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Dr. Bob is Robert Hsiung, MD,
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Posted by kka on November 11, 2003, at 11:55:37
In reply to Re: Topamax Experiences?kka, posted by msmelissa on November 11, 2003, at 10:32:33
Please, please, please, keep me posted I have yet to find any info on Topamax and Depakote , my husband is on both as well as Paxil. Thanks for the reply. Take care!
I guess that I will be staying on the depakote...the dr. didn't say otherwise. I've wondered about it myself. They are both anticonvulsants????
Posted by TexasChic on November 11, 2003, at 12:24:22
In reply to Dumb Question about Topomax, posted by headachequeen on November 11, 2003, at 10:48:20
> does the weight loss factor in Topomax know when to quit?Nobody's laughing. Its not funny that the medication you have to take for your epilepsy is causing this unwanted side effect. And I don't blame you for not wanting to tell your coworkers. Its none of their business and is only something you should share with someone when you're ready to. Unfortunately I don't have the answers for you. All I know is that it's a medication that is prescribed to some to help lose weight because of the way it suppresses your appetite. Have you shared your fear that you may never regain your appetite on the Topamax with your doctor? If he isn't concerned with this, I would be concerned about him! You obviously can't just waste away into nothing. Please talk to your doc soon, and I will try to take my own advice and talk to mine about my concerns as well. Good luck!
Posted by msmelissa on November 11, 2003, at 12:34:06
In reply to Topamax Experiences?, posted by Kingfish on January 4, 2001, at 7:29:48
Will do... and please do the same for me.
Thank you
Posted by Murphia on November 11, 2003, at 12:37:02
In reply to Re: Cutting Your Pills in Half- esp. extended release » Nissy, posted by chicago77 on October 27, 2003, at 9:01:38
Topamax (topiramate) does not come in extended release. Sprinkles caps are to take apart and sprinkle on food if you desire. You can also swallow them as a capsule.
> > What about seeing the little white balls that are inside the capsule in your stool? I am on effexor XR and I see those white balls all the time. Does this mean my body isn't metabolizing them or absorbing the medication? Do you know anything about this?
>
> Nissy,
> I fact I do know about this. This is what I believe is called "sprinkles." There are quite a few meds that are capsules with "balls" inside. You will notice that these are all extended release formulations. This works the same way in that your body first processes the cap to release the sprinkles, then the "balls" are metabolized similarly to a controlled release tab. So, yes, you're body is using the drug and, no, it's no reason for concern. Talk to your doc if it really bothers/worries you.
> I do believe that this is one of the exceptions about breaking open capsules. The gelatin capsule dissolves pretty rapidly and the sprinkles are released and go to work. On the other hand, capsules with powder are meant to be taken whole b/c the powder would start to absorb in your mouth, esophagus, etc... before it gets to your stomach. You may want to double check this with a pharmacist. From what I remember, "sprinkle" caps can be opened and (go figure) "sprinkled" over food or mixed in with something like apple sauce for those that may not be able to take it whole (esp. children and the elderly). Hope this was helpful, but remember that I am not an expert on this just b/c I have some experience with it. Be sure to follow your health care provider's instructions and any information provided with your Rx. And ASK as many questions as you want!! This is your health!!
> Side note: I am working on my Master's degree to become a Physician Assistant. This is why you will often see me refer to a "health care provider" rather than your "doc." Keep in mind too that PAs are specifically trained to provide patient information and education, and we tend to spend quite a bit more time with patients until all questions are resolved. If there is a PA in the office/clinic that you go to, don't be afraid to talk to them seperately if you feel that your doc isn't "getting the job done." I give a 99% guarantee that you will be very happy with their service and caring!!
Posted by Murphia on November 11, 2003, at 12:46:55
In reply to re: the benefits of topamax, posted by TexasChic on November 10, 2003, at 15:40:08
I am a researcher and have been researching topamax for about 6-7 years. Topamax interferes with estrogen-type birth control. So I would back it up with condom usage, or stronger BC. Also, depression is side effect of topamax. Topamax works on the gaba receptors in the temporal lobe. Great for mania side of bipolar, but does nothing, if not exacerbate depression and anxiety. An anti-depressant is the usual protocol add-on for topamax. Or another MS which works on depression, such as lamicatal. Regards. Murph.
