Psycho-Babble Medication Thread 611

Shown: posts 1 to 25 of 77. This is the beginning of the thread.

 

amineptine/tianeptine for depression

Posted by ian on September 12, 1998, at 11:59:46

Has anyone had experience with either of these European antidepressants

Amineptine (Survector) is basically a dopamine reuptake inhibitor. It's banned from the Olympics, apparently because of its energy boosting capacity.

Tianeptine (Stablon), believe it or not, is a serotonin reuptake accelerator; i.e., it works exactly opposite of Prozac, Zoloft, Paxit and the other SSRIs. Where they keep as much serotonin as possible in circulation, tianeptine takes as much of it as possible out of circlation. Yet it still works and, I would presume, without many of the SSRI side effects.

 

Re: amineptine/tianeptine for depression

Posted by George on September 22, 1998, at 14:03:25

In reply to amineptine/tianeptine for depression, posted by ian on September 12, 1998, at 11:59:46

> Has anyone had experience with either of these European antidepressants

> Amineptine (Survector) is basically a dopamine reuptake inhibitor. It's banned from the Olympics, apparently because of its energy boosting capacity.

> Tianeptine (Stablon), believe it or not, is a serotonin reuptake accelerator; i.e., it works exactly opposite of Prozac, Zoloft, Paxit and the other SSRIs. Where they keep as much serotonin as possible in circulation, tianeptine takes as much of it as possible out of circlation. Yet it still works and, I would presume, without many of the SSRI side effects.
I've tried amineptine, had headaches and severe drousiness, I suspect this is not typical as amineptine is supposed to be very activating.

 

Re: amineptine/tianeptine for depression

Posted by Dr.med. U. Rendenbach on November 28, 1999, at 4:49:48

In reply to amineptine/tianeptine for depression, posted by ian on September 12, 1998, at 11:59:46

> Has anyone had experience with either of these European antidepressants

Has anyone an Idee, how I can buy Survector? The International Pharmacy in Germany is not abel to get it!! Thanks a lot!! Rendenbach, Germany
> Tianeptine (Stablon), believe it or not, is a serotonin reuptake accelerator; i.e., it works exactly opposite of Prozac, Zoloft, Paxit and the other SSRIs. Where they keep as much serotonin as possible in circulation, tianeptine takes as much of it as possible out of circlation. Yet it still works and, I would presume, without many of the SSRI side effects.

 

Re: amineptine/tianeptine for depression

Posted by andrewb on November 28, 1999, at 11:57:35

In reply to Re: amineptine/tianeptine for depression, posted by Dr.med. U. Rendenbach on November 28, 1999, at 4:49:48

Amineptine (Survector) may be ordered from IAS. See their website: www.antiaging-systems.com
No prescription required. Be aware of amineptine's serious abuse potential.

 

Re: amineptine/tianeptine for depression

Posted by Scott L. Schofield on December 8, 1999, at 9:42:45

In reply to Re: amineptine/tianeptine for depression, posted by andrewb on November 28, 1999, at 11:57:35

> Amineptine (Survector) may be ordered from IAS. See their website: www.antiaging-systems.com
> No prescription required. Be aware of amineptine's serious abuse potential.

Do you know if amineptine is to be discontinued in France?

Thanks.

- Scott

 

Re: amineptine no longer available

Posted by jamie on December 9, 1999, at 3:08:37

In reply to Re: amineptine/tianeptine for depression, posted by andrewb on November 28, 1999, at 11:57:35

> Amineptine (Survector) may be ordered from IAS. See their website: www.antiaging-systems.com
> No prescription required. Be aware of amineptine's serious abuse potential.

Amineptine is no longer available at IAS or anywhere else I know of. I think the manufacturer stopped making it for some reason.

 

Re: amineptine no longer available

Posted by Anna P. on December 10, 1999, at 10:04:02

In reply to Re: amineptine no longer available, posted by jamie on December 9, 1999, at 3:08:37

> > Amineptine (Survector) may be ordered from IAS. See their website: www.antiaging-systems.com
> > No prescription required. Be aware of amineptine's serious abuse potential.
>
> Amineptine is no longer available at IAS or anywhere else I know of. I think the manufacturer stopped making it for some reason.

Does it mean it's no longer available in Europe?
Anyway, I was wondering how it can be helpful for
depression with the tendency toward OCD and phobia? I know that it works by taking the serotonin out of the system.

