Psycho-Babble Neurotransmitters | advanced medication issues | Framed
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Re: agomelatine and mucuna pruriens: safe?

Posted by mtdewcmu on April 14, 2011, at 0:20:53

In reply to agomelatine and mucuna pruriens: safe?, posted by Tusco on April 12, 2011, at 14:29:51

Agomelatine apparently depends on the liver enzymes CYP1A2 and CYP2C9 for its metabolism. So that is a potential source of interactions. If anything in mucuna pruriens inhibits those enzymes, you may have your levels of ago increased, and conversely, if ago inhibits those or some other enzymes, you may overdose on something in mucuna pruriens. Agomelatine is probably not going to kill you, but something else might.




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