Psycho-Babble Medication Thread 67742

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Re: Hypertensive crises, update

Posted by Lorraine on September 4, 2001, at 21:25:50

In reply to Re: Update Lorainne, Elizabeth, et. al. » shelliR, posted by Lorraine on September 3, 2001, at 21:45:26

Doing my washout from Parnate to Nardil with adderal and neurontin. Took 10 mg adderal this morning, fine. Took second 10 mg adderal this afternoon, started feeling funny. Tingling moving up my neck to my head and headache coming on, waited a little (not long) felt worse. Took blood pressure 165/97, i think. Took antidote crushed it under tongue, blood pressure came down, right away and within an hour or so was clearly normal, although high for me on MAO. I feel very hungover. Not an experience I want to repeat necessarily.

 

Re: Update Lorainne, Elizabeth, et. al. » Lorraine

Posted by shelliR on September 5, 2001, at 11:15:08

In reply to Re: Update Lorainne, Elizabeth, et. al. » shelliR, posted by Lorraine on September 3, 2001, at 21:45:26

Hi Lorraine.

> What, both of us gone the same time. Well, I'm home now (big sigh).

big sigh of relief? I don't know if long weekends fit under the heading of vacations.

re continuing wellbutrin:
> > I'll be in a very mellow, non-pressured familar place, mostly by myself. So I am going to try to go up to 300mg. If that does nothing for the depression, I'm ready to move on.
> It's nice to try this is a non-pressured environment where you can watch your reactions, although I find that sometimes I can miss seeing my depression if I am not around people.

My primary depression is there, whether people are around or not. That's why I call it so physical. I have had two days of 300mg of wellbutrin with very little improvement. It is so much easier to tolerate being depressed when I don't have to work--at least this type of depression.

But then I have also another type of depression/anxiety/angst that has to do with people and fitting in in life and that is much more apparent when I am around people, especially new people or people I don't know well. I'm not sure whether that could be medicated and if so, I'm not sure what I would have to give up in exchange.
In the last few days small things have made me realize that I have both very strong right and left brain hemispheres. But I can only be in one side or the other; my transitions are incredibly slow. Anyway I am really excited about realizing that. Maybe a small corpus colluseum (sp?). So maybe if my neurotic existential depression/anxiety was medicated, I would also lose my excitement at these useless discoveries.

An example: For months I've been using :-) because I know it is the sign for smile. But I was thinking okay, first colon, then dash then parenthesis. For the first time last month I SAW that OF COURSE it is a smile sideways. I felt so stupid, because I am so visual. Then some other similar things came to mind and I realized when I am in left brain mode (i.e., writing posts, I am totally out of visual mode), so that was really fun to realize and I felt less stupid.

Anyway, I can only write things like that on the board because the post is directed to you. If it was directed to the whole board, I'd feel that I was totally boring everyone.

I'll take my chances on boring you < g >.

> > > > [re oxy]Like I took doseII at 3pm and 5mg of valium, and I am very tired, but feeling good.
> You don't mind feeling very tired? that would drive me nuts. I hate sedation.

Well I have always been a spurt person--put total energy out then become really tired later. And I do felt strange about being so tired in the afternoon (sort of ashamed), and sometimes when I'm not home, it felt really bad. But that was a side effect that I *was* willing to accept. And if I can sleep for even 20 minutes to half-hour in the afternoon, I am totally energized the whole evening. I think not having children made it easier for me and working for myself. Still, it's amazing to have all this energy on wellbutrin, and if it doesn't work as my main AD, I can see it as an adjunct (rather than stimulants, for example)

BTW, I have asked my pdoc to do a nardil/wellbutrin combo, but he was less than enthusiastic. He said he has another idea first (which of course he didn't share with me). I think with him if I really insist on trying something, he will prescribe it for me. But since the oxycontin is making life even more than bearable (when I am up to the right amount), I will try to be patient with his ideas.


> Shelli, you are very strong period. I don't worry about whether you would feel pressure to conform to my opinion

That's good. I do have certain vulnerabilies that make me feel not very strong. And don't say (please) that everyone does--because not everyone wants to die because of their vulnerabilities.

> or even elizabeth's.
*even* Elizabeth's < g >. I get different things from both of you.


> Have you explained to him that you want to move up on your doses more gradually?

He is not ideal in the area of accepting explanations. He says, "take as much oxy as you need, don't worry". That's his most often response to me: "don't worry" It's definitely a dismissal as well as reassurance. But let's not go there. :-)

> I would worry about the drug interactions and beyond that I might try it. (Dr. Koop has a good interaction checker).

I've already combined oxy and vicodin a couple of times for bad migraines.
> I've never kept anything from my pdocs before, but I feel like it's my body and I'm the one at risk if he's going to set a limit on the oxy.
> I don't think he is going to set a limit really. so perhaps honesty should rule the day. I haven't kept anything from my pdoc. I sort of figure that he is willing to take fairly substantial risks with me and I owe him honesty. I am also pretty confident that once you breach the "trust", all that risk taking gets withdrawn. More important for me to maintain the relationship than mess we my meds in a way he would be uncomfortable with.

My goal is to enhance his comfort level.
??????? *his*? I think maybe I read that out of context.

Whew! Having said all that, I don't think you should add the vicoden without his knowledge and consent:-(
>
I think I just caught your thought process in real time. < g >. I think you're right. I didn't feel at all guilty not telling him about the mixing for migraines because it might have become too complicated and I've only done it twice. But in general trust is incredibly important


> > > >And also he thinks it wastes time, because he knows where we're going.
> This would definately bother me, but then I like to have a lot more control and understanding about my medical stuff than most doctors are willing to indulge.

Well, of course this is not a perfect match. But we've been there before. :-)
>

> > Details, please. dress, body type, age, etc.
> Tall, sixty-something, lean, stooped, wirey hair. Passionate about his craft, tendency to think aloud, always willing to think and give full weight to what you say unless it is in accordance with orthodox medicine:-)

Passionate is good. And he listens and thinks too. Sounds good; can't remember what that feels like. I wonder why he (and some people in general) are stooped.
>
>
>
> > > > OK,OK,OK. See I thought the term pills included both tablets:
> > good point.
> Yeah, but I was still able to drive you nuts with it< vbg >

Oh, my, did it show? < vbg >

> Update on parnate, please.
> Temper and irritation became a fairly major issue so I scales back from 15mg to 12.5 with the end result being that I lacked mood support and was irritable to boot. So I think I'm on to Nardil. By the way, did you say you tried Nardil augmented with Desipramine? In the archives, someone raved about this combo.

Does Desipramine have a brand name? I can't recall what that is off the top of my head.

I have a feeling that you will not be as sensitive to nardil as you were to parnate. Aside from sleep disturbance and afternoon fatigue (which I think is partially just my own blood sugar patterns), I was not at all conscious of taking a drug.

I wouldn't be disappointed if the nardil didn't kick in as quickly as parnate. I've never read about immediate anti-depressant with nardil. (Hopefully YMMV) If you get the afternoon fatigue or have difficulty sleeping, I'm sure you can work on that after. As for sleeping at night, I do need something to stay asleep. That has been a small price to pay considering that I feel that nardil really saved my life.

Be patient if my responses are not immediate. It turns out that by the time it's 10pm, I'm totally exhausted (no naps, so far). It takes more energy for me to write because I'm not used to using a laptop.

shelli

 

Re: Update Lorainne, Elizabeth, et. al. » shelliR

Posted by Lorraine on September 6, 2001, at 10:29:25

In reply to Re: Update Lorainne, Elizabeth, et. al. » Lorraine, posted by shelliR on September 5, 2001, at 11:15:08

Shelli:
>
> > What, both of us gone the same time. Well, I'm home now (big sigh).
>
> big sigh of relief?

Yes, still happy to be home, although I do love the place I was visiting-- a friends house that was homesteaded during the California land rush. No running water, 1300 acres in the middle of nowhere. It was beautiful and he is a good friend.

> re continuing wellbutrin:
> > > My primary depression is there, whether people are around or not. That's why I call it so physical. I have had two days of 300mg of wellbutrin with very little improvement. It is so much easier to tolerate being depressed when I don't have to work--at least this type of depression.

Sorry the Wellbutrin isn't kicking in grand force for you. For me being enervated is a large part of my depression so if I am on an activating drug and "get busy" things seem ok. Then if I slow down and talk with people, it is very obvious that I am still in my depression. I guess I try to distract myself a lot.


> > > But then I have also another type of depression/anxiety/angst that has to do with people and fitting in in life and that is much more apparent when I am around people, especially new people or people I don't know well. I'm not sure whether that could be medicated and if so, I'm not sure what I would have to give up in exchange.

Sounds like a bit of Social Anxiety? I know I have some.


> In the last few days small things have made me realize that I have both very strong right and left brain hemispheres.

What an interesting thing to notice. Then your transition into the artist mode is a transition from one hemisphere to another.


>

> > >Still, it's amazing to have all this energy on wellbutrin, and if it doesn't work as my main AD, I can see it as an adjunct (rather than stimulants, for example).

I found Moclobemide very activating as well. I only had to leave it because of the anxiety it caused me--which was not as bad as Wellbutrin, but too much for me.


> > > BTW, I have asked my pdoc to do a nardil/wellbutrin combo, but he was less than enthusiastic. He said he has another idea first (which of course he didn't share with me).

Sounds like he has some plan mapped out in his head for your course of treatment. Maybe he derives cues from your reactions to the various drugs he tries you on.

> > >I do have certain vulnerabilies that make me feel not very strong. And don't say (please) that everyone does--because not everyone wants to die because of their vulnerabilities.

Your vulnerabilities sound very tender, more like wounds? Is there shame attached?

> > >He says, "take as much oxy as you need, don't worry". That's his most often response to me: "don't worry" It's definitely a dismissal as well as reassurance. But let's not go there. :-)

He's in the driver's seat as long as he knows where he is going and you are enjoying the view so to speak....



> > >[re trust and pdoc] My goal is to enhance his comfort level.
> ??????? *his*? I think maybe I read that out of context.

You said you got this further on in your post. But just to make clear, I see the relationship with pdocs as a two way street. They have a certain amount of liability exposure for making more aggressive drug choices and need some assurance that we can be trusted to handle those drugs or they will become more conservative--which, when you are treatment resistant is not helpful. So I work on his comfort level. I'm a good girl; I report back; I don't throw him any loops and in turn, he is willing to try what he thinks will really work for me and not worry about liability issue. Now my therapist, on the other hand, works on my comfort level;-)---see the wink?

> > > > >And also he thinks it wastes time, because he knows where we're going.
> > This would definately bother me, but then I like to have a lot more control and understanding about my medical stuff than most doctors are willing to indulge.
>
> Well, of course this is not a perfect match. But we've been there before. :-)

Shelli, I just have an incredible distrust of doctors and their abilities. I know it's unfair, but there it is. I'm sure my heavy handed participation in the drug selection for me is no better than your pdocs informed plan. At worst, we are both random and if that's the case, then it doesn't matter whose plan you follow so long as you don't unnecessarily retrace your steps.


