Posted by DyseaseModel on April 8, 2012, at 23:29:35
In reply to Seeking insight on treatment resistant depression, posted by Amorphous on December 19, 2011, at 3:07:56
What if treatment resistant depression was actually not solvable in the brain, where symptoms appear to be depression, but result from other chronic endocrine/stress response disease?
Also, I rarely see any info on alternatives to the Standard American Diet, or food allergies... What about ameliorating our environments, and tailoring our worlds by addressing our negative circumstances?
I'm not implying it's situational-- I'm suggesting that there's more to depression (whatever the source) than neurotransmitters, and that we should buffer ourselves on all fronts. Good diet, a less stressful workplace, better relationships, exercise, traditional chinese medicine, meditation, etc...
Ideally, a longer acting AD would provide the bootstrapping needed to allow the time for CBT to help you create new associative neural habits.
Think about the HPA axis, ACTH, CRH, cortisol, oxytocin, vassopressin, testosterone, thyroid function. The Disease Model...