Posted by Brainbeard on September 12, 2009, at 6:45:14
In reply to Re: The Final Pathway To The Dopaminergic Pot Of G, posted by metafunj on September 12, 2009, at 2:03:05
Buspirone only temporarily decreases serotonin levels; they return back to normal within a couple of hours. So that probably couldn't provide a steady solution if your analysis is right.
Remeron appears to be very sedating to most, not to mention its weight gain. I feel that sedation is likely to ruin the benefits of 5HT2A/C-antagonism.
Cyproheptadine is an interesting drug, but also very antihistaminergic=sedative. Seems like a bit of a horse med, as we say in Holland.
Your best bet may be the Prozac + buspirone. Personally, I do feel that stimulating drugs might help your symptoms. They can at least provide motivation and initiative, and perhaps make you happier as well.
Unfortunately, stimulating meds usually have an anxiogenic effect on me. I sometimes feel biochemically stuck between lust for life + anxiety or lack of anxiety + apathy. I know I'm not the only one.
It's too bad that pure 5HT2A/C-antagonists haven't found their way onto the market. It seems that they didn't do too well as antidepressants in the trials.