Psycho-Babble Medication Thread 75408

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Re: side effects of MAOI's

Posted by jsarirose on October 2, 2002, at 16:10:53

In reply to side effects of MAOI's Bobbiedobbs, posted by katie tkm on October 2, 2002, at 10:41:57

> Would you guys (and anyone else) mind telling me about your side effects on different MAOI's? I know it's a bit personal so I don't mind if you don't want to.
>

Parnate isn't known to have a negative sexual side effect, in fact it usually increases sex drive. For me, it has had that effect (not a bad thing unless you have no one to share that increased drive with!).

As for negative side effects, for me, my acne has gotten pretty bad with Parnate. There are of course the dietary restrictions, which I won't go into since you know about them. I am occasionally dizzy and have to pause when standing quickly from a sitting or prone position. I have trouble sleeping, but I take Trazodone for that so it actually doesn't effect me too much.

Those are the main negatives for me. The dizziness isn't a big deal. The worst for me is the acne (and of course diet restrictions). But the benefit I've gained from Parnate greatly out weighs any downsides. Oh, and I've also lost a lot of weight. It helps control my cravings and compulsive eating. It also controls my appetite. I've been able to start eating much healthier and lose weight while on Parnate.

So - I think that's it for me! I've never taken Nardil so I don't know how it compares. I do know my doctor chose Parnate because of the weight issue (it doesn't promote weight gain) and the (non) sexual side effects.

-Jessica

 

Re: side effects of MAOI's

Posted by Bobbiedobbs on October 2, 2002, at 22:26:37

In reply to Re: side effects of MAOI's, posted by jsarirose on October 2, 2002, at 16:10:53

Hi - I can't write anything coherent tonight as I'm too harried and stressed out but will try to send you something that may be helpful tomorrow - I actually know (in person, no less!) a couple of people who have taken Nardil in the past (besides myself.
BTW, Jess, my doctor tells me trazadone is contraindicative to Parnate. Also, the acne is listed as a "reported" side effect to Parnate in the manufacturer's material. Phil

 

Re: side effects of MAOI's jsarirose

Posted by katie tkm on October 2, 2002, at 23:23:24

In reply to Re: side effects of MAOI's, posted by jsarirose on October 2, 2002, at 16:10:53

thanks for info jess, hope acne improves.

and phil - hope you feel better soon buddy

x katie

 

Re: side effects of MAOI's

Posted by jsarirose on October 3, 2002, at 1:44:51

In reply to Re: side effects of MAOI's, posted by Bobbiedobbs on October 2, 2002, at 22:26:37

> BTW, Jess, my doctor tells me trazadone is contraindicative to Parnate. Also, the acne is listed as a "reported" side effect to Parnate in the manufacturer's material. Phil

Yeah, there are actually quite a few drugs that are contraindicative to Parnate that doctors are now prescribing. Once again, I think the pharmaceutical companies are extremely conservative to avoid lawsuits. But if you look at actual practice vs. theory, many 'taboo' drugs work just fine with Parnate. Of course I would absolutely only take something with a doctor's guidance. I've heard of others taking Trazodone too. I think if the doctor is monitoring closely, it's okay to try.

-Jessica (my two cents!)

 

Re: side effects of MAOI's

Posted by Bobbiedobbs on October 4, 2002, at 0:30:34

In reply to Re: side effects of MAOI's, posted by jsarirose on October 3, 2002, at 1:44:51

