15, 2003, at 18:29:11

In reply to UK Nardil is also Hansam's (old formulation), posted by Jonathan on December 15, 2003, at 14:28:51

"but getting it is like getting the Rugby World Cup out of Australia."

Besides the fact that it's not shipped into America, why is is so hard to come by?

 

Old Nardil ..... luther

Posted by maryhelen on December 16, 2003, at 8:23:25

In reply to Re: Nardil from Australia = 1950's version., posted by luther on December 15, 2003, at 12:11:12

Luther:

I have been taking Nardil since November 3rd, unaware of the controversay surrounding it. I now undersand that I am taking the old Nardil. I live in Canada. I have been getting information and help from the members at hhtp://anxietyhelp.org/treatment/medication/nardil.html They have does extensive research into the old and new Nardil and after giving them the information, which is on my bottle, determined that it is the old Nardil.

I hope this is helpful.

maryhelen

 

Pfizer/FDA contact info - NARDIL NOT WORKING!

Posted by strat on January 6, 2004, at 9:25:33

In reply to Old Nardil ..... luther, posted by maryhelen on December 16, 2003, at 8:23:25

Am I ever glad I found you folks. Just went through an horrific anxiety attack in mid-December after 20 days on the new formula. I also don't want to go through the horror of finding a new anti-depressant!!!

As to the actual compression/coating of the 'new' pill - anyone else experience the taste of this 'new' formulation? I usually pop my meds in my mouth in the morning then go off in search of water.

Yecch - this new one dissolves immediately and has a taste I can only describe as 'skunk-like'.

Are there any other boards that folks have found to post on, as well as this one?

I find when upping the dosage I feel more giddy than un-depressed. (upped from 2 to 3-15mg per day).

I've both called Pfizer and contacted the FDA and filled out the FDA's Medwatch form online. Pfizer told me same - that they'd changed the 'inactive ingredients' to prolong shelf-life.

Also, I've read the 'permission granted' on the FDA site - apparently there were no control tests on this 'new' medication - they simply removed the word 'corn starch' from the labeling and added a few blurbs. Seems to me they were somehow misrepresenting the actual changes.

MEDWATCH FORM:

http://www.fda.gov/medwatch/

Here are all the phone numbers I have

PFIZER
1-212-573-2323
1-800-332-1240
PFIZER/PARKE-DAVIS
1-800-223-0432
973-385-2000

I got MORE info from them HERE than at the above phone number:

1-800-438-1985

Hope this helps. PLEASE call these folks and report. I heard from Pfizer that a physician had also called to inquire about a patient that had a similar experience.

 

Re: Pfizer/FDA contact info - NARDIL NOT WORKING!

Posted by Dave Hammond on January 6, 2004, at 12:22:58

In reply to Pfizer/FDA contact info - NARDIL NOT WORKING!, posted by strat on January 6, 2004, at 9:25:33

"Am I ever glad I found you folks. Just went through an horrific anxiety attack in mid-December after 20 days on the new formula. I also don't want to go through the horror of finding a new anti-depressant!!!"

You might not have to. Have you increased your dosage, yet and are you taking anything else in conjunction with the "new" Nardil?

"As to the actual compression/coating of the 'new' pill - anyone else experience the taste of this 'new' formulation? I usually pop my meds in my mouth in the morning then go off in search of water."

I never wait that long. I always have something to drink to down my meds. I take one that would dissolve too quickly, and so I cannot risk it.

"Yecch - this new one dissolves immediately and has a taste I can only describe as 'skunk-like'."

Do not allow it to dissolve in your mouth. This one is no longer coated as I'm certain you've noticed.

"Are there any other boards that folks have found to post on, as well as this one?"

Yes, there's an Anxiety board and a couple of other less helpful ones that I've found.

"I find when upping the dosage I feel more giddy than un-depressed. (upped from 2 to 3-15mg per day)."

You are going to go through some changes here with side-effects that could last as long a 4 months. If this "newer' formulation helps you, then by all means stick with it. Otherwise, well, I suppose you already know what your options are or you soon will.

"I've both called Pfizer and contacted the FDA and filled out the FDA's Medwatch form online. Pfizer told me same - that they'd changed the 'inactive ingredients' to prolong shelf-life."

Okay, the inactive ingredients (expients) actually determine how your body metabolizes this medication. So when they change that, they are changing everything.

"Also, I've read the 'permission granted' on the FDA site - apparently there were no control tests on this 'new' medication - they simply removed the word 'corn starch' from the labeling and added a few blurbs. Seems to me they were somehow misrepresenting the actual changes."

There are six changes in expients between what Pfizer used to make and what it makes today. That's why it's metabolized differently than the "old" Nardil was.

 

strat .........e-mail address for anxiety board

Posted by maryhelen on January 6, 2004, at 20:33:09

In reply to Pfizer/FDA contact info - NARDIL NOT WORKING!, posted by strat on January 6, 2004, at 9:25:33

Hi Strat:

The email address for the anxiety board is in my post. This is an excellent site to go back and follow the discovery (by patients of course, not doctors or pharmacists) of the changes made to Nardil. I don't know if I am coming or going. My pharmacist is going to get the Pfizer rep to come in.

I just started taking the old Nardil on November 3rd

 

Re: strat .........e-mail address for anxiety board

Posted by strat on January 7, 2004, at 6:15:57

In reply to strat .........e-mail address for anxiety board, posted by maryhelen on January 6, 2004, at 20:33:09

Thanks, MaryHelen, for another good idea. I've used the same pharmacist for years; I'll ask him to do same. I found the anxiety board; have already posted there!

