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Re: substitute for lithium?

Posted by Hugh on May 23, 2022, at 11:47:49

In reply to substitute for lithium?, posted by Roslynn on May 20, 2022, at 14:39:21

The dietary supplement agmatine is an NMDA antagonist, like ketamine. Agmatine appears to have the same antidepressant and pain relieving properties as ketamine, but without its side effects.

In a pilot study that used agmatine to treat small fiber neuropathy, the study participants took 6 445-mg capsules of agmatine sulfate per day (3 capsules twice daily or 2 capsules three times daily). At the end of two months, all patients showed improvement, but to a varied extent. The average decrease in pain intensity for all 11 patients was 46.4%.

"Evidence for Dietary Agmatine Sulfate Effectiveness in Neuropathies Associated with Painful Small Fiber Neuropathy. A Pilot Open-Label Consecutive Case Series Study"




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