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creatine/methylation,B12, Folate, sulfation, CoQ10 » raybakes

Posted by tealady on October 15, 2004, at 19:19:05

In reply to Re: brain fog and creatine/methylation » Larry Hoover, posted by raybakes on October 15, 2004, at 12:55:36

Hi Ray,

I haven't tried the methylation bit as yet.
What type of betaine do you take? I'll have to put an o'seas order in soon from somewhere as I've run out of P5P B6.
Only betaine I can get in Oz is Betaine HCL.
I used to take B12 as my blood levels were low..both needle form (hydroxycobalamin..the only type available in Oz besides cyanocobalamin)

>sublingual B12, folinic acid and betaine
>
What is folinic acid..I gather some kind of folate...or why is it preferable to you?. I do take extra folate in addition to what's in my multi.Mine is called folic acid 550mcg. Its an oil based capsule. It doesn't appear to have much affect, then again it doesn't hurt. My folate blood levels before any supps were ABOVE range though...and so were my Mum's.
I ended up taking the additional folate as Lar mentioned something about falsely high blood levels maybe, but he couldn't remember the details I think.
Both my Mum's and my blood levels of B12 were low, and both had folate above range..Her B12 was lower than mine and folate higher...almost like our bodies try to replace the low B12 with folate?
I do notice my Mum has a far better memory after B12 needles (hydroxycobalamin), but she hasn't had any for a while. Before the needles it was difficult to hold conversation with her. So I'm pretty sure B12 can help with Alzheimer's type symptoms at least for some.
I couldn't get a homocysteine test. (local GP told me "homocysteine doesn't exist in Australia"..his exact words <g>)

On B12 and me...I stopped taking it last February? My blood levels were fairly good then.
The reason I stopped taking it was I always had strange reactions to B12 needles, and to a lesser extent the methylcobalamin sublinguals. I've got some old posts on here about this I'll try to find as my memory is poor.


CoQ10..yeah I always knew about the oil based type being the only type to take. Maybe in Oz we are ahead in something!<g>
I took it religiously for a year but stopped a couple of weeks ago when I read something...it was probably that low oxygen connection thing you mentioned. Initially I think the CoQ10 really helped me as my gums used to bleed a lot despite VitC which did help a bit. My gums stopped bleeding, went a lot pinker and healthier looking....blaming the mercury here! And I think it helped with the energy too.
I've lost a lot of hair and my skin etc has wrinkled a lot in the past year though..looks like I've aged 20 years!
Partly this is to do with loss of excess weight..but I didn't have wrinkles before I blew up! So I'm concerned if any supps are speeding up the aging bit probably via low oxygen and oxidation..I get lost with this stuff still!
So after reading whatever it was about CoQ10 I stopped taking it and I think I improved. Can't really tell I guess.
Maybe one only needs to get it to a certain level or maybe I needed more of other nutrients for balance, but I'm not taking it again..,,at least until my gums start bleeding I think. At least I know its something I need then. and will help me.
Wish I could remember what is was I read too, maybe it was from you? *grins*


> Creatine in some abstracts, has been found to protect dopamine and tyrosine hyroxylase too.

Interesting. Both dopamine and tyrosine hydroxalase with me appear to need a bit of a hand(I think). I thought it might be the P5P B6 here.

>
> Do you know if the sulphation of dopamine is important in dopamine transport/storage? Just seen a few references to free dopamine acting as an oxidant?

Gee I really get lost trying to work out sulphation. I have an article on it I tried to work thru
http://edrv.endojournals.org/cgi/content/abstract/23/5/703
..but I figure maybe another year or two of study first! I suspect you are onto something here though.
I'm got interested as thyroid hormones also have a T3S ..no idea if any free part is measured when in the Ft3 levels or not.
Very confusing.
Also on allergy tests and elimination diets and retrials I am sensitive to sulphur preservatives. Maybe sensitive to sulphur based drugs too..at least I get nausea and feel dreadful after a few days, so I avoid them.
Because of this I've avoided any sulfate form of supps. Last month I did have a zinc sulfate (one capule..50 mg of zinc sulphate monohydrate) and soon after ended up vomiting, sweating ,shakin for about 30 mins or maybe an hour? Then I was OK. Any thoughts on this?
>
> Thanks,
Jan


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poster:tealady thread:402926
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