Posted by SLS on February 12, 2009, at 7:07:00
In reply to Re: Why do SSRIs SNRIs affect libido?, posted by SLS on February 12, 2009, at 7:02:01
> SRIs flood the synapse with serotonin, which bathes the 5-HT2c receptors and stimulates them to inhibit libido. Nefazodone blocks these receptors from stimulation by serotonin, and thus allows the libido to rise.
I guess I should mention that things don't look quite that simple as dopamine depletion has been a theory floating around for a number of years. Perhaps this is why, with some people, Wellbutrin or Ritalin can help while taking a SRI.
A drug called cyproheptadine (Periactin) is sometimes used just before intimacy to promote sexuality and orgasm. It is a potent 5-HT2c blocker.