>
> > >Passionate is good. And he listens and thinks too. Sounds good; can't remember what that feels like. I wonder why he (and some people in general) are stooped.

He is stooped because of mild scholiosis (sp?)--curvature of the spine.

I'm off Parnate now. First day I tried using adderal during my washout period and had a mild hypertensive crises. I say mild to appease the medical gods because my blood pressure (165/96?) didn't approach a medical emergency. To me though the crises was extreme--very bad headache and terrible stiff neck. I took the antidote, relatively early (within 15 or 20 minutes of onset--hey, it was my first time, I wasn't sure what was going on). That really wiped me out. I'd say I was down for the count for 2 days. Yesterday, was filled with severe hot flash types
of symptoms and I don't know if this was from withdrawal from Parnate, the hypertensive crises, or the fact that I went of estrogen about 4 weeks ago. Plus, now that I am off the Parnate, I think it was causing some sexual dysfunction.

I start the Nardil on Saturday. The sleep disruption thing is very upsetting to me and I'm not sure how I will fair with that side effect. Last night I took a valium in addition to the ambien and neurontin and slept well. But I'm not sure I want a benzo habit.


> > > I have a feeling that you will not be as sensitive to nardil as you were to parnate. Aside from sleep disturbance and afternoon fatigue (which I think is partially just my own blood sugar patterns), I was not at all conscious of taking a drug.

I hope you are right. The afternoon fatigue though seems common and I don't think it's your blood sugar pattern. I started another thread on it and from the responses I got (n=3) it seems that blood pressure reaches a natural low between 3 and 4 pm daily; one person was medicated for low blood pressure while on MAOs; another adjusted over time (but didn't take his blood pressure.) My hunch is it's blood pressure related and because I took mine during on of these slumps and it was so clearly low my plan is to use salt tablets (there is a buffered type that is recommended--Thermosomething) and drink plenty of water and see if that helps. It will be my little experiment, I'll let you know.


> > >I wouldn't be disappointed if the nardil didn't kick in as quickly as parnate. I've never read about immediate anti-depressant with nardil.

Unfortunately, I think you are right

[re desipramine and nardil]: Desipramine is the TCA that elizabeth is one right now and I believe that desipramine is it's brand name. If you do go back to Nardil, this combo might be worth a shot. Desipramine has a reputation for being activating, but, according to elizabeth, is better for sleep cycles than MAOs.

How is your vacation treating you otherwise?

Lorraine

 

Re: Update Lorainne, Elizabeth, et. al. » Lorraine

Posted by shelliR on September 6, 2001, at 13:34:24

In reply to Re: Update Lorainne, Elizabeth, et. al. » shelliR, posted by Lorraine on September 6, 2001, at 10:29:25

Hi Lorraine.

re continuing wellbutrin:
>Sorry the Wellbutrin isn't kicking in grand force for you. For me being ener is a large part of my depression so if I am on an activating drug and "get busy" things seem ok. Then if I slow down and talk with people, it is very obvious that I am still in my depression. I guess I try to distract myself a lot.

In some ways being energized is helpful when I'm depressed. At other times, when I hurt so badly I can't stand it, sleep has always been my only escape from the pain. And that is not an option on wellbutrin (for better and worse).

> > > > But then I have also another type of depression/anxiety/angst that has to do with people and fitting in in life and that is much more apparent when I am around people, especially new people or people I don't know well. I'm not sure whether that could be medicated and if so, I'm not sure what I would have to give up in exchange.
> Sounds like a bit of Social Anxiety? I know I have some.

I don't know if it's social anxiety, per say. I've never thought of it that way, but maybe it is a specific type. I talk very easily with people and generally have the feeling that I am interesting and entertaining. I am very light in the company of others, which is probably something that would surprise you--considering the intensity of my posts.

Most of my anxiety re people is how to navigate through life solo. My closest friend (male) remarried two years ago and so my immediate world has changed.

On this vacation I am fine by myself--have this really cute little house and cable to watch the US open, plus short rides bring me into incredible natural beauty and awesome art. But when I am around couples vacationing together, I get very anxious about myself and go back to my little house.

> > > > BTW, I have asked my pdoc to do a nardil/wellbutrin combo, but he was less than enthusiastic. He said he has another idea first (which of course he didn't share with me).
> Sounds like he has some plan mapped out in his head for your course of treatment. Maybe he derives cues from your reactions to the various drugs he tries you on.

I think he only pretends he has a plan. And depending on what he wants to do next, I may really push the nardil/wellbutrin combo, although the nardil was totally not working any more for me.
>

> He's in the driver's seat as long as he knows where he is going and you are enjoying the view so to speak....

No, I don't see it that way. I see us sharing the driver's seat. (He probably sees me as a backseat driver. < g >) I wanted to try Parnate; he wasn't enthusiastic but wrote the prescription. I had wanted to try wellbutrin before, he thought it was too complicated as a base drug, but when I wanted to go back on nardil, he brought up trying wellbutrin as *his* idea. It's much more of a personality thing--like he has to feel like he's in control, than it is really a control thing. At least so far. I would not take a drug I'm not comfortable with and it remains to be seen if he is willing to be a little bit risky with nardil and wellbutrin. (He doesn't like to work with MAOIs). But I am curious about his next idea. It was his idea to go to oxy, which I think was the right thing to do in terms of less ups and downs than vicidin. I actually don't believe he even had his next idea yet when he said that.

> I'm off Parnate now. First day I tried using adderal during my washout period and had a mild hypertensive crises. I say mild to appease the medical gods because my blood pressure (165/96?) didn't approach a medical emergency. To me though the crises was extreme--very bad headache and terrible stiff neck. I took the antidote, relatively early (within 15 or 20 minutes of onset--hey, it was my first time, I wasn't sure what was going on). That really wiped me out.

Yes, I had the same thing happen with adrafinil and nardil, and didn't have a antidote. I drove quickly to the pharmacy to take my BP, which also was up to 165 or so. I can't believe in retrospect I didn't drive to the hospital. But I had been taking nardil for so long without any hypertensive reactions that I didn't even own a cuff. But it didn't affect me at all after the incident. I did buy a cuff, though.

I'd say I was down for the count for 2 days. Yesterday, was filled with severe hot flash types
> of symptoms and I don't know if this was from withdrawal from Parnate, the hypertensive crises, or the fact that I went of estrogen about 4 weeks ago.

probably not worth it to even try to figure that one out

Plus, now that I am off the Parnate, I think it was causing some sexual dysfunction.

I don't think I had any sexual dysfunction on nardil, but it's really hard to tell if it had a small effect because I was on it almost my entire adult life. Opiates make me feel very sensual, but they definitely interfere with full orgasmic release.

> I start the Nardil on Saturday. The sleep disruption thing is very upsetting to me and I'm not sure how I will fair with that side effect. Last night I took a valium in addition to the ambien and neurontin and slept well. But I'm not sure I want a benzo habit.
>
See, I don't get that kind of thinking. I see it as you go around once and then it's over. (as far as I know, yet) So life should be as positive as possible. If a benzo at night keeps you on an antidepressant that works, it sort of strikes me as puritanical to worry about a "habit".


> > > >I wouldn't be disappointed if the nardil didn't kick in as quickly as parnate. I've never read about immediate anti-depressant with nardil.
>
> Unfortunately, I think you are right
>
> [re desipramine and nardil]: Desipramine is the TCA that elizabeth is one right now and I believe that desipramine is it's brand name.

Oh yea, it looked familiar. I tried TCAs in my early twenties and they totally spaced me out. I'd be afraid to try again I think. I never got past one day on them, but I'm not sure which TCAs I tried; it was so long ago.
>
re nardil: I don't think I got the sleeping side effect until it kicked it for me.

BTW, still no wellbutrin AD effect--today my fourth day on 300mg. No side effects, either now. But I did get some encouragement on the board, and it did take forever for nardil, so the trial goes on, at least until I see my pdoc on Monday.
>
Shelli

 

Re: Update Lorainne, Elizabeth, et. al. » shelliR

Posted by Lorraine on September 7, 2001, at 9:23:57

In reply to Re: Update Lorainne, Elizabeth, et. al. » Lorraine, posted by shelliR on September 6, 2001, at 13:34:24

Hi Shelli:


> In some ways being energized is helpful when I'm depressed. At other times, when I hurt so badly I can't stand it, sleep has always been my only escape from the pain. And that is not an option on wellbutrin (for better and worse).

Sounds like hypersomnia (my personal favorite when meds don't prevent it), which also falls in the category of atypical depression.

> > >I am very light in the company of others, which is probably something that would surprise you--considering the intensity of my posts.

Wouldn't really surprise me. I think you're funny.

> > > Most of my anxiety re people is how to navigate through life solo. My closest friend (male) remarried two years ago and so my immediate world has changed.

This would be very hard for me. As hard as it is to go on vacation with my family which wants to "do" something all the time. This would be harder. It would be good for you to find another single close friend to do things with---support groups? Not for abuse survivors (I think you said you were tired of those), but maybe just a NDMDA group?

>
> On this vacation I am fine by myself--have this really cute little house and cable to watch the US open

We've been watching it too.

> > >, plus short rides bring me into incredible natural beauty and awesome art. But when I am around couples vacationing together, I get very anxious about myself and go back to my little house.

We give up so much for this illness, it seems. Day to day we don't have to notice, but then we do something and the loss is so stark.


> > > I think he only pretends he has a plan. And depending on what he wants to do next,

That may be as good as "having" a plan. It maintains forward momentum.

> > >(He probably sees me as a backseat driver. < g >) I wanted to try Parnate; he wasn't enthusiastic but wrote the prescription.

Back seat drivers are good for control freaks--they drive them nuts:-)

> > > Yes, I had the same thing happen with adrafinil and nardil, and didn't have a antidote. I drove quickly to the pharmacy to take my BP, which also was up to 165 or so. I can't believe in retrospect I didn't drive to the hospital.

Didn't go to the hospital or take an antidote???? What happened? did you pressure come down on its own?


> > > I start the Nardil on Saturday. The sleep disruption thing is very upsetting to me and I'm not sure how I will fair with that side effect. Last night I took a valium in addition to the ambien and neurontin and slept well. But I'm not sure I want a benzo habit.
> >
> See, I don't get that kind of thinking. I see it as you go around once and then it's over. (as far as I know, yet) So life should be as positive as possible. If a benzo at night keeps you on an antidepressant that works, it sort of strikes me as puritanical to worry about a "habit".

You are making me think:-) I think you are probably right, it is some puritanical nonsense loop that I run through my head. I probably need to get over it now. I've been taking valium and ambien to sleep the last couple of nights. Partly because I still have a bad neck aches from the hypertensive crises. I have slept well.

> >BTW, still no wellbutrin AD effect--today my fourth day on 300mg. No side effects, either now. But I did get some encouragement on the board, and it did take forever for nardil, so the trial goes on, at least until I see my pdoc on Monday.

