Psycho-Babble Withdrawal | about withdrawal from medication | Framed
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Re: Kindling?

Posted by SLS on March 6, 2005, at 8:05:21

In reply to Re: Kindling?, posted by SLS on February 22, 2005, at 16:07:47


I'm not entirely sure that kindling can account for the length of time withdrawal symptoms can persist for weeks and months after drug discontinuation. I would love for there to be a study on this. Will a taper schedule that prevents a withdrawal syndrome from appearing also prevent it from persisting? This is a question that is crucial to have answered.

An alternative explanation is that the changes in gene expression that occur during treatment persist as the altered dynamics between second messengers and nuclear events remain chronic. This would really suck. However, I would not give up on the idea that this situation could not be remedied pharmacologically. I would be interested to know how lithium might affect withdrawal. It might help reduce the excitability of the neuron by reducing the expression of G-protein coupled serotonin receptors.

Any takers?

- Scott




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Psycho-Babble Withdrawal | Framed

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