Katie:
Nardil worked like a charm for me in relieving (or at least mitigating) my social inhibition and anxiety. The bummer was the side effects at 60 mg and higher. These included insomnia (this did get better over time),intermittent constipation, "urinary retention" (or to put it crudely, difficulty taking a piss), difficulty maintaining an erection and, at 60 mg, a complete inability to reach orgasm. These symptoms would show up beginning at about 45 mg. and whop me at 60 mg. (They weren't much of a problem at lower doseages).I put up with all this because I felt more comfortable socially, less anxious and inhibited and generally better able to function (well, at least socially.) I would drop the med level down to get relief.
After a few years, the side effects worsened while the benefits diminished. I switched to Parnate, which I've taken for the past two years. P. has been a different beast altogether. Its side effects are less acute but it also has less of a kick. It doesn't appear to cause weight gain, as did Nardil. However, I'm taking naps during the day and, at 40 mg. or higher, have to put up with the aforementioned constipation and anorgasmia.
That said, from what I've heard and read, the two medications seem to act differently on different individuals. Some people get hyper on Parnate, others are fatigued. But some of the things you mentioned I'd say are common complaints, particularly with Nardil.
I should add that some of the initial side effects which I experienced with Nardil dropped off after a few weeks. These included dizziness (particularly upon going from reclining to standing) dry mouth, shakies (leg shaking - quite the turn-on!) and sleeping difficulty.
You might consider giving the Nardil awhile longer, dropping the level down when the side effects became harder to tolerable. There is supposed to be some retained benefit from an initial higher dose followed by a maintenance level. If the problems continue, I'd give Parnate a try, as the MAOs appear efficacious for you.
Hope this helps. At least we can eat certain kinds of cheese and drink bottled beer. Best wishes, Phil.

 

Re: side effects of MAOI's

Posted by jsarirose on October 4, 2002, at 13:38:01

In reply to Re: side effects of MAOI's, posted by Bobbiedobbs on October 4, 2002, at 0:30:34

> Hope this helps. At least we can eat certain kinds of cheese and drink bottled beer. Best wishes, Phil.

Is the dietary restriction for Nardil different from Parnate? I didn't know that. I thought it was the same for all MAOI's.

As Phil said, the side effects seem to vary for different people. I was hoping Cyberspace would jump in here too. I believe he had the same elevated sex drive that I had (have). And I believe insomnia is more common than sleepiness - in general of course. There are a few people that seem to have a great intolerance for the drug. Even 10 or 20mg seems to be extremely difficult on their system. For myself, I was taking up to 100mg with the only increased side effects being more dizziness at times, more insomnia (but I take Trazodone as stated before), increased acne, and increased sex drive, which is a negative if you're single. : )

It sounds like YMMV (Your Mileage May Vary) is very true on Parnate.

-Jessica

ps - It just occurred to me, but I wonder if anyone has ever done any studies about differences in side effects for males vs females. I wonder if there are any differences based on sex.

 

Re: side effects of MAOI's

Posted by ayrity on October 5, 2002, at 0:41:35

In reply to Re: side effects of MAOI's, posted by jsarirose on October 4, 2002, at 13:38:01

Well, I'm on 70 mg of Parnate now for several weeks. Still having occassional bad blood pressure spikes after a dose, not related to food, and unpredictable (some days, BP fine; other days, BP through the roof after a dose). I can't seem to tolerate more than 20 mg at a time, but as we go up on the dose I can't keep spreading the doses out all day or I'll be popping pills like crazy! If things aren't better soon, we might try Marplan.

As far as other side effects on the Parnate, I've had a really bad taste in my mouth for a while now. Anyone else have that problem?

Also, sleepy during the day; insomnia at night (but I had that beforehand as well).

A bit of an effect on orgasm now at 70 mg- not delayed or anorgasmic, just much less intense.

A bit of dizziness at times on standing suddenly, but that hasn't been too bad.

My mood's a bit better, and I feel a bit more "chatty" with strangers, but this has not been dramatic enough to justify the side effects so far. Ah well.... Drug resistent depression sucks.