I'll be anxious to see what he says and what his plan is :-)

Lorraine

 

Re: elizabeth, come back we miss you Elizabeth

Posted by Lorraine on September 7, 2001, at 10:14:23

In reply to Re: Parnate stuff » Elizabeth, posted by Lorraine on September 3, 2001, at 20:48:59

elizabeth: You didn't respond to my 9/3 message and i miss you.:-)

> Elizabeth:
>
> I was gone for the long weekend up near the Russion River in Northern California and so my delay in responding.
>
> [re Parnate]
> > > > > It's been about a month, although I increase my dosage about 2 weeks ago to 15 mg.
>
> > Okay...I wouldn't base your conclusions as to how well it will work on how well it's working at 15 mg. (The minimum effective dose is usually 30, although I think that some effects become noticeable at 20.)
>
> I won't make it to 20, I don't think. When I went to 15, I started becoming irritable and cranky. I had hoped this would abate with time, but it didn't, so I stepped back down to 12.5, which left me with insufficient mood support and irritable to boot. So, I think, I'm off the Parnate and on to Nardil after a 5 day washout period on amphetamines and neurontin.
>
> [re Ambien] Is this a strange medication or what????!! I'm not sure I get it yet. I take the pill 10 mg and take 800 neurontin (actually chewing them slightly so that the caps will process quicker), then wait 30 minutes, then lay down and feel like there is no way I can sleep. Maybe 30 minutes pass, then I start counting my breaths (which is what I do to still my mind) and tell myself I only have to count 20 breaths (breath in 1, 2; breath out 1,2,3,4). By breath 10 or so I'm asleep, but I don't know what to attribute it to. I never feel like I am coming on to the Ambien. Does this sound right?
>
>
> > I don't know about Neurontin; I never had that problem with Ambien.
>
> I'm glad to hear that the Ambien is neither addictive nor habituating. I went out and bought ear plugs to help with the sleeping also.
>
> So you are going to try augmenting your Desipramine with stimulants, I read. Adderal worked well with me. I read in the archives of Psychobabble that Desipramine and Nardil are a good combination--that the Desipramine avoided the weight gain issues with Nardil.
>
> How are your driving lessons going? I tried to buy the book you recommended, but it's out of print so I've requested notification from Amazon of used copy sales (here's your chance!< g >)

 

Re: Compounding pharmacy options » shelliR

Posted by Lorraine on September 7, 2001, at 15:30:10

In reply to Re: Update Lorainne, Elizabeth, et. al. » Lorraine, posted by shelliR on September 6, 2001, at 13:34:24

Shelli:

I was thinking about the post by Zo on August 21 re "Buprenorphine--just started trial-Elizabeth" and thought of you and your quandry about oxy and dosing. Isn't one way to get around your dosing problem to have your oxy ground and compounded by a compounding pharmacy into smaller doses? This could be in pill or lotion form. My pdoc had mentioned to me that one of his patients was having a lot of side effects and was allergic to certain meds and that they started compounding them into lotions that she applies on her skin, which seemed to help. Anyway just a thought.

 

Re: Update Lorainne, Elizabeth, et. al. » Lorraine

Posted by shelliR on September 7, 2001, at 22:08:05

In reply to Re: Update Lorainne, Elizabeth, et. al. » shelliR, posted by Lorraine on September 7, 2001, at 9:23:57

Hi Lorraine


re: oversleeping
> Sounds like hypersomnia (my personal favorite when meds don't prevent it), which also falls in the category of atypical depression.

well, don't most people who are depressed (and not simultaneously hyper) want to get in bed and pull the covers over their head when they are depressed?
Is this only part of atypical depression? I suppose that type A depressives might decide that a good long walk might help? Or immersing themselves in their work. Most workaholics though, are not depressives; they are people who are at their best in that arena.


> > > >I am very light in the company of others, which is probably something that would surprise you--considering the intensity of my posts.
> Wouldn't really surprise me. I think you're funny.

I'm much more entertaining in person. :-)

> > > > Most of my anxiety re people is how to navigate through life solo. My closest friend (male) remarried two years ago and so my immediate world has changed.

> This would be very hard for me. As hard as it is to go on vacation with my family which wants to "do" something all the time. This would be harder. It would be good for you to find another single close friend to do things with---support groups? Not for abuse survivors (I think you said you were tired of those), but maybe just a NDMDA group?

maybe. there's lots of things to do to meet people; I'm probably support grouped out. I can't imagine going on a vacation with a friend--too intense, although it would make me feel less vulnerable. All my friends at the moment are married. I keep planning on going to a function of the vegetarian association where I live, but I always find some excuse not to go. Not out of fear, more out of laziness. Food is not a stimulating subject for me, but there might be interesting people. I entertain myself very well, so I don't have a lot of incentive. I did try going to a movie club--movie, then discussion, but I got really bored listening to people analyze the movie. The people I listen to on NPR are a lot smarter and more interesting, and I don't have to get out of my car. (Bad attitude.)

One of my married friends has nothing in common with her husband; it's a very strange relationship (with no children, nor any planned). She is usually up to coming along, if I want to do something that I don't feel comfortable doing alone, like going to a concert. And I do that for her, also.

>
> > > > Yes, I had the same thing happen with adrafinil and nardil, and didn't have a antidote. I drove quickly to the pharmacy to take my BP, which also was up to 165 or so. I can't believe in retrospect I didn't drive to the hospital.
> Didn't go to the hospital or take an antidote???? What happened? did you pressure come down on its own?

Yes, I keep taking my BP and it never got to 170. Within about fifteen minutes it was back down to normal. This happened twice; the first time I was pretty scared but figured they'd call an ambulance for me if necessary. When I was on parnate I was better prepared (with cuff). None of my pdocs have recommended keeping an antidote with me. If I go back on nardil (especially with wellbutrin), I'll be better prepared.
>

>
> You are making me think:-)
Well thinking is good, right? :-)

> I'll be anxious to see what he says and what his plan is :-)

As long as the oxy is working , I am really not feeling depressed. I would like to increase the wellbutrin again. I'd do it tommrrow, but I don't want take any chance in messing up my last day here. I've put in a lot of time with the wellbutrin with no anti-depressant effects (I can tell because I wake still up still in a very bad depression until the morning oxy kicks in), but as long as I've hung in this long--I'd like to see what happens in another ten days or so, working up to 450mg.

It is really nice to take such a complete break from work. I could extend this vacation if I didn't have work obligations and if the U.S. open continued. It's sort of centering me, and my friend and I are e-mailing back and forth about it. (We are both tennis obsessed; that's how we got to be such good friends. He still plays; and I watch the matches on tv)

Good luck tomorrow with nardil.

Shelli

 

Re: Compounding pharmacy options » Lorraine

Posted by shelliR on September 7, 2001, at 23:16:49

In reply to Re: Compounding pharmacy options » shelliR, posted by Lorraine on September 7, 2001, at 15:30:10

> Shelli:
>
> I was thinking about the post by Zo on August 21 re "Buprenorphine--just started trial-Elizabeth" and thought of you and your quandry about oxy and dosing. Isn't one way to get around your dosing problem to have your oxy ground and compounded by a compounding pharmacy into smaller doses? This could be in pill or lotion form. My pdoc had mentioned to me that one of his patients was having a lot of side effects and was allergic to certain meds and that they started compounding them into lotions that she applies on her skin, which seemed to help. Anyway just a thought.

Actually that might have been a good idea for my first increase. At this point I realize that I probably need to go up a full dose to feel the anti-depressant effects. I am taking my old doses, and strattling an extra one in the middle, to keep the dose down somewhat. But if I am suffering too much I will take my own advice to you, re going around once. :-) Unlike opiates, however; in my experience, I have never had to raise my dose of benzos for sleep.

You should have thought of this earlier. < g >

Shelli

 

Re: Update Lorainne, Elizabeth, et. al. » shelliR

Posted by Lorraine on September 8, 2001, at 12:53:48

In reply to Re: Update Lorainne, Elizabeth, et. al. » Lorraine, posted by shelliR on September 7, 2001, at 22:08:05

Shelli
>
> re: oversleeping
> > Sounds like hypersomnia (my personal favorite when meds don't prevent it), which also falls in the category of atypical depression.
>
> well, don't most people who are depressed (and not simultaneously hyper) want to get in bed and pull the covers over their head when they are depressed?
> Is this only part of atypical depression

People without atypical depression may develop insomnia instead of over sleeping. Atypical includes symptoms of rejection sensitivity, over-eating, and a generally heavy feeling or "leaden paralysis".

> > >I can't imagine going on a vacation with a friend--too intense, although it would make me feel less vulnerable.

This is generally? You don't like vacationing with friends? And you feel uneasy vacationing alone--at least at times? (I'm not going to suggest tour groups.)

> > >Not out of fear, more out of laziness.

Not avoidance? My avoidance feels like laziness (leaden paralysis), but I suspect it's actually avoidance which is social anxiety based.


> > > One of my married friends has nothing in common with her husband; it's a very strange relationship (with no children, nor any planned). She is usually up to coming along, if I want to do something that I don't feel comfortable doing alone, like going to a concert. And I do that for her, also.

I do this with a friend. I've gone to Argentina and Santa Fe with her. It's kind of freeing to be without the family sometimes.


[re your hypertensive crises} Shelli I still have a headache (not severe) in the back of my skull and my neck is really stiff. This is Friday and the crises was Tuesday. Did this stuff linger for you also? I'm trying to figure out if this means that the hypertensive crises has not resolved or if these are residual effects of a hypertensive crises. Now, I can hear you say, what does it matter--why split that hair? Well, I want the hypertensive crises to be resolved before I start the Nardil.


> > You are making me think:-)
> Well thinking is good, right? :-)

Yes, it always is.

> > > I'll be anxious to see what he says and what his plan is :-)
>
> As long as the oxy is working , I am really not feeling depressed. I would like to increase the wellbutrin again. I'd do it tommrrow, but I don't want take any chance in messing up my last day here. I've put in a lot of time with the wellbutrin with no anti-depressant effects (I can tell because I wake still up still in a very bad depression until the morning oxy kicks in), but as long as I've hung in this long--I'd like to see what happens in another ten days or so, working up to 450mg.

It's interesting how much you are willing to stick with it on this one. Is it because it at least has no side effects?

> Good luck tomorrow with nardil.

I've decided to play it safe and wait at least one more day.

Lorraine

 

Re: Hypertensive crises, update » Lorraine

Posted by Elizabeth on September 8, 2001, at 21:05:09

In reply to Re: Hypertensive crises, update, posted by Lorraine on September 4, 2001, at 21:25:50

> Doing my washout from Parnate to Nardil with adderal and neurontin. Took 10 mg adderal this morning, fine. Took second 10 mg adderal this afternoon, started feeling funny. Tingling moving up my neck to my head and headache coming on, waited a little (not long) felt worse. Took blood pressure 165/97, i think.

That's about the point where I was instructed by my pdoc to take nifedipine. (BTW, "bite and swallow" seems to work better than SL.)