> Hi, this is my first post, but I've been lurking for a while. My doc currently has me on 75mg Topamax for: compulsive eating, as a mood stabilizer, and for some OCD tendencies; and 20mg Lexapro for depression and anxiety. I have a side effect from the Topamax I haven't heard anyone else mention. I began getting a feeling about it, and then I read in the accompanying literature that it can interfere with birth control pills. Anything else that does this (like antibiotics) messes up my whole cycle (sorry guys) causing much pain and a worse than ever wave of depression (this is because of female problems I've had since I was young). I was just wondering if anyone else has had this interruption in their BCP's and if stronger one's may be the answer. I was also wondering if anyone even knew about it since my doc didn't tell me!
> I have also been experiencing extreme anxiety, and mounting depression ever since I've started my new regimen a month ago. I've been on the SSRI merry-go-round before, so I know it takes time, and things have been extremely crappy in my life lately, so I can't blame it all on the meds. I've definitely been through some rougher spells in the last few months than I have in years, which was why I changed my meds in the first place. But its gets really hard to tell sometimes if the pills are working like they're supposed to, or if you've waited long enough and its time to give up and try something else. I hate this wait and see part of it. Anyway, this is kind of half 'Psycho-Babble' and half 'Psychological Babble', so I didn't know where to put it. Hope it wasn't too long.
Posted by kka on November 11, 2003, at 13:09:12
In reply to re: the benefits of topamax, posted by Murphia on November 11, 2003, at 12:46:55
Murph,
Is Johnson and Johnson really reformulating the drug, if so how far along are they? Have you found any weight loss at 100mgs. Is is safer to increase past 100mgs for weight loss reasons alone? How about long term use?I am hoping Topamax is the drug for me. I am begining to think I really have mild ocd along with binge or over-eating to cover emotions. I keep getting diagnosed for depression/anxiety but I feel the extra 20 lbs is really the cause of the depression. I am currently on Effexor 75 mgs, 150 wellbutrin and have reached 75 mg of Topamax after almost four weeks, without any real side effects. I figured I would stop at 100?? I am really tired all the time with no real motivation which has been the case for about six months now (before Topmax) Would increasing the dose help with energy or would it be more sedating? Overall I am jittery-but tired sometimes hungry sometimes not as hungry but never not been able to eat something
I am also curious about your thoughts on time of day dosing, I take the full dose at night, but I see some people split their doese and take on during the day.
Sorry to be so full of questions, I was excited to get someone with your background on the board. My doctor feels like it is still "experimental" so he is hardly a resource.I know you are probably still busy researching, whatever your personal thoughts or theories I would love to hear about them, if you have time.
Thanks,
Kristen
> I am a researcher and have been researching topamax for about 6-7 years. Topamax interferes with estrogen-type birth control. So I would back it up with condom usage, or stronger BC. Also, depression is side effect of topamax. Topamax works on the gaba receptors in the temporal lobe. Great for mania side of bipolar, but does nothing, if not exacerbate depression and anxiety. An anti-depressant is the usual protocol add-on for topamax. Or another MS which works on depression, such as lamicatal. Regards. Murph.
>
>
> > Hi, this is my first post, but I've been lurking for a while. My doc currently has me on 75mg Topamax for: compulsive eating, as a mood stabilizer, and for some OCD tendencies; and 20mg Lexapro for depression and anxiety. I have a side effect from the Topamax I haven't heard anyone else mention. I began getting a feeling about it, and then I read in the accompanying literature that it can interfere with birth control pills. Anything else that does this (like antibiotics) messes up my whole cycle (sorry guys) causing much pain and a worse than ever wave of depression (this is because of female problems I've had since I was young). I was just wondering if anyone else has had this interruption in their BCP's and if stronger one's may be the answer. I was also wondering if anyone even knew about it since my doc didn't tell me!
> > I have also been experiencing extreme anxiety, and mounting depression ever since I've started my new regimen a month ago. I've been on the SSRI merry-go-round before, so I know it takes time, and things have been extremely crappy in my life lately, so I can't blame it all on the meds. I've definitely been through some rougher spells in the last few months than I have in years, which was why I changed my meds in the first place. But its gets really hard to tell sometimes if the pills are working like they're supposed to, or if you've waited long enough and its time to give up and try something else. I hate this wait and see part of it. Anyway, this is kind of half 'Psycho-Babble' and half 'Psychological Babble', so I didn't know where to put it. Hope it wasn't too long.
