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Re: Lithium biochemistry (low level mechanisms) undopaminergic

Posted by SLS on January 24, 2023, at 21:05:32

In reply to Lithium biochemistry (low level mechanisms), posted by undopaminergic on January 24, 2023, at 11:50:25

Hi, UD.

> Note: no clinically applicable information.

My concern with the posting behavior on PB isn't that all posts should be clinically applicable. My concern is that there aren't nearly enough. Pure neuroscience research is extraordinarily valuable, but more so for those who will come after us. Can someone use what they learn from research papers to design a treatment? Of, course they can. Unfortunately, this is uncommon.

Another thing that concerns me is that people obtain the right tools, but have no idea how to use them correctly.

This has been on my mind for awhile as a treatment for depression:

1. Wellbutrin
2. Nortriptyline (or another tricyclic)
3. Effexor (or Pristiq or Cymbalta)

4. Low-Dosage Lithium ?
5. Lamictal? (Bipolar Depression) ?

This should be a killer combination according to my blackboard, but how does anyone know if it will work in real life? I don't know. I personally have never seen anyone use it, though. That's clinical. Clinical is more empirical than it is theoretical. Not only does a psychiatrist learn from his own track record, but he also learns from the track records of his buddies.

Psychiatry is guess-work.

- Scott

Some see things as they are and ask why.
I dream of things that never were and ask why not.

The only thing necessary for the triumph of evil is that good men do nothing.




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