> Took antidote crushed it under tongue, blood pressure came down, right away and within an hour or so was clearly normal, although high for me on MAO. I feel very hungover. Not an experience I want to repeat necessarily.

Nifedipine made me feel hungover too.

-e

 

Re: Update Lorainne, Elizabeth, et. al. » Lorraine

Posted by shelliR on September 9, 2001, at 0:11:21

In reply to Re: Update Lorainne, Elizabeth, et. al. » shelliR, posted by Lorraine on September 8, 2001, at 12:53:48

Hi Lorraine,


> People without atypical depression may develop insomnia instead of over sleeping. Atypical includes symptoms of rejection sensitivity, over-eating, and a generally heavy feeling or "leaden paralysis".

Well, let's see. oversleeping-yes; overeating-no;
leaden paralysis-um, does horrible pain in the chest fit under leaden paralysis?


> > > >I can't imagine going on a vacation with a friend--too intense, although it would make me feel less vulnerable.
>
> This is generally? You don't like vacationing with friends? And you feel uneasy vacationing alone--at least at times? (I'm not going to suggest tour groups.)

well, I used to go to the beach with friends, and that was totally relaxing. I would never consider going to the beach by myself, and my body is definitely not bathing suit ready, anyway. I think it probably will never be again, anyway I much prefer the southwest mountains. Hint. I fell in love with it here when I came out for a few years to take photo workshops. And I keep coming back.

Except for a few *really* bad hate myself/want to die moments, it's been a very nice week for me. I don't feel lonely. And I don't think many friends would come here with and let me spend about a third of my time watching the US Open. The funny thing is I always come here during the US open; I would feel guilty watching so much and not working if I was at home, plus as I said it sort of connects me while I'm here.


> > > >Not out of fear, more out of laziness.
> Not avoidance? My avoidance feels like laziness (leaden paralysis), but I suspect it's actually avoidance which is social anxiety based.

Almost any social anxiety I have is related to being around single men. (Do I like them; do they like me, stuff.) Pretty much in other situations, I'm pretty comfortable. I hate doing things just to meet people, and most things I enjoy can be quite solitary. When you went to the depression groups, did the people seem interesting and depressed, or just depressed? (excluding the other babbler)
>
>

> I do this with a friend. I've gone to Argentina and Santa Fe with her.
hum, southwest mountains, art, not argentina.
as the game goes, getting pretty hot < g >.
>
>
> [re your hypertensive crises} Shelli I still have a headache (not severe) in the back of my skull and my neck is really stiff. This is Friday and the crises was Tuesday. Did this stuff linger for you also? I'm trying to figure out if this means that the hypertensive crises has not resolved or if these are residual effects of a hypertensive crises. Now, I can hear you say, what does it matter--why split that hair?

I don't even *get* the difference between residual effects and an unresolved hypertensive crisis. Really.

>Well, I want the hypertensive crises to be resolved before I start the Nardil.

Well, that makes sense, but you could also say you want to wait to start nardil until all the residual effects are gone. That's why I'm confused.

BTW, I had no residual effects after the episode. But my BP didn't go that high. For me I had a strong tightening of my shoulder muscles (well right on either side of my neck) and my pulse went way down. Looking back, I don't know how I even knew it was a hypertensive reaction. I had always heard a horrible headache in the back of the head. And I guess I was hypervigilent because my pdoc said she would not support my decision to try adrafinil, and I knew something felt different. It was the only stimulent I have tolerated, aside from concerta, which I have tried only recently. Concerta remains on my possible go back to list, along with nardil.
>
>
> > > > I'll be anxious to see what he says and what his plan is :-)
> > As long as the oxy is working , I am really not feeling depressed. I would like to increase the wellbutrin again....
>
> It's interesting how much you are willing to stick with it on this one. Is it because it at least has no side effects?

I guess so. That and the fact that I am not feeling desperate as soon as the oxy kicks in. Also, because this is how nardil felt. No side effects; long time to kick in. So it seems worth hanging in there; like not much to lose aside from getting myself up higher on oxy.

Another important factor is that I don't even have a clue what to try next, except to go back to nardil with oxy. Suggestions would be *greatly* appreciated. No antipsychcotics or tricyclics. I think I've tried every mood stabilizer.
>
>
>
> > Good luck tomorrow with nardil.
> I've decided to play it safe and wait at least one more day.

I probably would wait until the stiffness and headache go away if you can wait it out. Have you tried a muscle relaxer for the stiffness? (not a benzo, a real one :-)

Welcome back Elizabeth, if you read this. (and I hope and expect that you will). Any suggestions from you would also be appreciated. I see my pdoc monday, and I'm interested in what he has to say. My guess is that he'll have me continue the wellbutrin and up the dosage.

Shelli

 

Re: Update Lorainne, Elizabeth, et. al. » shelliR

Posted by Lorraine on September 9, 2001, at 12:46:15

In reply to Re: Update Lorainne, Elizabeth, et. al. » Lorraine, posted by shelliR on September 9, 2001, at 0:11:21

Hi Shelli:

> > [re atypical depression] People without atypical depression may develop insomnia instead of over sleeping. Atypical includes symptoms of rejection sensitivity, over-eating, and a generally heavy feeling or "leaden paralysis".
>
> Well, let's see. oversleeping-yes; overeating-no;
> leaden paralysis-um, does horrible pain in the chest fit under leaden paralysis?

I think by leaden paralysis they mean heaviness in the limbs. Elizabeth is the one who turned me on to the concept of atypical depression. It is useful to know because atypical depression apparently responds to MAOs well.

> > >[re vacationing alone] And I don't think many friends would come here with and let me spend about a third of my time watching the US Open. The funny thing is I always come here during the US open; I would feel guilty watching so much and not working if I was at home, plus as I said it sort of connects me while I'm here.

Only a very good friend would allow you to do this--but those are the only friends worth having anyway. With my husband, it took a while for us to learn that we don't have to do everything in tandem. It's harder to work out with friends b/c you are not around them so much I think, but it is the evolved way to relate. While you watch the US open, I'll be at the art galleries....

>
> > > When you went to the depression groups, did the people seem interesting and depressed, or just depressed? (excluding the other babbler)

Great question. I would say--it is a group of 25+ people--that of that group there are maybe 3 or 4 people that I might want to know. I've only gone 3 times so those 3 people may shift. If it turns out that there is only 1 person worth knowing, then I am a very lucky person anyway. What I need is to be in the "advanced" group, but there isn't one. My husband thinks I join these groups so that I can be a care-giver for those more needy, but what I would love is a group where people have already done a lot of intensive work and are stuggling with the day to day issues. Even the people that I don't want to befriend have some interesting points. Like a woman brought up the need for structure in our lives and talked about that. That is an important issue for me.

> > > Well, that makes sense, but you could also say you want to wait to start nardil until all the residual effects are gone. That's why I'm confused.

Yeah, ok, but a crick in the neck can take weeks to go away.


> > > Another important factor is that I don't even have a clue what to try next, except to go back to nardil with oxy. Suggestions would be *greatly* appreciated. No antipsychcotics or tricyclics. I think I've tried every mood stabilizer.

I'd be curious what elizabeth thinks of a Nardil and Desipramine combo.

> > >Have you tried a muscle relaxer for the stiffness? (not a benzo, a real one :-)

Aspirin work for the pain and Valium is a muscle relaxant.

In closing, Shelli, a little tennis gift for you, --a poem about Venus Williams by Al Letson Jr., who read it aloud at a Slam Poetry contest in Los Angeles and was kind enough to send me a copy of it.


The Second Planet From a Star
by Al Letson


I am waiting
for Venus Williams
to save me.

Like some
great Masi-Amazon warrior
stepping out the foliage
of the jungle,
to open green fields
outlined in white,
with sword in hand.
Prepared to do battle
using breath of flame.
spiting words like....

"I didn't come to play
good tennis,
I came to win!"

Beads,
singing like Medusa's hair
flailing against gravity
as tennis racket
hits the full moon
across the net,
and I'm stretch back
20 years
to an uncoordinated
painfully skinny kid
holding a tennis racket in hand
sweat saturating the grip
as the coach on the other side
of the court hollers

"YOU'RE PLAYING LIKE A GIRL, ALFIE!"

That's when I feel her slender fingers,
wrap around my shoulder,
and gently push me aside.

Eyes of marble and onyx
stare down the little man
across the net
and…… SERVE!

"Hummin' cummin' atcha'"

A little green globe
zooming through the atmosphere
narrowing in on it's target,
and at 100 miles per hour,
man, you better hit or get hit!

And he decides to get hit
BAM!!!

And I'm standing on the sideline
Screaming "15 LOVE!"
and don't know what the hell
I'm talking about.
as the goddess of love
stretches her statuesque arms in the air

and SERVE, and SERVE, and SERVE!!!

Calling forth hail stones
shaped like tennis balls,
to rain from the sky
pounding into his premature balding head
while he's screaming at the top of his lungs

STOP (BAM!)
STOP (BAM!)
STOP (BAM!)

and when she does,
she rocks back and forth
left to right,
waiting for the volley
that will never come.

Standing over the bully-coach.
I'm sayin'
"Who's playin' like a girl now?
Who's playin' like a girl now!?!?!"
What!!!"

and when I turn around,
she is gone.
The second planet from the star
we know so well.
flung back into the cosmos, where she belongs
leaving me to fast forward
twenty years,
back to the Future
to a man
slightly uncomfortable
with his height, weight,
and lack of athleticism
watching her on the TV screen,
as my daughter crawls on the floor
before me,
making me think of her.

Every time Venus whacks
another ball into the Stratosphere,
I'm caught up in the fact
that my daughter will face
obstacles I will never have to see
just because of her sex.

At that moment,
At that instant,
overcome by memories of an event
that never even happened,
I wanna grab my daughter up in my arms
and tell her,
tell her,

"Baby, these flawed genes
I pass down to you,
May not have the stuff of
Venus Williams, or Mia Hamm.
You may not write novels
like Edwidge Danticot,
Or Joyce Carol Oats.
You may never see the moon so close
you can almost smell it,
that you could taste it,
like May Jamison.
But wherever your talents lie
It will be beautiful,
and you will be beautiful
for who you are
weakness,
strengths
and all.

And if they ever tell you,
"your playing like a girl"
Be proud.
And know that you will win
like
a
woman. "

Lorraine

 

Re: Hypertensive crises, update » Elizabeth

Posted by Lorraine on September 10, 2001, at 20:24:39

In reply to Re: Hypertensive crises, update » Lorraine, posted by Elizabeth on September 8, 2001, at 21:05:09

> > Doing my washout from Parnate to Nardil with adderal and neurontin. Took 10 mg adderal this > > >[re hypertensive crises]Took blood pressure 165/97, i think.
>
> That's about the point where I was instructed by my pdoc to take nifedipine. (BTW, "bite and swallow" seems to work better than SL.)