>
>
Posted by Murphia on November 11, 2003, at 14:04:32
In reply to re: the benefits of topamax » Murphia, posted by kka on November 11, 2003, at 13:09:12
J&J (Ortho McNeill) says in their press releases they are reformulating a more "user-friendly" topa. That could be - but I would not hold my breath. Ortho had really hoped topa would be their cash cow, but it has failed miserably all the FDA and clinical trials, and now is only approved as an anticonvulsant, with nasty side efffects. Off label use has not shown to be as effective as they hoped it would be due to the s/es. Weight loss is a random side effect, not everyone experiences it, however, it is a nice bonus if it helps your other symptoms.
Max therapeutic dosage of topa is recommended to be 400 mg., but I have talked to people that have been up to 600 mg, so you can go higher. Topa has actually shown to be very effective for binge eating and instrusive thought disorders, so it just may help you. As far as time of day, many people play with splitting their dose, or taking all at night if the s/es for them are bad. Topamax can be very sedating, and once again, that's kind an individual thing. For me it is, so I take mine at night. I have corresponded with a few people that say it makes them jittery, so they take it in the morning. Many people split half and half morning and night. Topa's half life really lends itself more effective at taking twice a day.
Topa doesn't seem to have any adverse effect on long term use, except for maybe hair loss, which becoming quite a frequent complaint. Topa really doesn't do much for depression though, so you want to watch that, and get a stronger AD if warranted.
You also want to keep watch your eyes, kidneys, urinary tract, drink tons of fluids and take a lot of vits, because topa robs your body of a lot of vits. Hope this helps.> Murph,
> Is Johnson and Johnson really reformulating the drug, if so how far along are they? Have you found any weight loss at 100mgs. Is is safer to increase past 100mgs for weight loss reasons alone? How about long term use?
>
> I am hoping Topamax is the drug for me. I am begining to think I really have mild ocd along with binge or over-eating to cover emotions. I keep getting diagnosed for depression/anxiety but I feel the extra 20 lbs is really the cause of the depression. I am currently on Effexor 75 mgs, 150 wellbutrin and have reached 75 mg of Topamax after almost four weeks, without any real side effects. I figured I would stop at 100?? I am really tired all the time with no real motivation which has been the case for about six months now (before Topmax) Would increasing the dose help with energy or would it be more sedating? Overall I am jittery-but tired sometimes hungry sometimes not as hungry but never not been able to eat something
>
> I am also curious about your thoughts on time of day dosing, I take the full dose at night, but I see some people split their doese and take on during the day.
> Sorry to be so full of questions, I was excited to get someone with your background on the board. My doctor feels like it is still "experimental" so he is hardly a resource.
>
> I know you are probably still busy researching, whatever your personal thoughts or theories I would love to hear about them, if you have time.
> Thanks,
> Kristen
>
>
> > I am a researcher and have been researching topamax for about 6-7 years. Topamax interferes with estrogen-type birth control. So I would back it up with condom usage, or stronger BC. Also, depression is side effect of topamax. Topamax works on the gaba receptors in the temporal lobe. Great for mania side of bipolar, but does nothing, if not exacerbate depression and anxiety. An anti-depressant is the usual protocol add-on for topamax. Or another MS which works on depression, such as lamicatal. Regards. Murph.
> >
> >
> > > Hi, this is my first post, but I've been lurking for a while. My doc currently has me on 75mg Topamax for: compulsive eating, as a mood stabilizer, and for some OCD tendencies; and 20mg Lexapro for depression and anxiety. I have a side effect from the Topamax I haven't heard anyone else mention. I began getting a feeling about it, and then I read in the accompanying literature that it can interfere with birth control pills. Anything else that does this (like antibiotics) messes up my whole cycle (sorry guys) causing much pain and a worse than ever wave of depression (this is because of female problems I've had since I was young). I was just wondering if anyone else has had this interruption in their BCP's and if stronger one's may be the answer. I was also wondering if anyone even knew about it since my doc didn't tell me!
> > > I have also been experiencing extreme anxiety, and mounting depression ever since I've started my new regimen a month ago. I've been on the SSRI merry-go-round before, so I know it takes time, and things have been extremely crappy in my life lately, so I can't blame it all on the meds. I've definitely been through some rougher spells in the last few months than I have in years, which was why I changed my meds in the first place. But its gets really hard to tell sometimes if the pills are working like they're supposed to, or if you've waited long enough and its time to give up and try something else. I hate this wait and see part of it. Anyway, this is kind of half 'Psycho-Babble' and half 'Psychological Babble', so I didn't know where to put it. Hope it wasn't too long.
