Psycho-Babble Medication Thread 1287

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Prozac and 5-hydroxytryptophan

Posted by Karen on November 17, 1998, at 19:15:54

Does anyone know if you can safely combine Prozac with a supplement of hydroxytryptophan? My client had been on Prozac 80 mg daily in the AM and trazodone 150 mg at night. Client stopped trazodone....slowly weaned off due to excessive nightmares which we thought perhaps being caused by trazodone...has been on both meds approx 10 years give or take. Without the trazodone client sleeps 2-3 hours per night and then unable to go back to sleep. Client is becoming extremely exhausted/fatigued. Takes 50-100 mg trazodone occasionally to get some sleep. has been off trazodone for 4-6 weeks now. Client said years ago the only thing that helped was taking tryptophan but then could not find it anymore. Client is afraid to come completely off Prozac so wishes to simply add 100 mg 5-Hydroxytryptophan at bedtime. Anyone tried this or know if this combination is safe? Thanks so much!!

 

Re: Prozac and 5-hydroxytryptophan

Posted by Toby on November 18, 1998, at 9:59:22

In reply to Prozac and 5-hydroxytryptophan, posted by Karen on November 17, 1998, at 19:15:54

There is a theoretical risk of the serotonin syndrome when combining 5HT with an SSRI. However, I can't find any report of that actually happening. 5HT is stonger than tryptophan and therefor may work better.


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