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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by saintjames on April 19, 1999, at 17:23:14
There are 2 ez things you can do if pills and capsules irritate your GI tract. Pills are the worst here because they just sit on the lining and slowly desolve, releasing a high concentration in a small area. Try eating something 30 mins b4 you take your pills to act as a buffer. Some meds are not to be taken with food, so check with you Rx. Generally the w/o food is a bio availability issue, so if the pills cause you upset you can still take them with food.
Even better try taking meds in liquid form. Some meds come in liquid form...you can also make your own, too. Liquids pass thru a membrane better....it is the ideal form to take meds in because you will get the highest concentration into your body with less or no upset. Timed released meds need to stay in a solid form but other meds are worth checking with the RX to see if you can mix them with a liquid (The Rx can sugest
liquid to use,avoid OJ). Some things taste nasty (like Doxipin) but I know Prozac works OK.
I've just changed Rx's and am going to see if they are a compounding Rx, so they could prepare this for me. There are some shelf life issues when you convert a med to liquid so "at home" you don't want to prepare more than 1 dose at a time.
Again you want to run all this by the Rx before proceding.
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Posted by paul on April 21, 1999, at 9:14:48
In reply to GI irritation and how to get more out of you meds, posted by saintjames on April 19, 1999, at 17:23:14
Do you happen to know if sustained-release formulations, i.e. Wellbutrin SR, are dissolved slowly because of the outer layer, or because of the binding of all of the ingredients in such a way as to release the active ingredients slowly even if the tablet has been broken in half?
In other words, if I broke a Wellbutrin SR (150 mg) in half, would one half be "immediate-release" 75 mg?
Thanks.
Posted by anne on April 22, 1999, at 21:13:23
In reply to in this connection....., posted by paul on April 21, 1999, at 9:14:48
I took Sinemet CR for a while - they were a hard extended release tablet which the neurologist told me was fine to break in half as the whole tablet is slow to dissolve, not just the outer coating. Call your pharmacy and ask for sure. If it has a shiny hard coating that is a different color from the inside I would be more wary of breaking it.
This is the end of the thread.
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