> >
> >
>
>
Posted by TexasChic on November 11, 2003, at 14:07:02
In reply to re: the benefits of topamax, posted by Murphia on November 11, 2003, at 12:46:55
> I am a researcher and have been researching topamax for about 6-7 years. Topamax interferes with estrogen-type birth control. So I would back it up with condom usage, or stronger BC. Also, depression is side effect of topamax. Topamax works on the gaba receptors in the temporal lobe. Great for mania side of bipolar, but does nothing, if not exacerbate depression and anxiety. An anti-depressant is the usual protocol add-on for topamax. Or another MS which works on depression, such as lamicatal. Regards. Murph.
>
> Thank you. That backs up my theory about Topamax diminishing the effectiveness of my birth control to control my monthly cycle pain. I appreciate your help.
Posted by headachequeen on November 11, 2003, at 14:23:14
In reply to Re: Dumb Question about Topomax » headachequeen, posted by kka on November 11, 2003, at 11:49:02
> Headache Queen,
> What kind of work are you doing? Did you weight 200 lbs. How much have you lost in what period of time and what dose of Topamax...sorry for all the questions, just trying to keep up with the thread. Thanksamong the things I do when I am not feeling sorry for myself because I am no longer slim and
young (sigh) is train dogs... I also breed and show dogs... one of the things I have become good at is reprogramming dogs with behaviour problems... probably because of my own personality problems ?? <s>... and one of the tricks I use is challenging them to develop self
esteem by using tunnels and low level agility...
one day I decided that I wanted to get into agility and become an instructor... and then I wanted to teach my dogs to track and have them
certified as real trackers (my breed is not known as tracking or working dogs) not for the
kennel club tracking test... then I wanted them
to become really working qualified... then I wanted the next level...
and now that I have become thin enough to work the courses I want to be able to do real searches with them... right now we are working on low level training and hoping to certify...
I wanted all this but it was still not enough incentive to lose the weight... if it wouldn't come off in a month it was not going to come off and I would quit ... it was my way of telling the world that I was smarter than most people so to heck with it, meet me on my terms I think...
I was 209 pounds when I started the Topomax in mid-January ...
and that is the first time I have admitted it...
when I left for the course I was 145... and don't know where it will stop...
Posted by headachequeen on November 11, 2003, at 14:37:05
In reply to Re: Dumb Question about Topomax, posted by TexasChic on November 11, 2003, at 12:24:22
This brings up another irritation...
my neurologist operates on a three to four month programme: he sees patients and then tells them to return in three or four months...
orders tests and tells the patient to return in three or four months to get the results.
I don't know about the others, but I find this
frustrating and sometimes totally upsetting.
When the tests were ordered to see if I might have MS as well due to a lack of muscle control in my right arm and related to my right eye, he told me to come back in three to four months...
this does not exactly give one a great feeling...
and yet he is the best in our area...
When I decided to do this, my own doctor asked if it were a good idea, given my health situation... I looked at him and asked what health situation? if the neurologist doesn't need to see me for three months, I don't think I need to worry... I just packed my pills and my computer passwords and away I went and frankly I think I am doing a lot of good for me... if I could just get enough sleep...
when I go into town this evening I shall get a multi-vitamin and some vitamin C and E... either that or just start taking the same vitamin cocktail I feed my dogs...
funny: I am so careful about the vitamins I feed to them... never thought of myself...
it takes ages to grind up their vitamins and get them mixed into their meals...
maybe time to pop them into my own meals...
thanks for the idea in the other post...
and I shall ask my own doctor for more information....
meanwhile, this is controlling previous urges to have chocolate bars and eat until I can't move I must admit...
could it be that this lets one level off at one's proper weight??????
Posted by kka on November 11, 2003, at 14:50:05
In reply to re: the benefits of topamax, posted by Murphia on November 11, 2003, at 14:04:32
>
Thanks for being so helpful!!Do you think I could drop (slowly) the Effexor and just take Topamax and wellbutrin? I think the Effexor makes me jittery.
Also my husband has added Topamax to Paxil and 500 mgs of Depakote which is also an anti-conv. Can Topamax and Depakote be taken together if not can Depakote be stopped cold turkey?
For the hair loss on Topamx, what vit. would counteract this.
Just out of curiousity, in the Ortho study, didn't they give the subjects very small does at first and added mgs very slowly? This I have found has completely eliminated the s/e? I can't believe the s/e were so bad to call it off.