I think if I had to do it over again, I would start the nifedipine right when the headache starts rather than based on the blood pressure. I still have a bit of a throbbing headache in the base of the back of my head. I don't know if this is hypertensive hangover; parnate withdrawal or a side effect of the nifedipine.

I did actually bite, put under the tongue for about 2 second and then swallowed.
>
> Nifedipine made me feel hungover too.
>

elizabeth: are you still on buprenorphine? Just wondering. Is the Desipramine still doing you good? Did you see the comment I made (earlier post--no need to go back to it tho) about augment Nardil with Desipramine or vica versa. Someone on the board reported good success with this.

I'm on to Nardil, started yesterday. No hypertensive episode so I'll call that success.


Lorraine

 

Re: Update Lorainne, Elizabeth, et. al. » Lorraine

Posted by shelliR on September 10, 2001, at 23:11:56

In reply to Re: Update Lorainne, Elizabeth, et. al. » shelliR, posted by Lorraine on September 9, 2001, at 12:46:15

Hi Lorraine,

Back from my vacation, and *not* relieved. All in all it was really nice. I was able to fight my insecurity enough to really enjoy the peace, beauty and art. It definitely is insecurity, not lonliness. I absolutely love dry heat and feel so much healthier in the SW, always. Of course, it was also wonderful to take a complete break from work. I saw such awesome photographs; it greatly greatly humbled me.

I think I might check out places in Arizona as a second base. (Still spending the majority of my time on the east coast.) If I can get some work there, and computer generate all my work, (the direction I am headed anyway), I might be able to break even on renting a little house/studio. (first rent; maybe later buy). I love the Santa Fe area, but it just gets too darn cold. Plus not the right population for my work, I don't think, although one of my clients moved out there and he manages Winton Marcelis. So I might have a in with the rich and famous. :-) You know, Ophrah, Jane Fonda, Julia Roberts, etc. HA. Near scottsdale is what I am thinking about in AZ.

> > > > When you went to the depression groups, did the people seem interesting and depressed, or just depressed? (excluding the other babbler)
> Great question. I would say--it is a group of 25+ people--that of that group there are maybe 3 or 4 people that I might want to know. I've only gone 3 times so those 3 people may shift. If it turns out that there is only 1 person worth knowing, then I am a very lucky person anyway. What I need is to be in the "advanced" group, but there isn't one. My husband thinks I join these groups so that I can be a care-giver for those more needy, but what I would love is a group where people have already done a lot of intensive work and are stuggling with the day to day issues. Even the people that I don't want to befriend have some interesting points. Like a woman brought up the need for structure in our lives and talked about that. That is an important issue for me.

Lucky, if you are getting something out of the group, and it sounds like you are-- minimally, at least.

> I'd be curious what elizabeth thinks of a Nardil and Desipramine combo.

Is that what you're looking toward with the nardil, if it's only partially effective?

> > > >Have you tried a muscle relaxer for the stiffness? (not a benzo, a real one :-)
> Aspirin work for the pain and Valium is a muscle relaxant.
Valium doesn't work for me (or most people) as a muscle relaxer. Or if it did, you have to take enough to pretty much knock you out. I've never heard of a doc giving valium anymore for muscle pulls, etc.; it's generally only used as a sedative now.
>
>
> In closing, Shelli, a little tennis gift for you, --a poem about Venus Williams by Al Letson Jr., who read it aloud at a Slam Poetry contest in Los Angeles and was kind enough to send me a copy of it.

Thanks. I liked reading it, though I imagine that hearing it and seeing who's reading it, has a fuller impact. I think the Williams sisters are pretty cool, especially considering their father. Mom must have had some influence re sensitivity.
>

So you have started nardil. So far, okay?

I will start nardil tomorrow with wellbutrin. Saw my pdoc today. He wanted to go to remeron next (with wellbutrin), and I burst out crying and said I want to go on nardil, again. He was a bit nervous about the combo. I have read on this site about two people who have done that combination. Someone said in a post last year that it is mentioned on Dr. Bob's psychobabble tips, but I couldn't find it. I'm going to look again, if I can't find it, I may e-mail Dr, Bob. Anyway, I realized after my appointment that I never asked him about taking an antidote. . He did check that I had a BP cuff, but that's about all. There is a more than minute chance for me to have a hypertensive reaction

So I went back in again, caught him in the hall, and he told me that I should watch for my diabolic BP going above 110. I have never even paid attention to that number, and I didn't get the opportunity to ask him why. Also, he said he didn't want me to take a nifedipine-type antidote and I should call him and go to the hospital.

I'm going fax him tomorrow and ask him what the deal is; why can't I have one--isn't that what they would give me at the hospital, anyway? He told me he responds to faxes because he checks them every fifteen minutes. I guess he doesn't check his messages. (?) Anyway, at least someone on this staff can tell me what he says. I really want to do this combo and am going to be totally bummed if I have a reaction. He said to start with 15mg tomorrow; I think I'll start with 7.5 or less.

When he left he said, "don't worry, I will make sure you get better." And I replied that he will blame me for not trying remeron. And then he said, "Please don't feel guilty, you are feeling bad enough. It's okay that you don't want to try remeron now." That was about the nicest thing he's ever said to me.

So now we are doing nardil together. BTW, I read your post to Elizabeth about taking the antidote earlier, but I think I might actually wait a bit longer. I think it may well be the nifedipine that made you sick and maybe you could have waited a little longer to see if it was still going up. I don't know, but that's a possiblity. I did some research before on nifedipine with MAOIs and there are really contrary views about giving it to patients. If I remember correctly (and I may not, really), I think some pdocs think their MAOI patients might take it too early and then the nifedipine might make them very sick.

I don't remember how bad your headache was, though. My reaction was shoulder tightness, so there was no real pain involved. But you might ask your pdoc about exactly when he thinks you should take it. I don't know how fast it works ; I guess that would determine how high to go up before taking the antidote.

What dose did you start with nardil?

later, keep me posted,

Shelli

 

Re: Update Lorainne, Elizabeth, et. al. » shelliR

Posted by Lorraine on September 11, 2001, at 13:10:13

In reply to Re: Update Lorainne, Elizabeth, et. al. » Lorraine, posted by shelliR on September 10, 2001, at 23:11:56

Hi Shelli,

Back from my vacation, and *not* relieved.

That's a good sign:-0

It definitely is insecurity, not lonliness.

Yeah, I rarely, rarely get lonely. Insecurity about being alone?

I love the Santa Fe area

Me too. I wasn't wild about Sedona though.

but it just gets too darn cold. Plus not the right population for my work, I don't think, although one of my clients moved out there and he manages Winton Marcelis. So I might have a in with the rich and famous. :-) You know, Ophrah, Jane Fonda, Julia Roberts, etc. HA.

I don't know--the tourists might be interested, but it might entail a different work schedule or mailing prints when done. There is a ton of foot traffic.

> > I'd be curious what elizabeth thinks of a Nardil and Desipramine combo.
>
> Is that what you're looking toward with the nardil, if it's only partially effective?

It's what I think is the next obvious step. I started Nardil at 15 mg and, of course, like it very much. (I know I'm not supposed to be able to tell, but I do feel a slight boost and I do feel more hunger than usual.) So as usual I'm optimistic. I guess that's fine--this random walk through pharmacology. May as well be optimistic.


> > > > >Have you tried a muscle relaxer for the stiffness? (not a benzo, a real one :-)
> > Aspirin work for the pain and Valium is a muscle relaxant.
> Valium doesn't work for me (or most people) as a muscle relaxer

I've only needed the valium at night--it knocks me out anyway even splitting the smallest tablet. But the stiffness and headache seem better whether this is because I have another MAO in my system or because time heals, I don't know.


> > >I imagine that hearing it and seeing who's reading it, has a fuller impact. I'm sure you are right. The guy who wrote it was a slight black man who had two daughters.

> > > I will start nardil tomorrow with wellbutrin. Saw my pdoc today. He wanted to go to remeron next (with wellbutrin), and I burst out crying and said I want to go on nardil, again. He was a bit nervous about the combo. I have read on this site about two people who have done that combination.
I don't know of anyone on that combo though I am sure someone here has tried it

Anyway, I realized after my appointment that I never asked him about taking an antidote. . He did check that I had a BP cuff, but that's about all. There is a more than minute chance for me to have a hypertensive reaction So I went back in again, caught him in the hall, and he told me that I should watch for my diabolic BP going above 110. I have never even paid attention to that number, and I didn't get the opportunity to ask him why. Also, he said he didn't want me to take a nifedipine-type antidote and I should call him and go to the hospital.

Shelli-- I was in genuine pain, excruciating headache, intense throbbing at the base of my skull--I still have slight remnants of it. I would be very uncomfortable without the antidote. So you call him and he acalls you back in fifteen minutes or worse it's half an hour and you are in the emergency room and they are making you wait. It just seems to happen very quickly and I know elizabeth had a bad experience in the emergency room. I'm aware of the controvery re the antidote. There is actually a good discussion of it in the tips section--a rebutttal to the concerns that I thought was pretty convincing. I think that doctors follow standard medical procedures until it's their head and then they take the antidote. (Isn't that a vicious thought?)


>
> > >I'm going fax him tomorrow and ask him what the deal is; why can't I have one--isn't that what they would give me at the hospital, anyway?

Good.

> > >He said to start with 15mg tomorrow; I think I'll start with 7.5 or less.

I thought the lowest dose was 7.5 mg and my pharmicist told me that I could not split the tablets--he could be wrong, but you might want to check.

> > > So now we are doing nardil together. BTW, I read your post to Elizabeth about taking the antidote earlier, but I think I might actually wait a bit longer. I think it may well be the nifedipine that made you sick and maybe you could have waited a little longer to see if it was still going up. I don't know, but that's a possiblity.

You know what I ought to do a search for it here and if that comes up dry post it as a general question. It is a very good point--whether the antidote itself makes you ill.


> > >But you might ask your pdoc about exactly when he thinks you should take it.

He said at the first sign of an intensive headache that didn't feel like any headache I had ever had. But then I read an old post of elizabeth's saying something like bp of 165/95 and I followed that instead.

> > >I don't know how fast it works ; I guess that would determine how high to go up before taking the antidote.


It's pretty quick. I don't know how long unmedicated hypertensive crises last ordinarily.


Good luck to you shelli on the Nardil combo. I'm glad your pdoc was able to sympathize with you--it was a big step for him and made you feel better to boot. :-)

Lorraine

 

Re: Update » shelliR

Posted by Elizabeth on September 12, 2001, at 3:43:08

In reply to Re: Update Lorainne, Elizabeth, et. al. » Lorraine, posted by shelliR on September 9, 2001, at 0:11:21

> Well, let's see. oversleeping-yes; overeating-no;
> leaden paralysis-um, does horrible pain in the chest fit under leaden paralysis?

Probably not. Leaden paralysis means your body, especially arms and legs, feels really heavy.

> I don't even *get* the difference between residual effects and an unresolved hypertensive crisis. Really.

