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Re: Is there any evidence that Trazodone curbs OCD? Lamdage22

Posted by SLS on January 28, 2023, at 20:00:00

In reply to Re: Is there any evidence that Trazodone curbs OCD?, posted by Lamdage22 on January 27, 2023, at 15:26:04


I don't know about trazodone. I never heard of it being used for OCD. One thing I don't like about trazodone is that it is metabolized into m-Chlorophenylpiperazine (mCPP). Do a search on Google or PubMed about it. The reports regarding mCPP and its making OCD worse are inconsistent, but it would be a concern of mine. mCPP is usually reported to provoke or exacerbate anxiety. It also increases the plasma concentrations of cortisol and prolactin. Elevated prolactin is associated with decreased levels of testosterone. However, cause and effect remains unclear.

mCPP is a serotonin receptor agonist.

- Scott

Some see things as they are and ask why.
I dream of things that never were and ask why not.

The only thing necessary for the triumph of evil is that good men do nothing.




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