Psycho-Babble Medication | about biological treatments | Framed
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Re: Is there any evidence that Trazodone curbs OCD?

Posted by undopaminergic on January 20, 2023, at 11:05:28

In reply to Re: Is there any evidence that Trazodone curbs OCD? Lamdage22, posted by Jay2112 on January 19, 2023, at 21:27:59

> > Can anyone interpret the evidence? From what I can tell, it doesnt help much.
> No, not really. It was the 'med from hell' for me, BUT, I LOVED it's sister drug, nefadozone!! The most UNHARSH antidepressant. Marketed as Serzone in N.America. Don't know about it's effect on OCD, but it has calming effects via 5ht2a blockade.
> Jay

It seems it is actually an *agonist* at the serotonin 5-HT2C receptor:

That would translate to an antidopaminergic effect.





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