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Neurobiological Consequences of Child Mistreatment

Posted by violette on September 21, 2010, at 11:14:05

Neurobiological Consequences of Different Forms of Childhood Maltreatment:

We have proposed that early childhood maltreatment acts as a severe stressor, that produces a cascade of physiological and neurohumoral responses which leads to enduring alterations in the patterns of brain development, and that alterations in brain function set the stage for the emergence of psychiatric disorders.

Regional Consequences of Early Stress:

Corpus Callosum
Prefrontal Cortex
Cerebellar Vermis
Visual Cortex
Auditory Cortex

A vast array of stimuli and experiences are likely to affect brain development throughout a host of sensitive periods that await discovery. Stress has been identified as a key experiential factor that programs and modifies brain development. We now provide the first evidence of discrete sensitive periods in which specific brain regions are uniquely susceptible to the
effects of early stress.




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