Thanks again
J&J (Ortho McNeill) says in their press releases they are reformulating a more "user-friendly" topa. That could be - but I would not hold my breath. Ortho had really hoped topa would be their cash cow, but it has failed miserably all the FDA and clinical trials, and now is only approved as an anticonvulsant, with nasty side efffects. Off label use has not shown to be as effective as they hoped it would be due to the s/es. Weight loss is a random side effect, not everyone experiences it, however, it is a nice bonus if it helps your other symptoms.
>
> Max therapeutic dosage of topa is recommended to be 400 mg., but I have talked to people that have been up to 600 mg, so you can go higher. Topa has actually shown to be very effective for binge eating and instrusive thought disorders, so it just may help you. As far as time of day, many people play with splitting their dose, or taking all at night if the s/es for them are bad. Topamax can be very sedating, and once again, that's kind an individual thing. For me it is, so I take mine at night. I have corresponded with a few people that say it makes them jittery, so they take it in the morning. Many people split half and half morning and night. Topa's half life really lends itself more effective at taking twice a day.
>
> Topa doesn't seem to have any adverse effect on long term use, except for maybe hair loss, which becoming quite a frequent complaint. Topa really doesn't do much for depression though, so you want to watch that, and get a stronger AD if warranted.
> You also want to keep watch your eyes, kidneys, urinary tract, drink tons of fluids and take a lot of vits, because topa robs your body of a lot of vits. Hope this helps.
>
> > Murph,
> > Is Johnson and Johnson really reformulating the drug, if so how far along are they? Have you found any weight loss at 100mgs. Is is safer to increase past 100mgs for weight loss reasons alone? How about long term use?
> >
> > I am hoping Topamax is the drug for me. I am begining to think I really have mild ocd along with binge or over-eating to cover emotions. I keep getting diagnosed for depression/anxiety but I feel the extra 20 lbs is really the cause of the depression. I am currently on Effexor 75 mgs, 150 wellbutrin and have reached 75 mg of Topamax after almost four weeks, without any real side effects. I figured I would stop at 100?? I am really tired all the time with no real motivation which has been the case for about six months now (before Topmax) Would increasing the dose help with energy or would it be more sedating? Overall I am jittery-but tired sometimes hungry sometimes not as hungry but never not been able to eat something
> >
> > I am also curious about your thoughts on time of day dosing, I take the full dose at night, but I see some people split their doese and take on during the day.
> > Sorry to be so full of questions, I was excited to get someone with your background on the board. My doctor feels like it is still "experimental" so he is hardly a resource.
> >
> > I know you are probably still busy researching, whatever your personal thoughts or theories I would love to hear about them, if you have time.
> > Thanks,
> > Kristen
> >
> >
> > > I am a researcher and have been researching topamax for about 6-7 years. Topamax interferes with estrogen-type birth control. So I would back it up with condom usage, or stronger BC. Also, depression is side effect of topamax. Topamax works on the gaba receptors in the temporal lobe. Great for mania side of bipolar, but does nothing, if not exacerbate depression and anxiety. An anti-depressant is the usual protocol add-on for topamax. Or another MS which works on depression, such as lamicatal. Regards. Murph.
> > >
> > >
> > > > Hi, this is my first post, but I've been lurking for a while. My doc currently has me on 75mg Topamax for: compulsive eating, as a mood stabilizer, and for some OCD tendencies; and 20mg Lexapro for depression and anxiety. I have a side effect from the Topamax I haven't heard anyone else mention. I began getting a feeling about it, and then I read in the accompanying literature that it can interfere with birth control pills. Anything else that does this (like antibiotics) messes up my whole cycle (sorry guys) causing much pain and a worse than ever wave of depression (this is because of female problems I've had since I was young). I was just wondering if anyone else has had this interruption in their BCP's and if stronger one's may be the answer. I was also wondering if anyone even knew about it since my doc didn't tell me!
> > > > I have also been experiencing extreme anxiety, and mounting depression ever since I've started my new regimen a month ago. I've been on the SSRI merry-go-round before, so I know it takes time, and things have been extremely crappy in my life lately, so I can't blame it all on the meds. I've definitely been through some rougher spells in the last few months than I have in years, which was why I changed my meds in the first place. But its gets really hard to tell sometimes if the pills are working like they're supposed to, or if you've waited long enough and its time to give up and try something else. I hate this wait and see part of it. Anyway, this is kind of half 'Psycho-Babble' and half 'Psychological Babble', so I didn't know where to put it. Hope it wasn't too long.
> > >
> > >
> >
> >
>
>
Posted by Murphia on November 11, 2003, at 15:07:29
In reply to re: the benefits of topamax » Murphia, posted by kka on November 11, 2003, at 14:50:05
Why are you and your husband taking topamax? What is it being prescribed for?