Anna P.

 

Re: amineptine no longer available

Posted by Bruce on December 10, 1999, at 10:47:07

In reply to Re: amineptine no longer available, posted by Anna P. on December 10, 1999, at 10:04:02

> > > Amineptine (Survector) may be ordered from IAS. See their website: www.antiaging-systems.com
> > > No prescription required. Be aware of amineptine's serious abuse potential.
> >
> > Amineptine is no longer available at IAS or anywhere else I know of. I think the manufacturer stopped making it for some reason.
>
> Does it mean it's no longer available in Europe?
> Anyway, I was wondering how it can be helpful for
> depression with the tendency toward OCD and phobia? I know that it works by taking the serotonin out of the system.
>
> Anna P.

Amineptine has too much abuse potential for most governments. I think IAS got theirs from Thailand (!) and maybe the Thai gov't just said no.

Amineptine potentiates dopamine. Anna may be thinking of a related drug, tianeptine, which actually *reduces* the inter-cellular concentrations of serotonin. It's the exact opposite strategy of an SSRI - yet it seems to work (in about 70% of patients, just like every other drug out there). It shows how far we have to go towards understanding just what is going on in depression.

 

Re: amineptine/tianeptine for depression

Posted by gladi van snead on December 11, 1999, at 11:08:30

In reply to Re: amineptine/tianeptine for depression, posted by Dr.med. U. Rendenbach on November 28, 1999, at 4:49:48

What is meant by the "serious abuse potential" of amineptine? Is it addictive? If so, physically or psychologically or both? What happens if the drug is suddenly withdrawn?

If amineptine is unavailable or unreasonably dangerous, is tianeptine available anywhere, under any name? Please reply to psychobabble!


> Has anyone had experience with either of these European antidepressants
>
> Has anyone an Idee, how I can buy Survector? The International Pharmacy in Germany is not abel to get it!! Thanks a lot!! Rendenbach, Germany
> > Tianeptine (Stablon), believe it or not, is a serotonin reuptake accelerator; i.e., it works exactly opposite of Prozac, Zoloft, Paxit and the other SSRIs. Where they keep as much serotonin as possible in circulation, tianeptine takes as much of it as possible out of circlation. Yet it still works and, I would presume, without many of the SSRI side effects.

 

Re: amineptine/tianeptine for depression

Posted by andrewb on December 11, 1999, at 20:29:31

In reply to Re: amineptine/tianeptine for depression, posted by gladi van snead on December 11, 1999, at 11:08:30

> What is meant by the "serious abuse potential" of amineptine? Is it addictive? If so, physically or psychologically or both? What happens if the drug is suddenly withdrawn?
>
> If amineptine is unavailable or unreasonably dangerous, is tianeptine available anywhere, under any name? Please reply to psychobabble!
>
Amineptine use at normal dosages can be stopped suddenly without problems.
Serious amineptine abuse is the use of massive amounts of amineptine (i.e. 1500 mgs./day, just 200mgs. is the max. recommended dose) over a period of months. It may be snorted. It may be used concurrently with speed.
The result of abuse, as I understand it, is large erupting pustules on the body (of unmetabolized amineptine?) and possible liver failure.

 

Re: amineptine no longer available

Posted by Scott L. Schofield on December 12, 1999, at 11:43:51

In reply to Re: amineptine no longer available, posted by Bruce on December 10, 1999, at 10:47:07

> > > Amineptine is no longer available at IAS or anywhere else I know of. I think the manufacturer stopped making it for some reason.

> > Does it mean it's no longer available in Europe? Anyway, I was wondering how it can be helpful for depression with the tendency toward OCD and phobia? I know that it works by taking the serotonin out of the system.

> Amineptine has too much abuse potential for most governments. I think IAS got theirs from Thailand (!) and maybe the Thai gov't just said no.

What about all the new benzodiazepines? It seems silly to allow these drugs to be marketed when others of potentially great benefit for other indications are denied approval because of far less abuse potential.

Why is Wellbutrin (bupropion) not available in the U.K. or Canada?

> Amineptine potentiates dopamine. Anna may be thinking of a related drug, tianeptine, which actually *reduces* the inter-cellular concentrations of serotonin. It's the exact opposite strategy of an SSRI - yet it seems to work (in about 70% of patients, just like every other drug out there). It shows how far we have to go towards understanding just what is going on in depression.

