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Rasagiline as an unselectiv MAOI?

Posted by undopaminergic on February 25, 2020, at 9:21:20

Hi all,

I'm interested in the potential of using rasagiline (Azilect) the same way as classic MAOIs.

Rasagiline is a selective MAO-B inhibitor in typical doses as used for Parkinson's disease, but as far as I know, it will inhibit MAO-A in sufficient doses.

It is most directly comparable to selegiline, but does not have amphetamine metabolites.

You may wonder why not use the classic MAOIs instead. Well, those MAOIs are simply not marketed where I live, but rasagiline and selegiline are readily available. (The EMSAM formulation of selegiline is also not available.)





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