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Re: Bipolar and constipation p.s. undopaminergic

Posted by SLS on January 3, 2023, at 13:07:21

In reply to Re: Bipolar and constipation p.s. SLS, posted by undopaminergic on January 3, 2023, at 11:18:03

> > Interestingly, caffeine pills were not as helpful as coffee, even when I took a fraction of a pill. I think the pills contained 100 mg/day. Does that sound right?
> >
> Yes, in fact I've never seen a caffeine pill that wasn't 100 mg of the active principle.
> > I had to meter my intake of coffee carefully. Just a small amount - 1/4 a cup - worked wonders. Anything over that left me in a state of fatigue and brain-fog that would last all day.
> >
> I've had paradoxical sedative effects of caffeine, especially at higher doses.
> As I mentioned in another post (vortioxetine plus caffeine), I need another substance, typically a dopaminergic stimulant, in combination, to allow the caffeine to have a stimulant effect, but apparently vortoxetine can work too.
> -undopaminergic

Did aripiprazole (Abilify) help at all?

Abilify, like other D2 antagonists, increases That might add an increase in dopamine release, but mostly at low dosages.

This is what I remember to be guideline for:

2-5 mg/day for depression - presynaptic receptor blockade + Postsynaptic receptor blockade.
10-20 mg/day for bipolar mania.
20-30 mg/day for schizophrenia, schizoaffective disorder, psychosis.

- Scott

Some see things as they are and ask why.
I dream of things that never were and ask why not.

The only thing necessary for the triumph of evil is that good men do nothing.




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