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Re: methylphenidate gman22

Posted by SLS on September 13, 2023, at 20:16:00

In reply to methylphenidate, posted by gman22 on September 13, 2023, at 18:19:20

> PubMed has several studies showing that for some, methylphenidate monotherapy has produced remission in treatment-resistant subjects.
> Also, patient reviews on several sites have many positive anecdotes.
> I think for me though, it's more effective as an add-on.

Whatever works.

I need lithium in my treatment regime to produce a stable, robust antidepressant response. My baseline depression is extremely anergic, with significant memory and cognitive impairments. My thoughts are slowed, and I am numb to my surroundings. I also have intrusive thoughts and negative feelings. The thing is, I require 150 mg/day of lithium for my treatment regime to work. A dosage of 300 mg/day or higher reverses the benefit, and I feel as if I relapsed. Remission does not happen for me at 300 mg/day.

About 20 years ago, Harvard conducted a study of the addition of low-dosage (300-600 mg/day) of lithium added to Prozac. They reported a statistically significant increase in response rate. However, the other treatment arm showed that increasing the dosage of Prozac to 60 mg/day rather than adding lithium produced a greater response rate.

- Scott

Some see things as they are and ask why.
I dream of things that never were and ask why not.

The only thing necessary for the triumph of evil is that good men do nothing.




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