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Re: substitute for lithium? Roslynn

Posted by SLS on May 24, 2022, at 23:17:58

In reply to substitute for lithium?, posted by Roslynn on May 20, 2022, at 14:39:21

> Hi all,
> I had to stop lithium due to kidney problems. I was taking it to augment my other depression meds (not for mania).
> So far, I haven't been able to find a decent replacement. I'm on Latuda but it doesn't seem to be helping. Lamictal gives me cognitive problems. My mood is sliding down each week.
> Anyone have any thoughts or suggestions? My other meds are effexor, latuda, seroquel, ativan, and ritalin. Diagnosis is major depression, OCD, and anxiety.
> Thank you for any help!
> Roslynn

There are two things you can do that might allow you to stay on lithium.

1. Since you respond to lithium so well, you might consider trying a low-dosage strategy. Low dosages of lithium often work for depression, but not mania. At 300 mg/day, there is usually little risk of it causing nephrotoxicity. You might respond to it equally well, if not better, than treatment with a higher dosage.

2. Although the toxicity of lithium at 300 mg/day is usually minimal, you can reduce the load on the kidneys even more if you take your entire daily dose at bedtime.

- Scott

Some see things as they are and ask why.
I dream of things that never were and ask why not.

The only thing necessary for the triumph of evil is that good men do nothing.




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