 

Re: side effects of MAOI's

Posted by Bobbiedobbs on October 5, 2002, at 1:17:26

In reply to Re: side effects of MAOI's, posted by ayrity on October 5, 2002, at 0:41:35

Jessica - To answer your question, I don't think there is any inherent difference in food restrictions between the Nardil and Parnate except to the extent that they may act differently on different individuals.
My remark on the beer and cheese was meant to apply to MAOs generally.
I share the same characteristic of the last poster vis a vis Parnate (and Nardil) - sleepy during the day and up at night. Both of these medications - Nardil in particular - reved up my sex drive (and pursuit of partners) The problem was at high doses I was restricted in my range of fulfillment options. It did make for greater creativity. Some of you folks may have a greater tolerance for higher doses generally. I haven't pushed Parnate beyond 50 mg. Phil

 

Re: side effects of MAOI's

Posted by jsarirose on October 5, 2002, at 1:50:19

In reply to Re: side effects of MAOI's, posted by Bobbiedobbs on October 5, 2002, at 1:17:26

> Jessica - To answer your question, I don't think there is any inherent difference in food restrictions between the Nardil and Parnate except to the extent that they may act differently on different individuals.
> My remark on the beer and cheese was meant to apply to MAOs generally.
> I share the same characteristic of the last poster vis a vis Parnate (and Nardil) - sleepy during the day and up at night. Both of these medications - Nardil in particular - reved up my sex drive (and pursuit of partners) The problem was at high doses I was restricted in my range of fulfillment options. It did make for greater creativity. Some of you folks may have a greater tolerance for higher doses generally. I haven't pushed Parnate beyond 50 mg. Phil
>

Thanks for the clarification. I definitely know the some people seem to be med sensitive and others are med resistant. I almost always have to take the highest dose of meds. My sister takes less than a "medicinal" dosage of her med and does fine.

For those of you with "Treatment Resistant Depression", here's a great site. It outlines the suggested med route for TRD. My doctor has followed the suggestions (on her own) which gave me renewed faith in her.

http://www.acnp.org/g4/GN401000105/Default.htm

-Jessica

 

Re: side effects of MAOI's yeast extract jsarirose

Posted by katie tkm on October 5, 2002, at 3:57:21

In reply to Re: side effects of MAOI's, posted by jsarirose on October 5, 2002, at 1:50:19

god, it's interesting how these side effects are different for all of us. there are some similarities and i must say knowing what others have experienced is reassuring.

i'm doing my best not to get excited (because i have recurrent depression which has gone into spontaneous remission several times) but Nardil is the first drug which has ever worked for me. i could actually feel it lifting the depression/anxiety.

reading this bulletin board was great because it helped me stick out the horror side effects which have mostly faded now. the pros vs cons are definitely worth it for me at the moment and i cannot describe the relief of discovering my "self" and my capabilities again. it's something i dearly wish for everyone who's experienced severe depression - no one who's not been through it can know what it's like.

i wouldn't say i'm completely magically recovered but the difference in the last few weeks is pretty amazing. i'm taking life slow and gently and not expecting too much at this stage. only time will tell how the medication and remaining side effects pan out. i'm hoping i may be well enough to return to study next year.

i've said thanks a million times but i am so grateful for the people and the info on this board. it's made a difference. the maoi diets drs/drug companies/pharmacies still hand out (and most of the diets on the web) are terribly restrictive. i was willing to take it because the depression was so bad but the info on this site has shown me i don't really have to change my lifestyle that much. i can still drink and eat out!

**jess, did you notice on that virtual hospital article you pointed me to there are direct contradictions on diet? the info was excellent but on page 4 it says you can't have yeast extracts (or pickled herring) and in table 7 on page 11 it says you can have both. i'm particularly interested in yeast extracts because i love sauce so much. anyway, i thought i'd better try to find the original articles they reference to get the lowdown. if anyone knows more please let me know.

i just wanted to say "why the fuck don't doctors prescribe MAOI's anymore!!?" i know they're scared but i really had to convince my pdoc and MAOI'S seem to be the answer for me. the MAOI bad rep needs to change. reading the postings makes me realise that others have waited much more than 3 yrs, 4 pdocs and 8 medications looking for a drug that works (and some are still looking). but i wish this had been tried ages ago!!!

best wishes
katie

 

Re: please be civil katie tkm

Posted by Dr. Bob on October 5, 2002, at 13:18:29

In reply to Re: side effects of MAOI's yeast extract jsarirose, posted by katie tkm on October 5, 2002, at 3:57:21

> i just wanted to say "why the f*** don't doctors prescribe MAOI's anymore!!?"