Sometime it seems as if pushing the system in one direction or the other forces a "reset" of the "thermostats".


- Scott

 

Re: amineptine no longer available

Posted by Justin on January 7, 2000, at 13:38:08

In reply to Re: amineptine no longer available, posted by Scott L. Schofield on December 12, 1999, at 11:43:51

> > > > Amineptine is no longer available at IAS or anywhere else I know of. I think the manufacturer stopped making it for some reason.
>
> > > Does it mean it's no longer available in Europe? Anyway, I was wondering how it can be helpful for depression with the tendency toward OCD and phobia? I know that it works by taking the serotonin out of the system.
>
> > Amineptine has too much abuse potential for most governments. I think IAS got theirs from Thailand (!) and maybe the Thai gov't just said no.
>
> What about all the new benzodiazepines? It seems silly to allow these drugs to be marketed when others of potentially great benefit for other indications are denied approval because of far less abuse potential.
>
> Why is Wellbutrin (bupropion) not available in the U.K. or Canada?
>
> > Amineptine potentiates dopamine. Anna may be thinking of a related drug, tianeptine, which actually *reduces* the inter-cellular concentrations of serotonin. It's the exact opposite strategy of an SSRI - yet it seems to work (in about 70% of patients, just like every other drug out there). It shows how far we have to go towards understanding just what is going on in depression.
>
> Sometime it seems as if pushing the system in one direction or the other forces a "reset" of the "thermostats".
>
>
> - ScottI

 

Re: amineptine no longer available I have known a

Posted by Justin on January 7, 2000, at 13:39:08

In reply to Re: amineptine no longer available, posted by Scott L. Schofield on December 12, 1999, at 11:43:51

> > > > Amineptine is no longer available at IAS or anywhere else I know of. I think the manufacturer stopped making it for some reason.
>
> > > Does it mean it's no longer available in Europe? Anyway, I was wondering how it can be helpful for depression with the tendency toward OCD and phobia? I know that it works by taking the serotonin out of the system.
>
> > Amineptine has too much abuse potential for most governments. I think IAS got theirs from Thailand (!) and maybe the Thai gov't just said no.
>
> What about all the new benzodiazepines? It seems silly to allow these drugs to be marketed when others of potentially great benefit for other indications are denied approval because of far less abuse potential.
>
> Why is Wellbutrin (bupropion) not available in the U.K. or Canada?
>
> > Amineptine potentiates dopamine. Anna may be thinking of a related drug, tianeptine, which actually *reduces* the inter-cellular concentrations of serotonin. It's the exact opposite strategy of an SSRI - yet it seems to work (in about 70% of patients, just like every other drug out there). It shows how far we have to go towards understanding just what is going on in depression.
>
> Sometime it seems as if pushing the system in one direction or the other forces a "reset" of the "thermostats".
>
>
> - ScottI

 

Re: amineptine no longer available I have known a

Posted by Justin on January 7, 2000, at 13:47:03

In reply to Re: amineptine no longer available, posted by Scott L. Schofield on December 12, 1999, at 11:43:51

> > > > Amineptine is no longer available at IAS or anywhere else I know of. I think the manufacturer stopped making it for some reason.
>
> > > Does it mean it's no longer available in Europe? Anyway, I was wondering how it can be helpful for depression with the tendency toward OCD and phobia? I know that it works by taking the serotonin out of the system.
>
> > Amineptine has too much abuse potential for most governments. I think IAS got theirs from Thailand (!) and maybe the Thai gov't just said no.
>
> What about all the new benzodiazepines? It seems silly to allow these drugs to be marketed when others of potentially great benefit for other indications are denied approval because of far less abuse potential.
>
> Why is Wellbutrin (bupropion) not available in the U.K. or Canada?
>
> > Amineptine potentiates dopamine. Anna may be thinking of a related drug, tianeptine, which actually *reduces* the inter-cellular concentrations of serotonin. It's the exact opposite strategy of an SSRI - yet it seems to work (in about 70% of patients, just like every other drug out there). It shows how far we have to go towards understanding just what is going on in depression.
>
> Sometime it seems as if pushing the system in one direction or the other forces a "reset" of the "thermostats".
>
>
> - Scott

I have known about amineptine and taken it for a number of years. I used to purchase it in either Greece or Spain. Suddenly some people apparently started taking large doses for stimulant effects and that, in turn, led to removal of licenses to sell (I suspect everywhere from what I can tell because I have been investigating and everyone seems to have stopped offering it. ) Rational appears to be the usual drug-panic thinking, along with fear that anything that makes you feel ok or good must be bad -- can't imagine why the fact that a few people were taking 1500 mg (normal dose is 200 mg per day) should lead to this turn of events considering how promising the medication was in so many areas. Never once found it addicting and had no withdrawal problems whatsoever. Sick thinking of the times! Justin.

