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Re: lithium does contribute to serotonin syndrome » McPac

Posted by Larry Hoover on November 16, 2003, at 9:56:52

In reply to Re: Larry,, posted by McPac on November 15, 2003, at 14:11:39

> "Lithium doesn't cause serotonin syndrome"
>
> >>>>>>>>>> Lar, this is what I was referring to re: lithium (saw this in one of your posts last week on serotonin syndrome):
>
> "The drugs which we know most frequently contribute to this condition are the combining of MAOIs with Prozac (this should also include the other SSRIs) or other drugs that have a powerful effect upon serotonin, ie, clomipramine (Anafranil), trazadone (Deseryl), etc. The combination of lithium with these selective serotonergic agents has been implicated in enhancing the serotonin syndrome. The tricyclic antidepressants, lithium, MAOIs, SSRIs, ECT (electric shock treatment), tryptophan, and the serotonin agonists (fenfluramine) all enhance serotonin neurotransmission and can contribute to this syndrome. Anything which will raise the level of serotonin can bring on this hyperserotonergic condition".

My mistake. I was wrong about the risk of serotonin syndrome when SSRIs (particularly Prozac) are combined with lithium. Thanks for catching that....


Lar

 

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URL: http://www.dr-bob.org/babble/alter/20031104/msgs/280247.html