Psycho-Babble Substance Use | about substance use | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: Experiences with ecstasy during depression?

Posted by TriedEveryDrug on February 24, 2010, at 0:11:01 [reposted on February 26, 2010, at 8:54:34 | original URL]

In reply to Re: Experiences with ecstasy during depression? em_kath, posted by Economist on February 23, 2010, at 23:11:28

> I've read that taking E with an SSRI simply blocks the effect of E.

Yes, allegedly. Also:

What I have read about SSRIs and E is that taking an SSRI 6 hours or so into an E trip would block the entrance of dopamine (mistakenly) into serotonin terminal vesicles, which E leaves wide open. Dopamine getting into serotonin vesicles results in neuron damage from the H2O2 byproduct of MAO-B deamination of dopamine.

(there is a slide show kicking around the net illustrating the mechanism of neurotoxicity of mdma)

Anywho, I'm not recommending any of the above, nor do I have any experience with it.

I'd love to try MDMA, but how can you know what you're really getting? MDA, which is often in street E is definitely toxic.




Post a new follow-up

Your message only Include above post

Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.


Start a new thread

Google www
Search options and examples
[amazon] for

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Substance Use | Framed

poster:TriedEveryDrug thread:937967