Psycho-Babble Medication Thread 86771

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High-Dose Parnate

Posted by christophrejmc on December 13, 2001, at 0:36:22

Has anyone tried high-dose Parnate (tranylcypromine) (above, say, 90mg)? If so, how did it compare to lower dosages? Also, were there any complications (e.g. hypertensive crises)? There was some mention here a while ago that high dosages of Parnate might have actions not seen at low dosages. Thanks for any input.

Christophre.

 

Re: High-Dose Parnate christophrejmc

Posted by Elizabeth on December 13, 2001, at 15:55:34

In reply to High-Dose Parnate, posted by christophrejmc on December 13, 2001, at 0:36:22

> Has anyone tried high-dose Parnate (tranylcypromine) (above, say, 90mg)?

I know it's been used at doses much higher (into the high 100's), and there are at least a few people here who've tried it. I wasn't able to do that because Parnate makes my blood pressure shoot up (when I was taking it, I had to limit each dose to 10 mg -- for quite a while I was taking 10 mg six times a day). I have thought about asking to try it with an antihypertensive drug (an ACE inhibitor, I suppose, would be the best choice -- I did talk to my pdoc about doing this at one point, when I was living in Cambridge).

So the only advice I can give you if you're going to try this is to monitor your blood pressure. (But don't let it turn into an obsession, eh? :-) )

-elizabeth

 

Re: High-Dose Parnate Elizabeth

Posted by christophrejmc on December 13, 2001, at 19:31:39

In reply to Re: High-Dose Parnate christophrejmc, posted by Elizabeth on December 13, 2001, at 15:55:34

> I wasn't able to do that because Parnate makes my blood pressure shoot up (when I was taking it, I had to limit each dose to 10 mg -- for quite a while I was taking 10 mg six times a day).

My bp got up to 160/90 the first time I took two 10mg's, but I haven't had this problem since. I'm a little worried about higher dosages, but I think I'll need to divide the doses anyway to counteract the fatigue.

As for the blood pressure obsession, I think it's too late -- bplog.txt is getting quite large ;).

Christophre.


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