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Re: Why do meds constantly stop working for me?

Posted by rose45 on September 13, 2021, at 7:28:08

In reply to Re: Why do meds constantly stop working for me? rose45, posted by SLS on September 12, 2021, at 13:16:23

Hi Scott,

Im not sure why you say you are surprised that lamotrigine lasted so long for me. If you look at my last posts , it lasted just 3 months and then stopped working. It started working at 100 and there was not much change between 100 and 200mg. After 3 months at 200, it just stopped working and increasing the dose made no difference. I note it took a higher dose to work for you, but I do tend to take lower doses of all meds, than most people.

I also had to add low dose olanzapine, because without it, the lamotrigine on its own made my mind very cloudy and I did not feel like myself at all.

I hesitate to increase the dose at this point as it has severely affected my memory. I cant remember how to do the simplest tasks on the computer and this creates so much anxiety for me.

Does this make sense to you?

Do you agree that low dose antipsychotics act very differently to higher doses ? This was certainly true of olanzapine - 2.5 mg of olanzapine got the Parnate to work again. But yet again, when I reduced the olanzapine slightly, the parnate stopped working altogether.

I wonder whether the two anti-psychotics you mention would have a similar effect? I wish I could try just a small amount of them, but they are so expensive here I doubt our NHS would agree to let me have them. If you think there is any possiblity they might potentiate the parnate, I could try to obtain a small quantity privately.

I would appreciate your thoughts on this. I am still taking 2.5mg olanzapine as it does help me to sleep, but it no longer augments the parnate as it did the first time I took it.

From what others have said to me low dose olanzapine increases dopamine, or words to that effect. Aripiprazole did not have that same effect, so I dont know whether the other anti psychotics you mention could act like olanzapine as dopamine enhancers. Sorry I am not at all technical and dont understand most technical terms.





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