Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: Short-Course Zuranolone Looks Promising for MDD

Posted by SLS on June 29, 2021, at 16:07:59

In reply to Re: Short-Course Zuranolone Looks Promising for MDD, posted by linkadge on June 22, 2021, at 15:16:46

> Very cool. Nice to see some different mechanisms.
> Linkadge

I had been looking at zuranolone (SAGE-217) beginning in 2019 after the I.V. post-partum drug, brexanolone (Zulresso), was approved. Both drugs were developed by the same drug company as part of a series of related compounds. Zuranolone was the second of the series to be chosen for clinical trials. Hopefully, I will never need it. It was going to be the very next thing I would have tried had I not found success with my current treatment.

Positive allosteric modulators bind to a secondary site on a receptor such that it changes the shape of it. This makes the GABA-A receptor more sensitive to GABA.

These new drugs are related to the progesterone-like substance, allopregnanolone

- Scott

Some see things as they are and ask why.
I dream of things that never were and ask why not.

The only thing necessary for the triumph of evil is that good men do nothing.




Post a new follow-up

Your message only Include above post

Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.


Start a new thread

Google www
Search options and examples
[amazon] for

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:SLS thread:1115627