 

Re: amineptine no longer available. to Scott

Posted by Cathy on January 8, 2000, at 13:02:29

In reply to Re: amineptine no longer available, posted by Scott L. Schofield on December 12, 1999, at 11:43:51

Hi Scott, I'm on Wellbutrin and I live in Canada. The doctors here just started using it at the beginning of this year.

 

Re: amineptine no longer available. to Scott

Posted by Scott L. Schofield on January 8, 2000, at 16:04:21

In reply to Re: amineptine no longer available. to Scott, posted by Cathy on January 8, 2000, at 13:02:29

> Hi Scott, I'm on Wellbutrin and I live in Canada. The doctors here just started using it at the beginning of this year.

Yay!


- Scott

 

Re: amineptine no longer available I have known a

Posted by Scott L. Schofield on January 8, 2000, at 16:19:29

In reply to Re: amineptine no longer available I have known a, posted by Justin on January 7, 2000, at 13:47:03

> > > > > Amineptine is no longer available at IAS or anywhere else I know of. I think the manufacturer stopped making it for some reason.

> > > Amineptine has too much abuse potential for most governments. I think IAS got theirs from Thailand (!) and maybe the Thai gov't just said no.

> > What about all the new benzodiazepines? It seems silly to allow these drugs to be marketed when others of potentially great benefit for other indications are denied approval because of far less abuse potential.

> I have known about amineptine and taken it for a number of years. I used to purchase it in either Greece or Spain. Suddenly some people apparently started taking large doses for stimulant effects and that, in turn, led to removal of licenses to sell (I suspect everywhere from what I can tell because I have been investigating and everyone seems to have stopped offering it. ) Rational appears to be the usual drug-panic thinking, along with fear that anything that makes you feel ok or good must be bad -- can't imagine why the fact that a few people were taking 1500 mg (normal dose is 200 mg per day) should lead to this turn of events considering how promising the medication was in so many areas. Never once found it addicting and had no withdrawal problems whatsoever. Sick thinking of the times! Justin.

Agreed.


Dear Justin,

Would you mind answering a few questions?

1. What is your diagnoses and how would you characterize your depression, assuming you suffer from it?
2. In what ways do you feel that amineptine helped you?
3. What dosages did you take?
4. What side-effects if any did you experience?
5. Was it combined with any other drugs?
6. Why did you stop taking it?
7. How are you doing? Well, I hope. :)


Much Thanks.


- Scott

 

Re: amineptine/tianeptine for depression

Posted by mocdoc on June 5, 2001, at 17:12:33

In reply to Re: amineptine/tianeptine for depression, posted by andrewb on December 11, 1999, at 20:29:31

Has anyone tried it?
Good Health!
mocdoc

 

Re: amineptine/tianeptine for depression

Posted by Anna P. on June 6, 2001, at 14:54:09

In reply to Re: amineptine/tianeptine for depression, posted by mocdoc on June 5, 2001, at 17:12:33

Yes, it's a very effective AD with no weight gain, and sexual dysfunction, energizing.
What to wish for more?

Anna P.

 

Re: amineptine/tianeptine for depression

Posted by mocdoc on June 6, 2001, at 15:07:42

In reply to Re: amineptine/tianeptine for depression, posted by Anna P. on June 6, 2001, at 14:54:09

Dear Anna-where did you buy tianeptine? And what dose do you use-I gather it might be 12.5 mg thrice daily. Any side effects? How long have you been taking it? And what's your diagnosis-mine's Bipolar II with accompanying OCD.
Glad for you,
mocdoc

 

Re: HAS ANYONE TRIED TIANEPTINE??

