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Re: Antidepressants to combine with Effexor?

Posted by SLS on April 15, 2023, at 15:49:14

In reply to Re: Antidepressants to combine with Effexor? SLS, posted by Roslynn on April 15, 2023, at 12:02:36

Hi, Roslynn.

> > There are quite a few people who need 300 mg/day of Effexor. I'm one of them. 225 mg/day was insufficient.
> I've taken up to 300 in the past, actually combined with remeron, and it didn't do anything...
> >
> I am not currently on Wellbutrin, it gave me EPS.

Wellbutrin gave you EPS? What were the EPS symptoms you experienced with Wellbutrin? I have never heard of this occurring with Wellbutrin. Perhaps others have. It's a critically important question. Using Wellbutrin by itself is not the best antidepressant. It does work, though. However, the true worth of Wellbutrin is that it augments serotonin reuptake inhibitors. It works well with Zoloft, Effexor, and Pristiq.

> >
> Lamotrigine gives me major cognitive problems even at the lowest dose.
> >
> > I forgot to ask - Did lithium help at all?
> >
> Yes, it did, it was hard to see what it was doing but when I went off it, it was hell.

You came off of lithium for kidney abnormalities? What about thyroid?

What dosage of lithium worked best for you? It affected your kidneys? How was this ascertained, creatinine?

> I couldn't tolerate nardil due to major dizziness at the lowest doses.

I always experienced dizziness with Nardil over the course of 40 years. This time, I played a hunch. I thought that if I could prevent the *triggering* of side effects, perhaps they would never emerge in the first place. I began at 7.5 mg/day (1/2 tablet) for a week and increased the dosage very gradually afterwards.

7.5 mg/day = 1 week
15 mg/day = 1 week
30 mg/day = 2 weeks
45 mg/day = 3 weeks
60 mg/day = 6 weeks
75 mg/day = 6 weeks
90 mg/day = Maximum

Most people respond to 60-75 mg/day

> I don't really have discrete episodes of depression--just one continuous one for many years.

Didn't you respond well to Nardil for an extended period of time?

- Scott

Some see things as they are and ask why.
I dream of things that never were and ask why not.

The only thing necessary for the triumph of evil is that good men do nothing.




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