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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by jonh kimble on April 7, 2003, at 21:28:14
has anybody had a reduced stimulant tolerance while on a mood stabilizer? theoretically they would, as excess glutamate and asparate are supposed to increase tolerance, and i think i am noticing a minor decrease on 37.5 lamictal. any reports or info would be great.
Posted by jaby on April 8, 2003, at 11:04:10
In reply to mood stabilizers and stim tolerance, posted by jonh kimble on April 7, 2003, at 21:28:14
I think you're more likely too just be experiencing the stimulating effect of lamictal
Posted by jonh kimble on April 8, 2003, at 17:34:13
In reply to Re: mood stabilizers and stim tolerance, posted by jaby on April 8, 2003, at 11:04:10
Posted by jaby on April 8, 2003, at 18:36:14
In reply to Re: what is lamictals mode of ad action? (nm), posted by jonh kimble on April 8, 2003, at 17:34:13
I'm not certain (not sure if anyone is). It blocks sodium channels which inhibits the nmda receptor's glutamate release. I think it also has an afinity for calcium channels as well (probably also effecting the nmda recptor). It increases GABA-A levels also.
That's about all I know. It is avery energizing meds for me. Hope it works out well for you.
Posted by Peter S. on April 10, 2003, at 16:37:55
In reply to Re: what is lamictals mode of ad action?, posted by jaby on April 8, 2003, at 18:36:14
Lamictal is very strange in its effect on me. About an hour after I take it I get a great boost in energy and lowering of depression. This generally lasts till late afternoon and then fades away.
I have read nothing about Lamictal that would explain this, but I know that it's more than just a mood stabilizer. Anyone know what might explain these effects?
> I'm not certain (not sure if anyone is). It blocks sodium channels which inhibits the nmda receptor's glutamate release. I think it also has an afinity for calcium channels as well (probably also effecting the nmda recptor). It increases GABA-A levels also.
>
> That's about all I know. It is avery energizing meds for me. Hope it works out well for you.
This is the end of the thread.
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