Yes, topamax and depakote get along pretty well together and are frequently prescribed together. However, depakote and topamax work on different parts of the brain, so depending on why he is taking these, it may not be good to decrease the depakote. Depakote should be tapered off gradually.
> Thanks for being so helpful!!
>
> Do you think I could drop (slowly) the Effexor and just take Topamax and wellbutrin? I think the Effexor makes me jittery.
>
> Also my husband has added Topamax to Paxil and 500 mgs of Depakote which is also an anti-conv. Can Topamax and Depakote be taken together if not can Depakote be stopped cold turkey?
>
> For the hair loss on Topamx, what vit. would counteract this.
>
> Just out of curiousity, in the Ortho study, didn't they give the subjects very small does at first and added mgs very slowly? This I have found has completely eliminated the s/e? I can't believe the s/e were so bad to call it off.
>
> Thanks again
> J&J (Ortho McNeill) says in their press releases they are reformulating a more "user-friendly" topa. That could be - but I would not hold my breath. Ortho had really hoped topa would be their cash cow, but it has failed miserably all the FDA and clinical trials, and now is only approved as an anticonvulsant, with nasty side efffects. Off label use has not shown to be as effective as they hoped it would be due to the s/es. Weight loss is a random side effect, not everyone experiences it, however, it is a nice bonus if it helps your other symptoms.
> >
> > Max therapeutic dosage of topa is recommended to be 400 mg., but I have talked to people that have been up to 600 mg, so you can go higher. Topa has actually shown to be very effective for binge eating and instrusive thought disorders, so it just may help you. As far as time of day, many people play with splitting their dose, or taking all at night if the s/es for them are bad. Topamax can be very sedating, and once again, that's kind an individual thing. For me it is, so I take mine at night. I have corresponded with a few people that say it makes them jittery, so they take it in the morning. Many people split half and half morning and night. Topa's half life really lends itself more effective at taking twice a day.
> >
> > Topa doesn't seem to have any adverse effect on long term use, except for maybe hair loss, which becoming quite a frequent complaint. Topa really doesn't do much for depression though, so you want to watch that, and get a stronger AD if warranted.
> > You also want to keep watch your eyes, kidneys, urinary tract, drink tons of fluids and take a lot of vits, because topa robs your body of a lot of vits. Hope this helps.
> >
> > > Murph,
> > > Is Johnson and Johnson really reformulating the drug, if so how far along are they? Have you found any weight loss at 100mgs. Is is safer to increase past 100mgs for weight loss reasons alone? How about long term use?
> > >
> > > I am hoping Topamax is the drug for me. I am begining to think I really have mild ocd along with binge or over-eating to cover emotions. I keep getting diagnosed for depression/anxiety but I feel the extra 20 lbs is really the cause of the depression. I am currently on Effexor 75 mgs, 150 wellbutrin and have reached 75 mg of Topamax after almost four weeks, without any real side effects. I figured I would stop at 100?? I am really tired all the time with no real motivation which has been the case for about six months now (before Topmax) Would increasing the dose help with energy or would it be more sedating? Overall I am jittery-but tired sometimes hungry sometimes not as hungry but never not been able to eat something
> > >
> > > I am also curious about your thoughts on time of day dosing, I take the full dose at night, but I see some people split their doese and take on during the day.
> > > Sorry to be so full of questions, I was excited to get someone with your background on the board. My doctor feels like it is still "experimental" so he is hardly a resource.
> > >
> > > I know you are probably still busy researching, whatever your personal thoughts or theories I would love to hear about them, if you have time.
> > > Thanks,
> > > Kristen
> > >
> > >
> > > > I am a researcher and have been researching topamax for about 6-7 years. Topamax interferes with estrogen-type birth control. So I would back it up with condom usage, or stronger BC. Also, depression is side effect of topamax. Topamax works on the gaba receptors in the temporal lobe. Great for mania side of bipolar, but does nothing, if not exacerbate depression and anxiety. An anti-depressant is the usual protocol add-on for topamax. Or another MS which works on depression, such as lamicatal. Regards. Murph.
> > > >
> > > >
> > > > > Hi, this is my first post, but I've been lurking for a while. My doc currently has me on 75mg Topamax for: compulsive eating, as a mood stabilizer, and for some OCD tendencies; and 20mg Lexapro for depression and anxiety. I have a side effect from the Topamax I haven't heard anyone else mention. I began getting a feeling about it, and then I read in the accompanying literature that it can interfere with birth control pills. Anything else that does this (like antibiotics) messes up my whole cycle (sorry guys) causing much pain and a worse than ever wave of depression (this is because of female problems I've had since I was young). I was just wondering if anyone else has had this interruption in their BCP's and if stronger one's may be the answer. I was also wondering if anyone even knew about it since my doc didn't tell me!
