Psycho-Babble Medication | about biological treatments | Framed
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Re: To Linkadge....

Posted by jay2112 on November 30, 2022, at 15:01:14

In reply to Re: To Linkadge...., posted by linkadge on November 29, 2022, at 15:54:25

> >How about tryptophan with choline, and/or tyrosine? >(In combination?) And GABA?
> Actually, GABA does help me. It seems to help with GI issues, sleep. If I take it too many nights in a row, there is some depression, however.
> Interestingly, GABA supplementation can significantly increase gut butyrate production. Butyrate (like valproate) is an HDAC inhibitor with mood stabilizing properties. Although GABA doesn't pass the BBB too well, butyrate does. Gaba is also helpful for my cardiac anxiety. GABA circulates peripherally and can slow heart rate and blood pressure.

Hmmm...interesting. A GABA analogue, pregabalin, helps me in a similar way. I too am having severe problems with drive and motivation. I am now combining a higher dose of carbamazapine and 225mg's of venlafaxine. I am lucky that my pdoc is keeping me on clonazapam. I *don't* know if this is going to cause major akathisia or/and profuse sweating and anxiety. I hope the carbamazapine offsets that, as it seems to have in the past.

Like you, I have an on/off relationship with venlafaxine. All's we can do is try, right? IF it doesn't work out, I may go with moclobemide. The thing is, moclobemide doesn't do much for my anxiety, and in fact, boots it up a notch, just like Effexor. The only thing is, moclobemide doesn't have as much of the "cheese" effect as the traditional MAOI's.

So....I wish us both luck... :)


Humans punish themselves endlessly
for not being what they believe they should be.
-Don Miguel Ruiz-




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