I understand it's frustrating, but please don't use language that could offend others:

http://www.dr-bob.org/babble/faq.html#civil

Thanks,

Bob

PS: Follow-ups regarding posting policies, and complaints about posts, should be redirected to Psycho-Babble Administration.

 

Re: Dr. Bob : as Dr. your MAOI vs SSRI?

Posted by polarbear206 on October 5, 2002, at 16:09:54

In reply to Dr. Bob : as Dr. your MAOI vs SSRI?, posted by chad_3 on October 5, 2002, at 14:09:51

> I return only for this post ...
>
> Was curious Dr. Bob how often your prescribe MAOI's. As you know, expert psychiatrists consider these considerably underutilized. And latest consenses is that MAOI's have less sexual side effects than SSRI's in general.
>
> I personally feel the post was not offensive - I felt she spoke honestly and sounded compassionate and caring...
>
> My input,
>
> Chad
> http://www.socialfear.com/
>
>
>
> > > i just wanted to say "why the f*** don't doctors prescribe MAOI's anymore!!?"
> >
> > I understand it's frustrating, but please don't use language that could offend others:
> >
> > http://www.dr-bob.org/babble/faq.html#civil
> >
> > Thanks,
> >
> > Bob
> >
> > PS: Follow-ups regarding posting policies, and complaints about posts, should be redirected to Psycho-Babble Administration.
>
>


In my own opinion and from my experience, the older drugs (MAOI'S and Tricyclics) are far more
superior to the newer generation of antidepressants. Esp. for those with atypical/vegitated and more severe forms of endogenous dperessions. They are refered by many p-doc's as "OLD FAITHFULS".

Laura.

 

Re: Follow-ups regarding posting policies

Posted by Dr. Bob on October 6, 2002, at 11:55:29

In reply to Re: please be civil katie tkm, posted by Dr. Bob on October 5, 2002, at 13:18:29

> PS: Follow-ups regarding posting policies, and complaints about posts, should be redirected to Psycho-Babble Administration.

Here's a link:

http://www.dr-bob.org/babble/admin/20020918/msgs/7669.html

Sorry, but some discussion about medication got moved along with that about posting policies...

Bob

 

Re: Back to MAOIs

Posted by jsarirose on October 6, 2002, at 17:20:31

In reply to Re: Follow-ups regarding posting policies, posted by Dr. Bob on October 6, 2002, at 11:55:29

(I'll skip the posting issue.)

Katie - I kind of understand why MAOI's are a later, not first choice, but I totally agree that they shouldn't wait so long to try them. I've been through so many years of depression and failed drug attempts (legal) and Parnate is the first thing in ages to help me. I felt/feel like you! I'm so excited to actually have some relief and perhaps start thinking about a future again. It's a little scary to trust it, but I, too, am just going slowly and trying to enjoy.

Regarding the MAOI diet lists on the site I mentioned (http://www.vh.org/Providers/Conferences/CPS/19.html), they actually aren't completely inconsistent. For the yeast extract it lists specifically Marmite as having a very high tyramine count, and later it mentions that yeast extract is okay except for Marmite. The herring it first states has a level of 2.45 per serving which is within aceptable levels unless a great amount is eaten. Then later it lists it as an acceptable food. I agree that it is a bit contradictory about whether it is unlimited or not. My take is that based on the tyramine level listed, it's okay in limited amounts. Completely my opinion though!

Let me know if you are still confused! (It's not easy...) And I also agree that this site is great. I've learned so much from everyone here.

-Jessica

 

Re: please be civil Dr. Bob

Posted by katie tkm on October 6, 2002, at 21:11:55

In reply to Re: please be civil katie tkm, posted by Dr. Bob on October 5, 2002, at 13:18:29

dear dr bob,

i sincerely apologise to you and to anyone who was offended by my comment.

this board has been an invaluable support to me.

the word is in common usage, but i understand how not commenting on one instance could lead to a storm of even worse language on the board.

i'm not a big swearer in general - i wanted to emphasize a point and unfortunately f*** clearly expressed the depth of my emotion!!!

next time i will just have to use many exclamation points.

thank you to other postings for understanding why i expressed myself as i did.

apologies
katie

p.s. do you check these postings personally dr bob? or do graduate students? it seems like a large job for one person.