> > > > > I have also been experiencing extreme anxiety, and mounting depression ever since I've started my new regimen a month ago. I've been on the SSRI merry-go-round before, so I know it takes time, and things have been extremely crappy in my life lately, so I can't blame it all on the meds. I've definitely been through some rougher spells in the last few months than I have in years, which was why I changed my meds in the first place. But its gets really hard to tell sometimes if the pills are working like they're supposed to, or if you've waited long enough and its time to give up and try something else. I hate this wait and see part of it. Anyway, this is kind of half 'Psycho-Babble' and half 'Psychological Babble', so I didn't know where to put it. Hope it wasn't too long.
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Posted by Shirlee on November 11, 2003, at 15:14:23
In reply to Topamax Experiences?, posted by Kingfish on January 4, 2001, at 7:29:48
I am taking topamax for post-herpetic pain due to shingles that has lasted for over a year. Also for Essential tremor. I have gradually worked up to 100mg over a period of 3 weeks. I write a weekly column for a newspaper. I would like to continue this if I can stay awake. Some of you have led me to beleive this too may pass. I have been on this dosage for about 2 weeks. I don't think it's doing anything except...zzzzzzz
Posted by TexasChic on November 11, 2003, at 15:15:20
In reply to Re: Dumb Question about Topomax » TexasChic, posted by headachequeen on November 11, 2003, at 14:37:05
Yeah, if anyone knew how many times we've had to patiently wait, while physically suffering in torment, and inside we feel as if we're silently going insane...
...just to try out the latest med.
Posted by kka on November 11, 2003, at 15:35:18
In reply to re: the benefits of topamax, posted by Murphia on November 11, 2003, at 15:07:29
He is taking for cronic daily headaches/migrains (Depakote doesn't work as good as it use to) weight control from Paxil and Depaoke and I am hoping it will help with some tendences with alcohol.
Me, mild ocd, anxiety and over-eating and eating when not hungry, gained 20 lbs on A-D's.
Posted by kka on November 11, 2003, at 15:39:31
In reply to re: the benefits of topamax, posted by Murphia on November 11, 2003, at 15:07:29
Oh I forgot he is on Strattera for ADHD and the paxil is for GAD
Posted by Murphia on November 11, 2003, at 15:55:03
In reply to re: the benefits of topamax » Murphia, posted by kka on November 11, 2003, at 15:39:31
Well, depakote kind of hits the whole brain, topamax only hits the temporal lobe. If you have a temporal lobe issues, topamax is going to help you. That is why your husband should taper off the depakote gradually, because topa is not necessarily picking up where it leaves off. I think strattera is one of the best things to come around in a long time. Strattera converts L-DOPA to norepinephrine and still reuptakes some dopamine in the process, which makes it a very good all around brain med, in my opinion, and also good for depression.
Give topa a try, it may work for the both of you. Titrate very slowly (somehow I think you know that), take all your vits, and heavy on the biotin.
> Oh I forgot he is on Strattera for ADHD and the paxil is for GAD
Posted by Nervz on November 11, 2003, at 15:57:36
In reply to re: the benefits of topamax » Murphia, posted by kka on November 11, 2003, at 15:39:31
Hi, I've had a prescription for 100mg of Topa for over a month and I'm too scared to take it. 100 mg seems like a lot to start with. Does anyone know if I can cut it in half? I'm taking it for weight gain from Prozac. Thanks -- Nervz
Posted by Murphia on November 11, 2003, at 16:02:17
In reply to re: the benefits of topamax, posted by Nervz on November 11, 2003, at 15:57:36
I have only ever talked to one person that started at 100mg, and they did have some side effects. Most people ususally start at 15 or 25 mg. and work their way up very slowly. Very slowly. Topa's s/es can actually not be bad if you go slow. Yes, you can cut them, but why don't you just have your doc redo your script for 15 or 25 mg. That way, when you do increase your dosage, it will be easy for you to adjust your med.
