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Re: what is erythropoietin? » linkadge

Posted by Larry Hoover on May 7, 2006, at 11:44:00

In reply to Re: what is erythropoietin?, posted by linkadge on May 6, 2006, at 19:54:22

> I've been compiling a list of agents with neurotrophic potential. This one seemed to come as having ability to promote neurogenesis.

Oh? How so?

> Hmm. Created by the kidneys.
>
> Linkadge

The kidneys regulate all the osmotic gradients in plasma, somehow "integrate" some absolute density value for certain blood cells, are intimately involved in blood pressure regulation. And they send "feedback" information to distant tissues, via modulatory molecules such as this glycoprotein. If you think about it, the kidneys are constantly sending out purchase orders for some number of erythrocytes, to be delivered in two weeks time. There is a statistical likelihood that any individual molecule of this glycoprotein will bind with a distant receptor, so that blood concentration of this modulator is a direct and highly correlated measure of the demand for new erythrocytes.

How does this process influence neurogenesis?

Lar

 

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poster:Larry Hoover thread:640545
URL: http://www.dr-bob.org/babble/alter/20060428/msgs/640936.html