> > i just wanted to say "why the f*** don't doctors prescribe MAOI's anymore!!?"
>
> I understand it's frustrating, but please don't use language that could offend others:
>
> http://www.dr-bob.org/babble/faq.html#civil
>
> Thanks,
>
> Bob
>
> PS: Follow-ups regarding posting policies, and complaints about posts, should be redirected to Psycho-Babble Administration.

 

accumulating tyramine jsarirose

Posted by katie tkm on October 6, 2002, at 22:14:25

In reply to Re: Back to MAOIs, posted by jsarirose on October 6, 2002, at 17:20:31

dear jess,

thanks for your post and understanding. please read my previous email for apology for any offense i may have caused.

i'm trying to find a post i thought you wrote a while ago (i could have been mistaken thinking i'd seen your name). i've found negotiating all the threads a bit difficult and confusing at times. i've also read so much it gets mixed up in my overloaded brain! but i'm sure i came across a post you wrote about research into how long tyramine stays in the body. i just can't find it again.

did you write it? could i please get the link off you again?

thanks
katie

p.s. i'm really glad MAOI's are giving you some relief too.

 

Re: accumulating tyramine

Posted by jsarirose on October 7, 2002, at 13:45:42

In reply to accumulating tyramine jsarirose, posted by katie tkm on October 6, 2002, at 22:14:25

> dear jess,
>
> thanks for your post and understanding. please read my previous email for apology for any offense i may have caused.
>
> i'm trying to find a post i thought you wrote a while ago (i could have been mistaken thinking i'd seen your name). i've found negotiating all the threads a bit difficult and confusing at times. i've also read so much it gets mixed up in my overloaded brain! but i'm sure i came across a post you wrote about research into how long tyramine stays in the body. i just can't find it again.
>

I can't recall where I found the information, but I can tell you what I remember. When I have more time later I'll see if I can find it again. Basically it fades from your body and by 12 hours is gone. So if you have 6 shots of espresso at once it's going to be more harmful than one shot every two hours for 12 hours. I don't think I found an exact formula - but I'll check on it.

-Jessica
ps - I was not offended in the least by your post, but I understand the need for rules. (The part of my last post pertaining to the posting issue was removed because the whole message seemed to be blocked if I included it.)

 

Re: thanks for understanding (nm) katie tkm

Posted by Dr. Bob on October 7, 2002, at 17:52:28

In reply to Re: please be civil Dr. Bob, posted by katie tkm on October 6, 2002, at 21:11:55

 

New to MAOIs

Posted by eln on October 11, 2002, at 16:40:23

In reply to Re: thanks for understanding (nm) katie tkm, posted by Dr. Bob on October 7, 2002, at 17:52:28

Hi all-
I have been reading through your correspondence on this thread, and have found the suggestions very helpful. Currently, I am on a 10-day tapering off period for my antidepressants. In about 3 weeks, I will be starting on Parnate.

I have a few questions about the diet, drug restrictions, and such. I have a pshychiatrist who is pretty good, but a little ill-informed about the more recent discoveries about "safe" foods and hypertensive crisis medications.

1. He suggested that I get a medic alert-type bracelet. I want to get a remotely fashionable one, so I need to get it inscribed with a short description rather than a phone number to call.
What should I have engraved on it? (I have 36 characters)

2. There are a few foods which I am not sure are "safe" at all or not:
- pickles (Kosher dill)
- Campbell's soup
- Malt beverages (like Skyy Blue, Smirnoff Ice)
- Thai food (curries)
- Aspartame (like in Diet Coke)
- Vegetarian frozen products (Morningstar Farms products)

3. Which "emergency" medication/s should I ask for? Should I also ask for pain medication in case of a severe migraine?


Thanks in advance,
E


 