> Hi, I've had a prescription for 100mg of Topa for over a month and I'm too scared to take it. 100 mg seems like a lot to start with. Does anyone know if I can cut it in half? I'm taking it for weight gain from Prozac. Thanks -- Nervz
>
Posted by kka on November 11, 2003, at 16:35:07
In reply to re: the benefits of topamax, posted by Murphia on November 11, 2003, at 15:55:03
Interesting about Strattera, I have been reading a lot about it lately - I need to change my dr. and I am going to request Strattera (I think it would add energy), If I added it to Topamax, do you think I would still want to take wellbutrin. I think I am just hanging on to the Wellbutrin for weight loss reasons, my dose is so low -150mg that I haven't really lost weight. Would I keep it?
Also, Why do they mostly market Strattera to children, and not as a AD for adults I know that it is a non-stimulat way to increase concentration, I sure this is a much better medication for kids. But you don't hear it advertised as an AD for Adults. AS you mentioned it seems like a pretty good new drug.
BTW- what would be some temporal lobe issues?
Posted by Murphia on November 11, 2003, at 16:54:03
In reply to re: the benefits of topamax » Murphia, posted by kka on November 11, 2003, at 16:35:07
Temporal lobe issues could be anger, kindling and/or epilepsy, mania, intrusive thoughts. But they are not always. Sometime these things come from the temporal lobe, sometimes not.
It is not good to take wellbutrin and strattera together. The problem with taking both is they pull from the same starting source in the brain. Both pull from L-DOPA which is the start of dopamine in the brain. Wellburtrin continues down the dopamine neuron path while strattera converts L-DOPA to norepinephrine and still reuptakes some dopamine in the process.
If you took strattera and it worked there is a good chance you would not need wellbutrin. The problem with taking both is they are both fighting for the same source and when you do that you run the risk of having one of the meds not work correctly because your body only produces so much dopamine.
IF you felt you needed the wellbutrin and you wanted to give the strattera a try you could lower down your wellbutrin dose and start the strattera.
> Interesting about Strattera, I have been reading a lot about it lately - I need to change my dr. and I am going to request Strattera (I think it would add energy), If I added it to Topamax, do you think I would still want to take wellbutrin. I think I am just hanging on to the Wellbutrin for weight loss reasons, my dose is so low -150mg that I haven't really lost weight. Would I keep it?
>
> Also, Why do they mostly market Strattera to children, and not as a AD for adults I know that it is a non-stimulat way to increase concentration, I sure this is a much better medication for kids. But you don't hear it advertised as an AD for Adults. AS you mentioned it seems like a pretty good new drug.
>
> BTW- what would be some temporal lobe issues?
Posted by Nervz on November 11, 2003, at 18:12:10
In reply to re: the benefits of topamax, posted by Murphia on November 11, 2003, at 16:02:17
Thanks so much for the advice. When you say build up slowly, exactly what do you mean? If my pdoc writes me a scrip for 25 mg. Do you think that upping it every week is slow enough? Thanks again-- nervz
Posted by Sabina on November 11, 2003, at 19:34:43
In reply to re: the benefits of topamax » Murphia, posted by Nervz on November 11, 2003, at 18:12:10
i'm confused...thought i was having deja vu there for a minute until i looked back at the history. http://www.dr-bob.org/babble/20031105/msgs/276912.html
i'm sorry you're still so "nervz"-ous about taking topamax that you need to keep asking the same questions. maybe after you keep hearing the same answers (about increasing dosage, etc.) from enough different people you'll feel confident enough to try it? good luck.
Posted by headachequeen on November 11, 2003, at 21:17:16
In reply to re: the benefits of topamax » Murphia, posted by Nervz on November 11, 2003, at 18:12:10
> Thanks so much for the advice. When you say build up slowly, exactly what do you mean? If my pdoc writes me a scrip for 25 mg. Do you think that upping it every week is slow enough? Thanks again-- nervz
my neurologist gave me a protocol (with a copy for the pharmacist ) that I was to follow as I increased the dosage over a period of weeks... I would assume that any doctor who wanted a patient to increase the dosage would give a similar direction with a time frame...
I was told how long to stay on each dosage and also told to continue at each dosage longer if I felt that I was not ready to increase the dosage...
although there was no indication of reason to stay ...
Posted by headachequeen on November 11, 2003, at 21:25:32
In reply to re: the benefits of topamax, posted by Murphia on November 11, 2003, at 15:55:03
> take all your vits, and heavy on the biotin.
>
>
I had thought of the biotin... we give it to the dogs to maintain good coat... and wondered if it should be a multivitamin or should one do a mixture of individual vitamins????
all help appreciated <g>
and may one state that one is greatly pleased to be more awake than usual this evening....
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