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Re: CBD and THC and My Experimentation...comments? linkadge

Posted by undopaminergic on December 4, 2019, at 8:32:06

In reply to Re: CBD and THC and My Experimentation...comments?, posted by linkadge on December 2, 2019, at 15:39:07

> Many antidepressants indirectly work via a cannabinoid mechanism. The TCAs for example, require an intact endocannabanioid system in order to reduce HPA axis responsiveness. Cannabinoids also have antidepressant effects in animal models.

That is interesting. I'm currently on trimipramine (Surmontil), which seems to be the only (or one of few) antidepressants that suppress cortisol secretion at night, and allows it to rebound in the mornings. Trimipramine has been shown to normalise the circadian cortisol curve in those where it is abnormal.

> Interestingly, I also notice a mild psychedelic effect whereby I feel that something has changed in me 'spiritually' where I feel like I see a higher reality. I see my problems in a new context. I detach from them and see them like I would see somebody else's problems. When I return, I feel like my life is in a better position. Traditional meds don't do anything to enhance a spiritual recovery. For me at least (I know it sounds hokey) feeling connection to a higher reality is important for my mental health.

I'm very spiritual and have had many experiences, including visiting a parallel reality. I was quite materialistic before my psychosis in the end of 2009, after which I have evolved dramatically. When I looked at my notes from before the psychosis, it looked like they had been written by a whole other person.





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