Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: Tentative remission on ketamine

Posted by undopaminergic on December 31, 2022, at 14:03:45

In reply to Re: Tentative remission on ketamine, posted by Jay2112 on December 30, 2022, at 15:37:31

> Interesting....there is some new research discussing how the dissociative affects of ketamine, which bring it's therapeutic effects, as well as THC, are those we find in Scizophrenia. I find that too, with mid-dose THC, I get a fairly high dissociative feeling going. Dissociation is not always figured with Scizophrenia, but new studies are showing different: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964156/
>
> I'd take a stab at possible high dopamine levels with something like high GABA levels as well, play a part in this. The serotonin and GABA, along with norepinephrine and dopamine, are said to be increased much by Nardil, in particular, GABA.
>
> Jay

In my view, NMDA-glutamatergic receptor antagonists, like ketamine or memantine, enhance the *functional* dopaminergic tone, without necessarily elevating dopamine concentrations at all. They achieve stimulant-like or even manic-like effects by a mechanism of action that is distinct from the way stimulants like cocaine or Ritalin do.

-undopaminergic


Share
Tweet  

Thread

 

Post a new follow-up

Your message only Include above post


Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.

 

Start a new thread

 
Google
dr-bob.org www
Search options and examples
[amazon] for
in

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:undopaminergic thread:1121402
URL: http://www.dr-bob.org/babble/20220917/msgs/1121432.html