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Dr. Bob is Robert Hsiung, MD,
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Posted by Dave1 on May 10, 2002, at 19:13:24
HI
Does anyone know or had success with celexa for OCD? Or maybe in combo with another drug. I thought I read something about it but am not sure now.
Thanks,
DAVE
Posted by MomO3 on May 11, 2002, at 0:20:48
In reply to celexa and OCD, posted by Dave1 on May 10, 2002, at 19:13:24
> HI
>
> Does anyone know or had success with celexa for OCD? Or maybe in combo with another drug. I thought I read something about it but am not sure now.
>
> Thanks,
> DAVE
I had an interesting experience with Celexa. I took Paxil(which is supposed to help OCD) for 2 weeks I was virtually unable to put one foot in front of the other, I couldn't *remember* how to clean my kitchen - I would wander in my kitchen for hours trying to clean it and it would still be a mess. Then I switched to Celexa - it cleared my thinking immensely, everything snapped back into focus, but so did all of the little OCD annoyances. Personally, I would say that it exacerbated my OCD. My first week on Celexa I reorganized every closet in my house...you know that wiping the dust off of the floorboards in the closet type of thing. I was actually hoping that effect would last a little longer so I could get the rest of my house (& floorboards) clean, but it didn't.I haven't ever read exactly what Celexa is supposed to treat, but I stopped taking it because it wasn't helping with my anxiety.
Good luck!
Holly
Posted by rainbowlight on May 11, 2002, at 0:35:21
In reply to celexa and OCD, posted by Dave1 on May 10, 2002, at 19:13:24
I took Celexa also. It made me a raving clean freak, which is the OCD problem I had in the first place. It is very activating and gives you tons of energy, which might be a good thing or a bad thing depending on what type of OCD you have.
Posted by Dave1 on May 12, 2002, at 17:33:58
In reply to Re: celexa and OCD, posted by rainbowlight on May 11, 2002, at 0:35:21
HI,
Thanks for your responses. Here's my situation. I'm currently taking clomipramine for depression and OCD. I have augmented it with lithium and risperidal. The lithium augmentation helped the depression temporarily but neither lithium or risperidal helped the OCD.
I think I might try augmenting with citalopram (celexa I think). I found an article on PUBMED indicating this combo. might work. I'll show the article at the end of the post.Bye,
Dave
Citalopram for treatment-resistant obsessive-compulsive disorder.
Pallanti S, Quercioli L, Paiva RS, Koran LM.
Istituto di Neuroscienze and University of Florence Medical School, Florence, Italy.
We investigated the comparative efficacy of citalopram vs. citalopram administered with clomipramine, in treatment-resistant obsessive-compulsive disorder (OCD). Sixteen adult outpatients participated in a 90-day, randomized, open-label trial. Eligible patients were aged 18 to 45 years, had moderate to severe DSM-III-R OCD of >/= one year's duration, a baseline Yale-Brown scale (Y-BOCS) score of >/= 25 and no other active axis I diagnosis, and had failed adequate clomipramine and fluoxetine trials. The citalopram-plus-clomipramine group (n = 9) experienced a significantly larger percent decrease in mean Y-BOCS score by day 90 than the citalopram alone group (n = 7). Only one citalopram patient decreased her score by >/= 35%, and two by >/= 25%. All nine citalopram-plus-clomipramine patients experienced decreases of 35%. Side effects were mild to moderate in both groups. We also treated with citalopram six OCD patients who had not tolerated fluoxetine alone and clomipramine alone; three achieved Y-BOCS score decreases of >/= 35% at 90 days. Since citalopram does not significantly affect clomipramine metabolism, the improvement in the combined drug group is unlikely to have resulted from increased plasma clomipramine levels. Double-blind controlled trials are needed of citalopram in OCD, and of combining citalopram with clomipramine in treatment-resistant OCD.
Posted by Dave1 on May 13, 2002, at 18:29:54
In reply to Re: celexa and OCD, posted by MomO3 on May 11, 2002, at 0:20:48
HI AGAIN,
Holly mentioned that Celexa cleared up her confusion. Did it make you less confused than you are normally. I get memory loss and confusion from my depression. If Celexa would help with that I would be more relaxed.
Dave
> > HI
> >
> > Does anyone know or had success with celexa for OCD? Or maybe in combo with another drug. I thought I read something about it but am not sure now.
> >
> > Thanks,
> > DAVE
>
>
> I had an interesting experience with Celexa. I took Paxil(which is supposed to help OCD) for 2 weeks I was virtually unable to put one foot in front of the other, I couldn't *remember* how to clean my kitchen - I would wander in my kitchen for hours trying to clean it and it would still be a mess. Then I switched to Celexa - it cleared my thinking immensely, everything snapped back into focus, but so did all of the little OCD annoyances. Personally, I would say that it exacerbated my OCD. My first week on Celexa I reorganized every closet in my house...you know that wiping the dust off of the floorboards in the closet type of thing. I was actually hoping that effect would last a little longer so I could get the rest of my house (& floorboards) clean, but it didn't.
>
> I haven't ever read exactly what Celexa is supposed to treat, but I stopped taking it because it wasn't helping with my anxiety.
>
> Good luck!
> Holly
Posted by Dave1 on May 14, 2002, at 8:58:28
In reply to celexa and OCD, posted by Dave1 on May 10, 2002, at 19:13:24
HI AGAIN,
Sorry to keep bothering you two, I wasn't sure if you saw my other post.
Holly mentioned that Celexa cleared up her confusion. Did it make you less confused than you are normally. I get memory loss and confusion from my depression. Do you think celexa would clear that up?
Thanks alot,
Dave
Posted by JaneB on May 14, 2002, at 11:57:04
In reply to Re: To Mom and Rainbowlight, posted by Dave1 on May 14, 2002, at 8:58:28
> HI AGAIN,
>
> Sorry to keep bothering you two, I wasn't sure if you saw my other post.
>
> Holly mentioned that Celexa cleared up her confusion. Did it make you less confused than you are normally. I get memory loss and confusion from my depression. Do you think celexa would clear that up?
>
> Thanks alot,
>
> DaveI can tell you that Celexa definitely helped my memory loss and confusion. It is not great but a lot better than when very depressed. I can function and teach and read again. There is hope with Celexa.
JaneB
This is the end of the thread.
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