Posted by undopaminergic on June 23, 2020, at 21:32:29
In reply to Re: How does Lumateperone compare to antidepressants?, posted by linkadge on June 23, 2020, at 18:07:32
> Lumateperone is a very strong antagonist of 5-ht2a and much less potent as an antagonist at dopamine receptors.
>
> If it is combined with an SSRI, there is a very very low possibility of some degree of serotonin syndrome.
>Why's that? You say it's a very strong serotonin 5-HT2A receptor antagonist, so if anything, I would expect it to be an *antidote* to serotonin syndrome.
-undopaminergic
poster:undopaminergic
thread:1110979
URL: http://www.dr-bob.org/babble/20200511/msgs/1110995.html