The difference would be whether your blood pressure is still high! (People whose BP runs low seem to have worse symptoms than those with higher baseline BPs.)

> BTW, I had no residual effects after the episode. But my BP didn't go that high. For me I had a strong tightening of my shoulder muscles (well right on either side of my neck) and my pulse went way down.

That's a compensatory measure: your heart is attempting to compensate for the vasoconstriction by decreasing its output.

> Looking back, I don't know how I even knew it was a hypertensive reaction.

It probably was, though it may not have been a true "crisis." Since you've been having possible reactions, I really suggest that you try to find a BP monitor so that you can check these things. The digital self-inflating ones are expensive but a manual one should only run about $15-25.

> I had always heard a horrible headache in the back of the head.

That's the main one, yeah.

> No antipsychcotics or tricyclics.

What did these do when you tried them (if you did)?

> I think I've tried every mood stabilizer.

Tegretol? Trileptal? Keppra?

> I probably would wait until the stiffness and headache go away if you can wait it out. Have you tried a muscle relaxer for the stiffness? (not a benzo, a real one :-)

Soma, perhaps.

> Welcome back Elizabeth, if you read this.

Thanks. :-) I'm slowly catching up.

-elizabeth

 

Re: Update » Lorraine

Posted by Elizabeth on September 12, 2001, at 3:47:17

In reply to Re: Update Lorainne, Elizabeth, et. al. » shelliR, posted by Lorraine on September 9, 2001, at 12:46:15

> Yeah, ok, but a crick in the neck can take weeks to go away.

I don't think it's a crick -- that is, it's not musculoskeletal, but vascular.

> I'd be curious what elizabeth thinks of a Nardil and Desipramine combo.

It could be worth a try, and I think it would be safe (although I'd suggest monitoring your BP closely). I haven't had any appetite loss on desipramine, so I'm not sure it would counteract the weight gain from Nardil very effectively.

-elizabeth

 

Re: Hypertensive crises, update » Lorraine

Posted by Elizabeth on September 12, 2001, at 3:51:20

In reply to Re: Hypertensive crises, update » Elizabeth, posted by Lorraine on September 10, 2001, at 20:24:39

> > > Doing my washout from Parnate to Nardil with adderal and neurontin. Took 10 mg adderal this > > >[re hypertensive crises]Took blood pressure 165/97, i think.
> >
> > That's about the point where I was instructed by my pdoc to take nifedipine. (BTW, "bite and swallow" seems to work better than SL.)
>
> I think if I had to do it over again, I would start the nifedipine right when the headache starts rather than based on the blood pressure.

I wouldn't. People have differing levels of reactivity depending on various factors (e.g., baseline BP). You want to have a number, you know? It's a bad idea to take nifedipine if you aren't sure that your BP has reached a certain level. Also, although it's high, 160-170/90-100 isn't terribly dangerous -- it's just a good safe point to take nifedipine if the BP is still rising.

> I did actually bite, put under the tongue for about 2 second and then swallowed.

That sounds like a great compromise. :-)

> elizabeth: are you still on buprenorphine?

Yup.

> Is the Desipramine still doing you good?

Yes, it is.

-elizabeth

 

Re: Update » shelliR

Posted by Elizabeth on September 12, 2001, at 4:06:26

In reply to Re: Update Lorainne, Elizabeth, et. al. » Lorraine, posted by shelliR on September 10, 2001, at 23:11:56

> Valium doesn't work for me (or most people) as a muscle relaxer. Or if it did, you have to take enough to pretty much knock you out. I've never heard of a doc giving valium anymore for muscle pulls, etc.; it's generally only used as a sedative now.

Some doctors try to pass it off as a muscle relaxer.

> I will start nardil tomorrow with wellbutrin. Saw my pdoc today. He wanted to go to remeron next (with wellbutrin), and I burst out crying and said I want to go on nardil, again. He was a bit nervous about the combo.

Honestly, I think it's safe. I've heard of a number of people who tried it with no ill effects, and I've *NEVER* heard of any noticeable interaction.

> So I went back in again, caught him in the hall, and he told me that I should watch for my diabolic BP going above 110.

"Diabolic?" You mean diastolic, right? < g >

> I have never even paid attention to that number, and I didn't get the opportunity to ask him why.

It means that your heart's "at rest" state is resulting in a high pressure.

> Also, he said he didn't want me to take a nifedipine-type antidote and I should call him and go to the hospital.

I don't agree, but I understand his reasoning.

> I'm going fax him tomorrow and ask him what the deal is; why can't I have one--isn't that what they would give me at the hospital, anyway?

No, they'd give you phentolamine or nitroprusside. They'd also monitor you to make sure you were okay (no BP crash, etc.).

> When he left he said, "don't worry, I will make sure you get better." And I replied that he will blame me for not trying remeron. And then he said, "Please don't feel guilty, you are feeling bad enough. It's okay that you don't want to try remeron now." That was about the nicest thing he's ever said to me.

I think that's really sweet of him.

> I did some research before on nifedipine with MAOIs and there are really contrary views about giving it to patients.

I think that many doctors really need to have confidence that you know what you're doing before they'll give you nifedipine. It does have its dangers.

> If I remember correctly (and I may not, really), I think some pdocs think their MAOI patients might take it too early and then the nifedipine might make them very sick.

Yes. It can make your blood pressure "crash," which can progress to shock (worst-case scenario).

> I don't know how fast it works ; I guess that would determine how high to go up before taking the antidote.

IME, about 10-15 minutes when taken by "bite & swallow."

-e

 

Re: Update Lorainne, Elizabeth, et. al. » Lorraine

Posted by shelliR on September 12, 2001, at 22:21:30

In reply to Re: Update Lorainne, Elizabeth, et. al. » shelliR, posted by Lorraine on September 11, 2001, at 13:10:13

Hi Lorraine,
>
> Back from my vacation, and *not* relieved.
> That's a good sign:-0
> It definitely is insecurity, not lonliness.
> Yeah, I rarely, rarely get lonely. Insecurity about being alone?
Thinking something is wrong with me because none of my relationships worked out and not even certain that I want to try again. The old shame thing again.

> I love the Santa Fe area
> Me too. I wasn't wild about Sedona though.

Did you go to Arizona on the same trip? Interesting. I've never been to Sedona, but many people have told me it's very magical. What was it that you didn't like about it?

I don't love Santa Fe or even Taos per say; I love the weather, I love the tremendous range of visual art, and I love driving out there: total overwhelming beauty in every direction.. And I do like the friendliness, especially the curtesy in driving. I mean, you signal, and people actually let you change lanes. And it completely awesome to realize that one woman (Mable Dodge) encouraged artists to come out there--really at that time in the middle of nowhere. Of course O’Keefe, but also Willa Cather and D.H. Lawrence among others, even from Europe.

On the topic of art, I would miss the general lack of culture there, not much music, independent film, concerts besides the opera. It is increasing, but it feels pretty much a void after all the access in D.C. and the closeness to NYC. I actually don’t go to NY very often, last went for the Edward Hopper exhibit; he’s probably my favorite painters of all time. At last, we have one or two direct flights a day which makes it now much much easier to get there and back without wasting two days. Maybe next year my sister and niece will come with me, if I go back. My sister and I can't spend too much time together without getting on each others' nerves. (hey, you want to meet me in santa fe next summer? :-) )

> but it just gets too darn cold. Plus not the right population for my work, I don't think, although one of my clients moved out there and he manages Winton Marcelis. So I might have a in with the rich and famous. :-) You know, Ophrah, Jane Fonda, Julia Roberts, etc. HA.
> I don't know--the tourists might be interested, but it might entail a different work schedule or mailing prints when done. There is a ton of foot traffic.

I don't see it as a good place for my type of work. They would have to be quick, tacky pictures, because I don't think people on vacation would find it important to spend several hours with a photographer while on vacation. I know , I wouldn't. I can't particularly envision mountain pictures in the same way I have seen beautiful beach pictures. I love simplicity. My niece once had a school picture done in what looked to me like the alps behind her. Very bizarre background for a school photo. I always wonder: "what are these photographers thinking?" Are California school pictures as strange?

> It's what I think is the next obvious step. I started Nardil at 15 mg and, of course, like it very much. (I know I'm not supposed to be able to tell, but I do feel a slight boost and I do feel more hunger than usual.) So as usual I'm optimistic. I guess that's fine--this random walk through pharmacology. May as well be optimistic.

I think nardil is a great antidepressant, and since you obviously respond to MAOIs (based on your parnate experience), I think you *should * be very optimistic. And since your body is so sensitive, you probably are perceiving some AD effect.
>
>
> Anyway, I realized after my appointment that I never asked him about taking an antidote. . He did check that I had a BP cuff, but that's about all. There is a more than minute chance for me to have a hypertensive reaction So I went back in again, caught him in the hall, and he told me that I should watch for my diabolic BP going above 110. I have never even paid attention to that number, and I didn't get the opportunity to ask him why. Also, he said he didn't want me to take a nifedipine-type antidote and I should call him and go to the hospital.
Shelli-- I was in genuine pain, excruciating headache, intense throbbing at the base of my skull--I still have slight remnants of it. I would be very uncomfortable without the antidote. So you call him and he acalls you back in fifteen minutes or worse it's half an hour and you are in the emergency room and they are making you wait. It just seems to happen very quickly and I know elizabeth had a bad experience in the emergency room. I'm aware of the controvery re the antidote. There is actually a good discussion of it in the tips section--a rebutttal to the concerns that I thought was pretty convincing. I think that doctors follow standard medical procedures until it's their head and then they take the antidote. (Isn't that a vicious thought?)

Well I saw my pdoc again today, because I have plummeted down in the last two days and we were talking hospitalization. Again. I am now pretty sure it has to do with the horror of yesterday piled up on top of my depression. I couldn’t trace it though, until I read a post from Anna (sweetmarie) saying how she had definitely experienced a downward plunge, after the news. And she’s in the UK! Monday I was fine; Tuesday afternoon I was seriously contemplating suicide and today woke up severely hopeless. I have to start working again Friday—it was supposed to be today, but there was luckily a cancellation due to the airports closing and the client being out of town. I am very shaky and not sure that I can handle work.

Anyway, I did get to talk to my pdoc about the antidote. His feeling is that I will not have an immediate reaction. Sort of like last time, if I do have a reaction—where it went up to 168 and then back down within minutes. That it takes a buildup of a drug combination to get you into the stoke range, and if you pay attention to the signals, you will not get there. I am trusting him on this because he has no reason not to be completely frank with me. My friend had several hypertensive reactions with bad headaches and it was pretty scary how long they took to get to her at the hospital. I took her there once after she had a reaction to ale and was appalled. But her BP also never went over 170. I do have a blood cuff with me now at all times, until I am passed any danger point, and it if comes down to it I would not feel self-conscious bypassing triage and walking right into the ER and demanding attention.


> > > >He said to start with 15mg tomorrow; I think I'll start with 7.5 or less.I >thought the lowest dose was 7.5 mg and my pharmacist told me that I could not split the tablets--he could be wrong, but you might want to check.

