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Re: if Abilify works, what else might work? pedr

Posted by SLS on June 3, 2012, at 23:30:37

In reply to if Abilify works, what else might work?, posted by pedr on June 3, 2012, at 14:58:37

> Hi,
>
> I've dabbled with Abilify 3 or 4 times now, with different "main" AD's. Each time it makes me the healthiest and happiest I've been since my mental health hit the fan - by miles. However, each time it poops out after approx. a month.
>
> I've been trying to work out what meds are similar in profile, pharmacology, affected receptors and neurotransmitters. But I'm no pharmacist and since Abilify is a novel AD, I'm not having much luck finding alternatives for when it poops out.
>
> If anyone has any suggestions, I'm all ears.
>
> TIA, Pedr
>


I know several people who have had luck combining Abilify with Lamictal.

Add memantine (Namenda)?

A new psychotropic drug should be out soon. It is called cariprazine. It shares with Abilify the property of dopamine D2/D3 receptor partial agonism. It might be this mechanism that produces the antidepressant effects of these drugs. Cariprazine has a greater preference for D3 receptors than does Abilify, and might have a more pronounced antidepressant effect. We'll see.

I guess you could investigate full DA agonists like Mirapex and Requip.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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poster:SLS thread:1019165
URL: http://www.dr-bob.org/babble/neuro/20110604/msgs/1019201.html