Pierre, thanks for the nod of approval! I appreciate having the support here!

Strat

 

Re: COMPAINTS REGARDING NEW NARDIL

Posted by jlbl2l on January 7, 2004, at 16:32:50

In reply to COMPAINTS REGARDING NEW NARDIL, posted by ace on November 24, 2003, at 18:59:51

Hello, I am new here, and just started Nardil for social phobia a few days ago. Mine is the UK Nardil by Hansam. The ingredients list as :

phenelzine sulphate 15mg BP, inactive : mannitol and sunset yellow FCF.

It is districuted by Link Pharmeceticals Limited. The pills are small and red and do dissolve quite quickly and taste bad. No benefits yet...

 

Re: COMP(L)AINTS REGARDING NEW NARDIL

Posted by strat on January 7, 2004, at 16:50:08

In reply to Re: COMPAINTS REGARDING NEW NARDIL, posted by jlbl2l on January 7, 2004, at 16:32:50

In response to your post, jlbl21, this sounds to me like the 'new' Nardil. Take your time, see how it feels.... some folks who start out on the 'new' one seem to do just fine. It is those of us who took the 'old' one and are now taking the 'new' one that seem to be the ones mainly having difficulties.

Don't be afraid to report any difficulties to the person who prescribed this to you. Naturally, you're probably very concerned... especially since you've just started.

There's also a great board to post on/read on here:
http://www.anxietyhelp.org/treatment/medication/nardil.html

As I mentioned, not all of us are having big struggles.... just keep reading, keep learning, keep talking to your medical professional, and ask questions!

We're with you....

--strat

 

Re: COMP(L)AINTS REGARDING NEW NARDIL

Posted by jlbl2l on January 7, 2004, at 17:16:48

In reply to Re: COMP(L)AINTS REGARDING NEW NARDIL, posted by strat on January 7, 2004, at 16:50:08

thanks! yeah so far few side effects or good ones. i have a medalert id bracelet, diet restrictions list, blood pressure monitor and nifedipine that i was given. im starting at 60/mg a day split between every 6 hours or so. (15mg tablets)

 

Re: COMP(L)AINTS REGARDING NEW NARDIL

Posted by gardenergirl on January 7, 2004, at 19:46:25

In reply to Re: COMP(L)AINTS REGARDING NEW NARDIL, posted by jlbl2l on January 7, 2004, at 17:16:48

FYI, I started on the new Nardil, and I have not had any of the problems those that were on the old did. I guess I'm glad I avoided all that, but I feel for those who are coping with the change.

Good luck to all on Nardil! It takes extra strong coping to deal with the SE's and the diet. I applaud all of us.
g

 

Re: COMP(L)AINTS REGARDING NEW NARDIL

Posted by strat on January 7, 2004, at 20:08:48

In reply to Re: COMP(L)AINTS REGARDING NEW NARDIL, posted by gardenergirl on January 7, 2004, at 19:46:25

jlbl:

Good on you for having the medalert bracelet! I'm forever telling dentists 'NO epinephrine!!!' (they have another novocain that doesn't contain it...)

I'm quite accustomed to the restrictions. However, after a bit, I dropped from 60mg (which was too much for me - plunged me back into a crying state/depression) to 45 mg... then eventually, (for years now) 30 mg. I eat cheese, ham, bacon, coffee (no booze at all, because I choose not to drink) and everything I want. Once you're stabilized and have been taking it for awhile, and are maybe on a lower dosage, you may not have to deal with all the restrictions. (BUT! I'm NOT a professional, and am NOT recommending this.) I just had pizza one day without thinking about it, about a year after I started Nardil, and it was fine.

gardenergirl: I'm doing better on the new stuff, too, although I note edema and sleepiness. I'm glad to hear you're doing okay! Haven't had a panic attack again since the 'transition time' (about 20 days after I started the new version) when I felt like I was actually withdrawing from the old. Sharing this because if it happens to others, I want to offer my reassurance that it will pass. :D

jlbl:

If you're in Canada, or outside the U.S. you may just be lucky enough to be able to continue to take the 'old' version. I've heard others on the board here say that this is predominantly a U.S. problem...

Nice thing about Nardil, for me, when I first started, was that it almost IMMEDIATELY took care of my panic attacks. Like, the first day or two. :D

That's nice.

Warmly, to both of you -
strat

 

Re: COMP(L)AINTS REGARDING NEW NARDIL

Posted by shytilwet on January 8, 2004, at 8:25:34

In reply to Re: COMP(L)AINTS REGARDING NEW NARDIL, posted by strat on January 7, 2004, at 20:08:48

I was told Nardil had been discontinued by the manufacturer, and is no longer available in Australia.
Does anyone know if this is true or how I can find out, please?

 

Re: COMP(L)AINTS REGARDING NEW NARDIL

Posted by Dave Hammond on January 8, 2004, at 11:06:16

In reply to Re: COMP(L)AINTS REGARDING NEW NARDIL, posted by shytilwet on January 8, 2004, at 8:25:34

"I was told Nardil had been discontinued by the manufacturer, and is no longer available in Australia. Does anyone know if this is true or how I can find out, please?"

Link Pharmaceuticals sells some form of Nardil in Australia. I believe it's hybrid between the "old" and the "new" forms of Nardil that Pfizer Park Davis makes, but I have not yet been able to establish this with exact specificity, because the indivdual who is trying to find this out for me does not understand how buffering agents work at all. In his world one could put 15 mg of Phenezline Sulfate into water and it would be metabolized the same way as it is taking any in tablet form.


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