Too late, I already took a split pill. It’s not time release so I can’t imagine why there would be a problem. The lowest dose is 15mg. Today a whole pill, no problem, but I will continue to keep watch, especially because I will raise it on Friday to 22.5mg then Sunday to 30mg. And I have very much in mind that a buildup over several days might cause a problem. That was the case with adrafinil. It took several days until I felt a reaction, but didn’t have any physical signs and didn’t have a BP cuff. I am very hopeful that there will be no problems.
>


>It is a very good point--whether the antidote itself makes you ill.
That is the impression in my reading and also from my pdoc.

So day three, any more news? When are you going to raise your dose and do you have any idea of how high you are intending to go? I started on 45mg (well, within one week, if I remember right), but generally through the years I have kept my dose at 30mg because of sleep disturbances which were minimal at 30mg. I also had very strange and scarey experiences not adjusting to natural light changes (especially from inside to outdoor sunlight) when I had been on 45mg for about six months.

Were the schools closed in California? They were closed, of course, in NY, but I was suprised that the D.C. and Philadelphia schools were closed. Maybe out of respect? I don't really understand why; I'll have to go back to the metro section of the Post.

BTW, before the horror of yesterday, how was being alone all day, with the kids in school?

Take care, Shelli

 

Re: Hypertensive crises, update » Elizabeth

Posted by Lorraine on September 13, 2001, at 11:06:20

In reply to Re: Hypertensive crises, update » Lorraine, posted by Elizabeth on September 12, 2001, at 3:51:20

9/12/01 elizabeth to Shelli

> > I don't even *get* the difference between residual effects and an unresolved hypertensive crisis. Really.
>
Ø The difference would be whether your blood pressure is still high! (People whose BP runs low seem to have worse symptoms than those with higher baseline BPs.)

Elizabeth, help me understand this. When you have a hypertensive crises your blood pressure shoots up because of vascular contraction (veins get smaller) and your pulse rate decreases to compensate for this. When you take the antidote, it lowers the blood pressure by dilating the veins and the pulse rate returns to normal? (I’m sure my language is all wrong, but you get the gist.) So that crick in my neck was probably the result of residual the vascular contraction in that area. It would make sense, although my BP came down very significantly (well within the average range) after the antidote it did not return to pre-hypertensive readings (which were low because the Parnate had decreased my BP readings generally) until about 5 days later.
.
9/12/01 elizabeth to Lorraine

> > I'd be curious what elizabeth thinks of a Nardil and Desipramine combo.
>
Ø It could be worth a try, and I think it would be safe (although I'd suggest monitoring your BP closely). I haven't had any appetite loss on desipramine, so I'm not sure it would counteract the weight gain from Nardil very effectively.

Thanks for the info. Just want to have a next step in mind if the Nardil doesn’t do it. I know I am jumping the gun so to speak but it makes me feel better emotionally to do this. Then when things don’t work out, I don’t panic or go too low, but just take the next step and distract myself.

9/12/01 elizabeth to Lorraine (msg 2)

> > > > Doing my washout from Parnate to Nardil with adderal and neurontin. Took 10 mg adderal this > > >[re hypertensive crises]Took blood pressure 165/97, i think.
> > >
Ø > > That's about the point where I was instructed by my pdoc to take nifedipine. (BTW, "bite and swallow" seems to work better than SL.)

I had searched Psychobabble and believe that I found a post of yours saying your pdoc had used these levels.

> >
> > I think if I had to do it over again, I would start the nifedipine right when the headache starts rather than based on the blood pressure.
>
Ø I wouldn't. People have differing levels of reactivity depending on various factors (e.g., baseline BP). You want to have a number, you know? It's a bad idea to take nifedipine if you aren't sure that your BP has reached a certain level. Also, although it's high, 160-170/90-100 isn't terribly dangerous -- it's just a good safe point to take nifedipine if the BP is still rising.

I know, it’s just that it took so long for the episode to fully resolve. I was very out of sorts (although functional) for a good 5 days. I felt like I’d been in an auto accident and had whiplash. (Although I don’t suppose you’d know how that felt? How are the driving lessons going?)

> > Is the Desipramine still doing you good?
>
Ø Yes, it is.

I am so pleased to hear this Elizabeth.


9/12/01 elizabeth to Shelli

> > So I went back in again, caught him in the hall, and he told me that I should watch for my diabolic BP going above 110.
>
Ø "Diabolic?" You mean diastolic, right? < g >

I thought she was referring to him when she said diabolic < vbg >.

> > I'm going fax him tomorrow and ask him what the deal is; why can't I have one--isn't that what they would give me at the hospital, anyway?
>
Ø No, they'd give you phentolamine or nitroprusside. They'd also monitor you to make sure you were okay (no BP crash, etc.).

Yes, but aren’t you looking at a significant delay to treatment (driving to the hospital; getting admitted; having them draw blood to make sure you’re not on cocaine?; treating you like an idiot?) Bad attitude, I know.


> > If I remember correctly (and I may not, really), I think some pdocs think their MAOI patients might take it too early and then the nifedipine might make them very sick.
>
Ø Yes. It can make your blood pressure "crash," which can progress to shock (worst-case scenario).

OK, I’ll be careful. Elizabeth, how long to hypertensive crises usually last? I thought about taking another BP reading 5 minutes after my high one to see if it was coming down, but got too scared to wait.

Lorraine

 

Re: Update Lorainne, Elizabeth, et. al. » shelliR

Posted by Lorraine on September 13, 2001, at 11:53:33

In reply to Re: Update Lorainne, Elizabeth, et. al. » Lorraine, posted by shelliR on September 12, 2001, at 22:21:30

Shelli,

Insecurity about being alone?
> Thinking something is wrong with me because none of my relationships worked out and not even certain that I want to try again. The old shame thing again.

I'm sorry to hear that. I know first hand how difficult shame can be to deal with.

> Did you go to Arizona on the same trip? Interesting. I've never been to Sedona, but many people have told me it's very magical. What was it that you didn't like about it?

Well, I loved the place we ended up staying at (don't remember the name--some exclusive resort type of place that my airline friend got for a song). Otherwise, I just wasn't inspired by the rest of Sedona--the landscape did not send me (it reminded me of California desert but red) and I missed the culture of Sante Fe. I am definately in the minority. I've been to Phoenix and it was OK. I've been on Lake Powell and that was beautiful.

> On the topic of art, I would miss the general lack of culture there, not much music, independent film, concerts besides the opera. It is increasing, but it feels pretty much a void after all the access in D.C. and the closeness to NYC. I actually don’t go to NY very often

I lived in DC for a summer as a law intern. Loved it. Might not want to live there because I suspect it's a bit provicial for all it's big city trappings--at least it was then (25 years ago).


(hey, you want to meet me in santa fe next summer? :-) )

I thought you didn't like meeting psychobabblers;-). I don't know how our summer plans are shaping up (what with the kids and all summer gets crazy). But I might go to the east coast next summer. If I do, we might get together.


> I don't see it as a good place for my type of work. They would have to be quick, tacky pictures, because I don't think people on vacation would find it important to spend several hours with a photographer while on vacation.

You're right.
My niece once had a school picture done in what looked to me like the alps behind her. Very bizarre background for a school photo. I always wonder: "what are these photographers thinking?" Are California school pictures as strange?

Yes, very strange. No Alps thought, but I have not gotten a good picture of the kids from the school photographer.



> I think nardil is a great antidepressant, and since you obviously respond to MAOIs (based on your parnate experience), I think you *should * be very optimistic. And since your body is so sensitive, you probably are perceiving some AD effect.
> >

One hopes.


> > > Well I saw my pdoc again today, because I have plummeted down in the last two days and we were talking hospitalization. Again.

I'm so sorry to hear this. You are going through a terribly rough patch, right now. Eventually, it will get better. The hard part is that you (and I) don't even know if we are on the right meds now and the urge to find an answer is so strong; it's easy to just move on before the right med has a chance to work (Nardil took 5 weeks for you--I just finished 5 weeks on Parnate.) It's the old advice shelli, when you are depressed don't look at the big picture only focus on details or distract yourself. This is a terrible time to try to distract yourself with TV though. I know you know all this, still...

I am now pretty sure it has to do with the horror of yesterday piled up on top of my depression. I couldn’t trace it though, until I read a post from Anna (sweetmarie) saying how she had definitely experienced a downward plunge, after the news.

I've been feeling this too. I try not to listen to the news too much. My husband wants it on all the time, but I feel like climbing out of my skin when it's on so much. I reorganized the cabinets in the house to distract myself. I definately need to distract myself from this--I have no tolerance for stress and this is definately stressful. Avoidance is how I now deal with stress. I try to insulate myself from it. I have to. I've thought of looking at churches to attend actually, although I am not religious, I just think the structure, the ritual, the "words" might be soothing now.

> >I am very shaky and not sure that I can handle work.

So this is a photo shoot. Long time commitment. And you don't just get lost in the work once you start? Photo shooting sounds like the essence of detail and distraction to me if you are up to it.

That it takes a buildup of a drug combination to get you into the stoke range, and if you pay attention to the signals, you will not get there. ...if comes down to it I would not feel self-conscious bypassing triage and walking right into the ER and demanding attention.

That's great. My reaction came after 5 weeks on Parnate (which is more prone to causing hypertensive crises) and was in reaction to adding stimulants (although the day I took the Adderal I was off the Parnate, still it was in my system) and I added too much stimulant (really, I went full dose on day one) So in retrospect I was really being careless. I have a new respect for drugs, now, of course. :-)

> > > Too late, I already took a split pill. It’s not time release so I can’t imagine why there would be a problem.

Well, I was told I could split Parnate so I don't understand why not either. I think the pharmacist was just unwilling to look it up. I'm glad it worked out.

The lowest dose is 15mg. Today a whole pill, no problem, but I will continue to keep watch, especially because I will raise it on Friday to 22.5mg then Sunday to 30mg. And I have very much in mind that a buildup over several days might cause a problem.

Wow, you are moving fast. I need to increase my dose of Nardil (still 15 mg) but am a bit anxious about doing it. Do you remember if you had any anxiety when you were beginning Nardil?

> So day three, any more news? When are you going to raise your dose and do you have any idea of how high you are intending to go? I started on 45mg (well, within one week, if I remember right), but generally through the years I have kept my dose at 30mg because of sleep disturbances which were minimal at 30mg.

I'll probably go to 1 1/2 pills today this is how sure I am that my pharmacist was not right). I probably won't get to a very high dose. I'd be surprised if I go over 30 mg.

I also had very strange and scarey experiences not adjusting to natural light changes (especially from inside to outdoor sunlight) when I had been on 45mg for about six months.

Wellbutrin caused me to have visual trails and made lights dance--especially coming from a dark space (movie theatre or waking up) to a light space (movie theatre restroom).


> Were the schools closed in California?

It was up to the parents and we took the kids to school to maintain a sense of normalacy. Their school were not near location that I thought would be potential targets and they are fairly close by.

