Psycho-Babble Medication Thread 14211

Shown: posts 1 to 4 of 4. This is the beginning of the thread.

 

Hormones & mood interaction with age & cycles (Q)

Posted by TJ on October 29, 1999, at 22:26:42

I am regularly impressed by anecdotal statements that
relate hormonal events such as puberty, pregnancy, and
menopause (many others possible) to dramatic changes in
mood and outlook.

Question: Where is the medical research to relate
brain chemistry changes with changes in hormone levels
and ratios? Why is the focus on SSRI's and CNS's?

$?

My observations, both direct and indirect lead me to think that hormones
should be the first thing tinkered with, not the last. The
chemical pathways are shared with the dopamine/serotonin affecting
drugs. Think testosterone, estrogen, progesterone, oxytocin, phenylethylanline,
and perhaps DHEA.

Do boys who "outgrow" ADHD, do so because they have big new resevoirs of
testosterone? Do girls not show the H of ADHD because they have so little
testosterone relatively speaking? Do women whose depression lifts completely
while pregnant lack adequate estrogen the rest of the time?

Conversely, is it not to be expected that messing with serotonin pathways
will lead to changes in chemical feedback loops that govern sexual response?

So, what is the hormone story, and why not work from that end?

TJ

 

Re: Hormones & mood interaction with age & cycles (Q)

Posted by Noa on October 30, 1999, at 1:46:09

In reply to Hormones & mood interaction with age & cycles (Q) , posted by TJ on October 29, 1999, at 22:26:42

I just saw an ad in the Washington Post that NIMH is doing a study on PMS and depression. You have to not be on any meds to get into the study, but maybe this is of interest to you.

 

Re: Hormones & mood interaction with age & cycles (Q)

Posted by jamie on October 30, 1999, at 3:53:37

In reply to Hormones & mood interaction with age & cycles (Q) , posted by TJ on October 29, 1999, at 22:26:42


> So, what is the hormone story, and why not work from that end?
>
> TJ

I think hormone therapy does help some people. But excess hormones just as bad as low. And even downright dangerous. Supplementing hormones to a normal hormone level impacts a lot more than the brain. The science of ADs is not well understood. The science of hormones even less. I think a blood test to check hormone levels prior to supplementation would be very prudent. If a hormone is in an abnormal range then treat it. Whether it helps mood would remain to be seen on a case by case basis.

 

Hormones & weight loss

Posted by dove on October 30, 1999, at 10:02:44

In reply to Hormones & mood interaction with age & cycles (Q) , posted by TJ on October 29, 1999, at 22:26:42

Just glanced at Medscape and saw the new numbers for the hormone Leptin trial for obesity.

"Treatment with the hormone leptin increases the rate of average weight loss for both lean and obese adults, according to an article in the October 27 issue of The Journal of the American Medical Association (JAMA), a theme issue on obesity."

here's the link:
http://pharmacotherapy.medscape.com/MedscapeWire/1999/10.99/medwire.1026.treatment.html

dove


This is the end of the thread.


Show another thread

URL of post in thread:


Psycho-Babble Medication | Extras | FAQ


[dr. bob] Dr. Bob is Robert Hsiung, MD, bob@dr-bob.org

Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.