Posted by mtdewcmu on January 2, 2010, at 17:18:43
In reply to Re: 5HT Receptors, posted by Brainbeard on January 2, 2010, at 15:12:53
> > > * fluvoxamine/Luvox: stronger affinity for 5HT3-receptor, which means more initial nausea but more eventual anti-anxiety and anti-OCD (at least in theory..); most sedating of the SSRIs.
> >
> > I'm not sure what you mean by this. Do you mean that Luvox directly interacts with the 5-HT3 receptor? Or that somehow it interacts more strongly with the 5-HT transporter at synapses with 5-HT3 receptors?
> >
>
> I'm not sure either; I think the latter.
>Maybe it tends to stay in the body rather than accumulating in the brain, and therefore attacks the gut. Prozac is the opposite; brain concentrations wind up much higher than concentrations in the blood.
poster:mtdewcmu
thread:896245
URL: http://www.dr-bob.org/babble/neuro/20091104/msgs/932164.html