Posted by jodsteroo on June 6, 2001, at 15:34:35

In reply to Re: amineptine/tianeptine for depression, posted by mocdoc on June 5, 2001, at 17:12:33

has anyone tried tianeptine?? im very curious....if so what were the side effects if any?what dose sis you try? and how many times a day did you have to take it?thanks...jodi

 

Re: amineptine/tianeptine for depression

Posted by Anna P. on June 6, 2001, at 16:37:04

In reply to Re: amineptine/tianeptine for depression, posted by mocdoc on June 6, 2001, at 15:07:42

> Dear Anna-where did you buy tianeptine? And what dose do you use-I gather it might be 12.5 mg thrice daily. Any side effects? How long have you been taking it? And what's your diagnosis-mine's Bipolar II with accompanying OCD.
> Glad for you,
> mocdoc

Hi Mocdoc,

Tianeptine may be purchased at antiaging systems.
There is no side effects exept the transient anxiety that can be resolved by taking
Lorazepam. I'm treatment resistant BipolarII, so later on I had to augment Tianeptine either with Lithium or Topamax.

Good luck,

Anna P.

 

Re: HAS ANYONE TRIED TIANEPTINE??

Posted by mocdoc on June 6, 2001, at 16:40:19

In reply to Re: HAS ANYONE TRIED TIANEPTINE??, posted by jodsteroo on June 6, 2001, at 15:34:35

Dear Jodi,
Many studies have been done in France and it appears to be the equal of any other antidepressant though not superior. My personal interest in the drug is that all SSRI's make me worse, not better so it would seem logical to try a reuptake enhancer instead of a reuptake inhibitor. If you put "tianeptine" into your search engine, e.g. Google or I'm sure any other search engine, you'll find a number of studies. If that's not possible for you, post another message on this board and I'll post the URLs for a few studies.
Good luck,
mocdoc

 

Re: question for mocdoc?

Posted by jodsteroo on June 6, 2001, at 20:08:59

In reply to Re: HAS ANYONE TRIED TIANEPTINE??, posted by mocdoc on June 6, 2001, at 16:40:19

> Dear Jodi,
> Many studies have been done in France and it appears to be the equal of any other antidepressant though not superior. My personal interest in the drug is that all SSRI's make me worse, not better so it would seem logical to try a reuptake enhancer instead of a reuptake inhibitor. If you put "tianeptine" into your search engine, e.g. Google or I'm sure any other search engine, you'll find a number of studies. If that's not possible for you, post another message on this board and I'll post the URLs for a few studies.
> Good luck,
> mocdoc

the ssri's make me worse too, i feel horrible on them, headaches, fatigue, insomnia, increaced anxiety and depression. i have researched tieneptine alot over the internet and have considered ordering it. i have yet to come across someone who has actuelly used it here in the u.s. and was very curious to hear someones experiences with it first hand. anyway my question to you is, if you feel worse on the ssri's like i do, have you found anything that you do feel better on? do you suffer from just depression? i have tried everything for my depression and anxiety , from e.c.t. to reboxetine to all the meds here in the u.s. rx'ed for depression,anxiety,bipolar,add,sleep probs..ect. and nothings really helped much. im just curious if anyone else has any suggestions!
thanks...jodi!

 

Re: question for mocdoc?

Posted by mocdoc on June 6, 2001, at 21:10:33

In reply to Re: question for mocdoc?, posted by jodsteroo on June 6, 2001, at 20:08:59

Dear Jodi,
I have rapidly cycling Bipolar II as well as OCD. The old tricyclics and the newer SSRIs particularly (and paradoxically) make my OCD worse,as well as causing anxiety.None have helped my depression which often clears when not on antidepressants.I also have light and colour sensitivity, and smell and occasionally taste hallucinations, i.e. I smell and taste things that just aren't there. These latter symptoms may represent some temporal lobe brain dysfunction. My doctor is now trying gradually increasing doses of the antiepileptic Neurontin added to a low dose of clonezepam which I have been taking for two years. Its too early to know for sure but it seems to have helped the light sensitivity. High doses of Neurontin occasionally help OCD so I'm hopeful. Other antiepileptics like Lamictal, Depacote and Tegretol have been of no help. Nor has lithium. I have had no experience with tianeptine but perhaps I'll try it if the present plan fails.
Don't give up-there's lots of drugs out there to try as well as cognitive therapy, prayer, Yoga, meditation, etc., etc.
Be well. And If you can't -fake it- and soon the fakery will become your new reality! That's what my cognitive therapist taught me.
mocdoc


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