> > > BTW, before the horror of yesterday, how was being alone all day, with the kids in school?

You know I like being alone. And I have been so busy--I'm painting the house and so forth. Also when I drive the kids, the other parents pull me aside and talk to me. They like me :-) So I'm actually a bit more social than usual.


Lorraine

 

Re: Hypertensive crises, update » Lorraine

Posted by Elizabeth on September 13, 2001, at 14:43:22

In reply to Re: Hypertensive crises, update » Elizabeth, posted by Lorraine on September 13, 2001, at 11:06:20

> > > I don't even *get* the difference between residual effects and an unresolved hypertensive crisis. Really.
> >
> Ø The difference would be whether your blood pressure is still high! (People whose BP runs low seem to have worse symptoms than those with higher baseline BPs.)

So you mean by "residual effects" continued symptoms after BP has returned to normal? I wouldn't expect any such symptoms, unless the HT did damage.

Calcium channel blockers, like nifedipine, lower your BP by dilating blood vessels. Sometimes this can cause your body to try to compensate by raising your pulse. This is why treating hypertension is so complicated and often requires elaborate drug cocktails: the cardiovascular system tries to maintain its homeostasis by compensating for the effects of drugs.

> So that crick in my neck was probably the result of residual the vascular contraction in that area.

I don't know exactly what causes the particular symptoms, for the most part.

> It would make sense, although my BP came down very significantly (well within the average range) after the antidote it did not return to pre-hypertensive readings (which were low because the Parnate had decreased my BP readings generally) until about 5 days later.

How high was it for those 5 days before it went back to normal?

> Thanks for the info. Just want to have a next step in mind if the Nardil doesn’t do it. I know I am jumping the gun so to speak but it makes me feel better emotionally to do this. Then when things don’t work out, I don’t panic or go too low, but just take the next step and distract myself.

One thing you might want to consider is that TCAs don't work very well for atypical depression. It might be worth a try, but there might be something else that's more likely to help.

> > ...although it's high, 160-170/90-100 isn't terribly dangerous -- it's just a good safe point to take nifedipine if the BP is still rising.
>
> I know, it’s just that it took so long for the episode to fully resolve. I was very out of sorts (although functional) for a good 5 days. I felt like I’d been in an auto accident and had whiplash. (Although I don’t suppose you’d know how that felt? How are the driving lessons going?)

Dude, I don't have a license, but it's not like I've never ridden in a car! < g > I think it is weird that it took so long for it to go away completely. Some people just seem to be more sensitive to side effects than the average person is.

> > > Is the Desipramine still doing you good
> >
> Ø Yes, it is.
>
> I am so pleased to hear this Elizabeth.

Thank you. I'm pleased to say it.

> Ø No, they'd give you phentolamine or nitroprusside. They'd also monitor you to make sure you were okay (no BP crash, etc.).
>
> Yes, but aren’t you looking at a significant delay to treatment (driving to the hospital; getting admitted; having them draw blood to make sure you’re not on cocaine?; treating you like an idiot?) Bad attitude, I know.

When I showed up at an ER (or at the MIT Medical Center) with high blood pressure, I got seen at once. (MIT Medical didn't actually help me in any way, but they did monitor my BP -- they didn't just tell me to sit in the waiting room.) I think it's worth it to get a portable BP monitor (they'll fit in a reasonable-sized purse or handbag) so you can check it if you start getting symptoms.

> Ø Yes. It can make your blood pressure "crash," which can progress to shock (worst-case scenario).
>
> OK, I’ll be careful.

Thanks. I would hate for something like that to happen to you.

> Elizabeth, how long to hypertensive crises usually last? I thought about taking another BP reading 5 minutes after my high one to see if it was coming down, but got too scared to wait.

I think they usually resolve within a few hours, but I might be misremembering.

-elizabeth

 

Re: Update Lorainne, Elizabeth, et. al. » Lorraine

Posted by shelliR on September 14, 2001, at 11:06:10

In reply to Re: Update Lorainne, Elizabeth, et. al. » shelliR, posted by Lorraine on September 13, 2001, at 11:53:33

Hi Lorraine,
>

> I lived in DC for a summer as a law intern. Loved it. Might not want to live there because I suspect it's a bit provicial for all it's big city trappings--at least it was then (25 years ago).

I think it's probably still true in lawyer circles and some other work type situations, but I'm not much connected to that world. I imagine though in general, it is more formal. Like I wouldn't ever go into the city wearing shorts, even discounting my age and my enlarged body. Like in Santa Fe, all bodies wore shorts. :-) (or western hippie attire.)

>
> (hey, you want to meet me in santa fe next summer? :-) )
> I thought you didn't like meeting psychobabblers;-). I don't know how our summer plans are shaping up (what with the kids and all summer gets crazy). But I might go to the east coast next summer. If I do, we might get together.

Well, I actually I don't think I was serious. And I'm still not feeling like bringing board life into real life. I am too vulnerable now, and need to stay light. Today I got an invitation to come out to Sierra Vista, AZ, which is supposed to be quite beautiful. The invite was from a client who just moved out there, but I don't know them well; just photographed them once recently. So I wouldn't feel comfortable taking her up on it, although I would call them if I get out there.

I meet a lot of interesting people doing what I do, but they are generally in a very different life situation, so although we like each other very much, the friendship doesn't extend into private social interactions, generally, although there have been exceptions. Interestingly, the exceptions are generally from the UK--I think they are more open about who they invite to their parties; they seem to enjoy diversity.

> > > > Well I saw my pdoc again today, because I have plummeted down in the last two days and we were talking hospitalization. Again.
> I'm so sorry to hear this. You are going through a terribly rough patch, right now. Eventually, it will get better. The hard part is that you (and I) don't even know if we are on the right meds now and the urge to find an answer is so strong; it's easy to just move on before the right med has a chance to work (Nardil took 5 weeks for you--I just finished 5 weeks on Parnate.) It's the old advice shelli, when you are depressed don't look at the big picture only focus on details or distract yourself. This is a terrible time to try to distract yourself with TV though. I know you know all this, still..

Well, I've never used TV as a distraction. It doesn't engage enough of my mine for it to be a distraction. Although watching tennis is a large distraction for me (and it doesn't engage my mind either). If I can get into reading, that engages me more than anything, and it's good if I am already into a book so it doesn't involve transition.

I have not done any work this week so far, including printing, etc. I finally started returning phone calls today. I also had a few conversations with my sister (out of state) and can feel her concern and just talked to my therapist friend for about an hour on the phone, about therapy; sort of her view as a therapist; do any patients make her feel insecure, etc. It sounds like she feels very confident in her work and enjoys it quite a bit. She is working with more children recently and finds the pressure much greater. This is because of the part their parents play in creating (or reinforcing) their problems, and also because, sort of what you say about your kids, they are only this age once. You don't want them to have to compensate later for missing a developmental stage, so there is much a more immediate need to get them on track. It's always interesting to talk to her. She's about the only friend that I talk about medication with, more than just mentioning that it has changed again.
>

> I am now pretty sure it has to do with the horror of yesterday piled up on top of my depression. I couldn’t trace it though, until I read a post from Anna (sweetmarie) saying how she had definitely experienced a downward plunge, after the news.
> I've been feeling this too. I try not to listen to the news too much. My husband wants it on all the time, but I feel like climbing out of my skin when it's on so much. I reorganized the cabinets in the house to distract myself. I definately need to distract myself from this--I have no tolerance for stress and this is definately stressful. Avoidance is how I now deal with stress. I try to insulate myself from it. I have to. I've thought of looking at churches to attend actually, although I am not religious, I just think the structure, the ritual, the "words" might be soothing now.

I tried that years ago, and never found that, unfortunately. I have always had a hard time identifying with groups that I can't embrace completely. Sometimes that is not a good way to be, but I think it's just a part of my makeup.
>
> > >I am very shaky and not sure that I can handle work.
>
> So this is a photo shoot. Long time commitment. And you don't just get lost in the work once you start? Photo shooting sounds like the essence of detail and distraction to me if you are up to it.

I hope it will feel like that; it always has before. I am going to *try* to limit my sittings this fall because of my depression. I would rather do that than go in the hospital. I don't see any benefit in being in the hospital now, aside from keeping me alive, which I'd rather do outside the hospital.
>
> > > > Too late, I already took a split pill. It’s not time release so I can’t imagine why there would be a problem.
>
> Wow, you are moving fast. I need to increase my dose of Nardil (still 15 mg) but am a bit anxious about doing it. Do you remember if you had any anxiety when you were beginning Nardil?

I'm going fast, because I've been there before without any startup problems. I'd be going much faster if I wasn't taking wellbutrin still.
I don't recall having any side effects when I started, but it was so long ago. I was just aware of waiting for it to kick in , and waiting and waiting, feeling very depresssed and then it really did kick in. I went with some friends to the beach (just for the day) right after it kicked in and I remember that I couldn't stop talking. I talked the entire day without shutting up. That's why I am suspicious of this new trend of labeling people bipolar II based on drug induced hypermania. Because it was a temporary thing for me, but the antidepressant events went on for years.

> > So day three, any more news? When are you going to raise your dose and do you have any idea of how high you are intending to go? I started on 45mg (well, within one week, if I remember right), but generally through the years I have kept my dose at 30mg because of sleep disturbances which were minimal at 30mg.
> I'll probably go to 1 1/2 pills today this is how sure I am that my pharmacist was not right). I probably won't get to a very high dose. I'd be surprised if I go over 30 mg.

Well, as I said, I did consistently okay on 30mg, but I never felt totally without depression in my life. But I had a lot of stuff to work out. This feels much more biochemical, and that's how my pdoc refers to it.

> I also had very strange and scarey experiences not adjusting to natural light changes (especially from inside to outdoor sunlight) when I had been on 45mg for about six months.
> Wellbutrin caused me to have visual trails and made lights dance--especially coming from a dark space (movie theatre or waking up) to a light space (movie theatre restroom).

This was very very scary because I would "white" out. I became literally blinded by light and it became dangerous because at one point I couldn't figure out where the sidewalk connected to the street, and I had to get some workmen to help me across the street into a building. I'm sure they thought I was drunk. I am sensitive to light, but not literally blinded by it. Coming off the beach, out of the bright light and reflection, same experience. When I went back to 30mg and 45mg premenstrually it never happened again.

>
> You know I like being alone. And I have been so busy--I'm painting the house and so forth. Also when I drive the kids, the other parents pull me aside and talk to me. They like me :-)
:-)
So I'm actually a bit more social than usual.

Yes, being a parent does have some social advantages like that, connections. Because I work with kids all the time and find them interesting, I talk easily to parents about their kids. Some confide a lot to me. It's nice; many times I get to follow kids through different ages.

I am rethinking lamictal, since it was of such benefit to me as an adjunct. Rethinking that perhaps there is a safe way to prevent all the fluid retention it caused me. I know it’s not as simple as taking diuretics, because I already tried that, but I have copied some info off the board which may be useful.

Shelli


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