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Re: Reversing wrong-way brain signals Jay2112

Posted by Hugh on May 31, 2023, at 0:11:04

In reply to Re: Reversing wrong-way brain signals, posted by Jay2112 on May 26, 2023, at 20:09:08

In addition to risking serotonin syndrome by combining antidepressants with psychedelics, there's another good reason for not combining the two -- antidepressants are likely to blunt the effects of psychedelics. People might have to be off antidepressants for months to restore serotonin receptors, which become downregulated on antidepressants, so that psychedelics can have their full effect.

https://www.psychedelicpassage.com/psilocybin-blunting-effects-of-ssris-and-antidepressants/

https://www.psypost.org/2021/03/previous-antidepressant-use-may-blunt-the-effectiveness-of-mdma-assisted-psychotherapy-for-ptsd-59934


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