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Re: Does anyone still take aripiprazole (Abilify)? SLS

Posted by undopaminergic on July 7, 2023, at 10:41:17

In reply to Re: Does anyone still take aripiprazole (Abilify)?, posted by SLS on July 6, 2023, at 12:09:47

>
> I am under the impression that amisulpride was used to treat depression and dysthymia at low dosages only. 25-50 mg/day, if I remember correctly.
>
>
> - Scott

Yes, there is a concern that at higher doses, it might block too many post-synaptic dopamine D2-receptors, which could counteract the desired effect of blocking pre-synaptic receptors (autoreceptors) which enhances dopamine release.

-undopaminergic


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