Psycho-Babble Neurotransmitters | advanced medication issues | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: Please explain agomelatine action on 5HT?

Posted by desolationrower on March 25, 2011, at 6:29:46

In reply to Please explain agomelatine action on 5HT?, posted by Franz on March 4, 2011, at 10:21:36

> Hello, Doc suggested switching from escitalopram 10 mg to agomelatine.
> It is very expensive so I have to evaluate it.

agomelatine seems to be bit faster working than some other drugs. the best way to know is spend a week or three with it.

> As I understand it enhances melatonin "reception" or sensitivity. When I used melatonin to sleep I had nightmares. Will this happen with agomelatine?

maybe, maybe not. the 5ht2c antagonism should decrease time spent in REM so there should be less 'dreaming' than with pure melatonin.

> The supposed (I read articles negating this) 5-HT2C receptor antagonism affects serotonin?. How does this compare to escitalopram. Can this also have an anti obsessive effect?

serotonin=5ht. ssris are blunt, whereas blocking a certain receptor is a more specific effect. this can be good or bad; it can avoid side effects, or not do the useful thing you need. I think there is some evidence on 5ht2c in OCD though most looks at 5ht2a.

> Is the structure of agomelatine similar to tianeptine?

probably just to the extent that is needed to be sorta kind like 5ht and so effect various things 5ht intereacts with.

> Thanks and sorry for all the quesations.


Better living through chemistry, socialism, and big phallic rockets (with a side of roquette)




Post a new follow-up

Your message only Include above post

Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.


Start a new thread

Google www
Search options and examples
[amazon] for

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Neurotransmitters | Framed

poster:desolationrower thread:980083