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Re: Wash out selegiline before 5HTP? » btnd

Posted by Emme on January 3, 2004, at 0:01:14

In reply to Re: Wash out selegiline before 5HTP? » Emme, posted by btnd on January 2, 2004, at 19:07:42

Can you post the reference for the article? I'd like to get a copy to give to my pdoc.

Thanks,
Emme

> No need to. Check out this article:
>
> "In 1978 Mendelwicz and Youdim treated 14 depressed patients with 5 mg deprenyl plus 300 mg 5-HTP 3 times daily for 32 days. (1) Deprenyl potentiated the antidepressant effect of 5-HTP in 10/14 patients. 5-HTP enhances brain serotonin metabolism, which is frequently a problem in depression (37), while deprenyl enhances dopamine/noradrenalin activity. Under-activity of brain dopamine, noradrenalin and serotonin neural systems are the most frequently cited biochemical causes of depression (18,19,37), so deprenyl plus 5-HTP would seem a natural antidepressant combination. "

 

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poster:Emme thread:293899
URL: http://www.dr-bob.org/babble/alter/20031218/msgs/295936.html