Re: New to MAOIs

Posted by jsarirose on October 11, 2002, at 19:12:09

In reply to New to MAOIs, posted by eln on October 11, 2002, at 16:40:23

> 1. He suggested that I get a medic alert-type bracelet. I want to get a remotely fashionable one, so I need to get it inscribed with a short description rather than a phone number to call.
> What should I have engraved on it? (I have 36 characters)
>
> 2. There are a few foods which I am not sure are "safe" at all or not:
> - pickles (Kosher dill)
> - Campbell's soup
> - Malt beverages (like Skyy Blue, Smirnoff Ice)
> - Thai food (curries)
> - Aspartame (like in Diet Coke)
> - Vegetarian frozen products (Morningstar Farms products)
>
> 3. Which "emergency" medication/s should I ask for? Should I also ask for pain medication in case of a severe migraine?
>
>
> Thanks in advance,
> E
>
Okay - I'll go first. : )

1. I don't know. I keep a slip of paper in my wallet on the hunch that if I'm in an accident and can't communicate they'll check for ID and find the paper. It lists all my current meds, the dosage, which pills I will have taken in a hypertensive crisis, and my psychiatrist's phone number.

2.
Pickles - just fine (& yummy!)

Campbell's Soup - depends, check for autolyzed yeast in the ingredients and any obvious taboo's (cheese, etc.)

Bottled (as opposed to tap) malt beverages - Fine. You may want to stick to larger companies (like those you mentioned) and not tiny local breweries. Also, it is considered a moderate item, meaning I wouldn't recommend a whole ton of beer or malt beverage. Although several people on this list have had a fair amount with no ill effects (including me). Parnate tends to make me more sensitive to alcohol as well. I get much more of an effect from less alcohol, so be careful the first time you drink. I don't know if other people have had the same tolerance reaction.

Thai Food - be careful, make sure you know what's in it, or at least ask about the amount of soy sauce, whether it contains fermented soy or tempeh, and if it contains any fish or shrimp paste. I eat Asian foods, but try to stick to more obvious items unless the waitperson has a good grasp of English and I can ask them about ingredients. Curry itself is just fine if you're talking about cumin & coriander, which are the main ingredients. You may want to pick up a bottle at the store and check the ingredients, I would guess it's just fine.

Aspartame - no problem

Vegetarian Frozen Products - again, you need to check for autolyzed yeast, marmite, or any obvious taboo foods. I've had better luck with the vegetarian, organic, or more natural foods. The general ones such as Budget Gourmet, etc. tend to contain autolyzed yeast.

And a final point about autolyzed yeast. It's listed as not allowable, but I have eaten some products that contain it with no adverse effects. My guess is the amount is so tiny that it's okay - but I don't eat it any more because I really don't want to trigger an episode. So I stick to the list (newer).

3. There are many pills that people use. My personal favorite is the one my doctor gave me because it is safe to take even if your blood pressure isn't spiking. It's not always possible to take your blood pressure when you're in the middle of an attack. I take Chlorpromazine (Thorazine). It will bring down my blood pressure if it's elevated, but if it's not elevated it still helps alleviate my migraine. It does make you tired for a day or two. And I also tend to feel dizzy for a day or two. I'm not sure if those symptoms are from the Thorazine or the crisis though. I only have to take one pill. I keep one with me in my wallet, one in my car, and a few at home. I also take 1/2 to a whole Oxycodone. I have these left over from surgery though, I don't know if my doctor would prescribe some or not. The pain of migraine is so intense that the Oxycodone really helps. I've had three attacks so far in about a year. The first two were early on due to eating mistakes. I don't think my blood pressure elevated but I did get an intense migraine. The third was recent (and totally my fault, I had beer on tap knowing better), my blood pressure definitely spiked as I became sweaty, nauseas and dizzy. I took my pill immediately as I recognized the onset of symptoms and it was my most mild migraine. Then I'm just left with being tired, dizzy, and mildly headachy.

