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Re: Poll: How long have MAOIs lasted b4 poop-out? » rose45

Posted by Jedi on August 13, 2019, at 12:57:09

In reply to Re: Poll: How long have MAOIs lasted b4 poop-out?, posted by rose45 on August 12, 2019, at 15:47:41

Hi Guys,
I'm one of those people that have been on long-term Nardil. Sometimes augmented with clonazepam. Over 20 years at this point. I have had short times off for other drug trials. But Nardil has been my lifesaver.

The only time that it has pooped out on me is when I'm taking low doses of 30 mg. When this happens I will up the dosage to 60 or 75 mg and usually start feeling better within a couple of weeks. I believe this shorter recovery time is because the MAOI is already partially built up in my system. So it takes less time for the full effect to kick in once I go to the higher dosage.

I take the minimal amount necessary to maintain remission. Most of the side effects have gone away over the years. But insomnia still has to be treated. And retarded ejaculation still happens at high dosage.

When I first started Nardil, over 20 years ago, I did have a major hypomanic episode. I can't tell you how good that felt after being depressed for so long. But that is not the antidepressant effect of the drug, it is a side effect. Don't misinterpret the loss of hypomania as poop out of the drug. Funny, after that initial hypomanic episode, I have never had another one. Even when off of Nardil for 9 months, when I started up again, the hypomania never came back.

For me Nardil has been the bomb. Honestly, the medication saved my life. Of course it won't be for everybody. And there are many other options. Never, never give up. We only get one shot at this life.

Be well,
Jedi

hi timidly,
>
> I know this is an old post, but could you tell me a little bit more about restarting......was it very painful getting off the medication?
> I thought once an maoi has pooped out, it would not work again for at least a while.....
>
> Both nardil and parnate have pooped out on me and I am very ill and desperate as I really dont know what to do.
>
> Thanks


Jedi
Treatment resistant, atypical, double depression with social anxiety.
Nardil + clonazepam


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poster:Jedi thread:755424
URL: http://www.dr-bob.org/babble/20190728/msgs/1105709.html