I don't want to scare you with my descriptions of the attacks - if you're careful you should be able to avoid them. And if you make a mistake, it won't last forever. I never had to go to the hospital, I never saw my doctor, I just took my emergency pill and rested at home. Some of the other pills are more serious and are only okay if your blood pressure is spiking. Also some require you to go to the hospital. I think this is unnecessary.

Well, good luck. Feel free to email if you need moral support or have more questions.

-Jessica (jsarirose@attbi.com)

 

Re: New to MAOIs

Posted by cybercafe on October 13, 2002, at 11:46:34

In reply to Re: New to MAOIs, posted by jsarirose on October 11, 2002, at 19:12:09


Hey jess I just paid another visit to sunnybrook and they have quite a stash of psychiatric journals... "Tyramine content of preserved and fermented foods or condiments of Far Eastern Cuisine" is my latest find .... apparently the author found a portion of malaysian curry to have 2.88 mg of tyramine .... fried noodles to have 2.12 .... and chicken/coconut sauce to have 6.31 ... thai sausages 2.03 ... chicken bamboo curry 1.69 ... glass noodles with mushrooms 3.36 ... sweet and sour beef 2.18 ...and korean beer was a real killer, at 13.97

so it's all quite complicated... like, if you are in the east, and go to a small restaurant, and eat a big portion you could be headed for trouble..... but otherwise you're probably safe??

 

maoi and tyrosine

Posted by Ted Abel on October 13, 2002, at 11:50:21

In reply to Re: New to MAOIs, posted by jsarirose on October 11, 2002, at 19:12:09

I have been on nardil for almost seven years. At first it was wonderful; literally saving my life, or atleast starting it again.I am starting to get a decreased benefit. Due to side-effects, I can't increase the dose.
I heard that tyrosine acts as a precursor to the necessary neurotransmitters, especially dopamine. But I also heard this otc can cause problems. Any comments.

 

Tyrosine and Tyramine Different

Posted by linkadge on October 13, 2002, at 18:30:10

In reply to Re: New to MAOIs, posted by cybercafe on October 13, 2002, at 11:46:34

Tyrosine is an amino acid precursor to
Dopamine and norepinephrine (indirectly).
From what I've heard, it can help in some
cases in combo with certain drugs, but
its not very relyable. Personally I would
add Folic acid and Vitamin B12, to try and
boost an MAOI's effectivness.


Tyramine is a food substance that
is metabolised my MAO.


Linkadge

 

Vitamin B6 and Nardil Bobbiedobbs

Posted by katie tkm on October 13, 2002, at 22:34:33

In reply to Re: side effects of MAOI's, posted by Bobbiedobbs on October 4, 2002, at 0:30:34

dear phil,

thanks for telling me about your experiences. it was good to know.

i think the nardil is really working for me - i just can't help wondering if parnate might have less side effects. i guess i can't exactly predict my response from other people's side effects because we/they're all so different.

i'm on week 6 and hanging in there with fatigue, constipation,insomnia and sexual disturbances. it's not too bad. so many other side effects have faded i hope that these will go too - and not in 4 months as some articles suggest!

i've read about taking vitamin B6 with nardil because it can cause a depletion. SOMEWHERE i read that it might be a good idea to separate the B6 and nardil dose to increase the vitamin absorption (because nardil blocks B6 absorption mostly at the same time when it is being absorbed??). like so many of the snippets i remember from hours of reading on the net i can't find the info again!!!

do you know anything about this separating when you take B6 and nardil issue?

anyway i hope you are doing ok.
best wishes
katie

 

Success with Marplan? cybercafe

Posted by ZeeZee on October 14, 2002, at 9:42:35

In reply to Re: New to MAOIs, posted by cybercafe on October 13, 2002, at 11:46:34

Has anyone used with success Marplan? If so, how do the side effects differ from Nardil and Parnate? Was it as effective? I used Nardil in the past, switched to Parnate because of s/e and it was very helpful. Recently re-tried Parnate but couldn't handle some very weird s/e that I never had before. Am considering trying a MAOI again, since they've been the only AD to work and not increase my problem with anxiety/panic. Any experiences with Marplan would be appreciated.
Thanks,
Lisa


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