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Re: White Mulberry (Morus Alba) - Anyone know of it?

Posted by porkpiehat on January 19, 2019, at 11:46:04

In reply to Re: White Mulberry (Morus Alba) - Anyone know of it?, posted by PeterMartin on January 19, 2019, at 3:19:52

> > How are you doing I've been wanting to get in touch with you? Still on Nardil? Any word of Marplan coming back?
> >
> >
> Hey man - I am still on Nardil at 75mg. I finally found a way to get the weight to drop. I know one of your main concerns is to avoid cognitive issues though so I don't think my cocktail (at least at the moment) would be something tolerable. I'm willing to go heavy with this at the moment to bring my weight down though in the hopes that Marplan comes back on the market soon (more on that in a sec). What I'm taking now:
>
> Nardil 75mg - Gavis/Lupin Generic - (working well enough for depression / very well for social anxiety)

you came down from 90 right? what was the effect from that? Weren't you experiencing feeling of detachment and compulsivity that I was having too? (maybe that was a different poster)
>
> Lamical 200 - Taro Generic - (Was on Teva for years until they stopped making it - took months to find another generic that worked sufficiently but Taro seem to be ok - I guess it's still helping)

THIS MIGHT HELP YOU...As I came down on the Nardil I realized a lot of the effects I was having reminded me of Lamictal side effects...memory, cognition, headaches, muscle tightness... I researched Deplin again as I had bought some recently. A lot of people that had these problems saw them go away by taking 15mgs Deplin.

FURTHER research indicated that other anticonvulsants AND metformin all reduce folate levels. That might explain why my symptoms got worse (strangely) once I started taking metformin. Also, Drinking and smoking drastically reduce them. For me, all the MAOIs, Nardil especially, ramped up these compulsive behaviors. I'm on my second day of Deplin and hope it makes a big difference.


> Seroquel 25mg - Lupin Generic - Just for sleep - been knocking me out for 10+ years, never needed more, never had a problem with it.

Personally for me strong anticholingergics create a sense of stupor or delirium the next day. This is what knocks you out with the seroquel...the AP effects don't kick in at this dose.
>
> A month ago I'd had it when I was closing in on 240lbs and called my doc. I told him I had some Topamax for a couple years back that had worked fairly well and was hoping he'd ok me trying it again. He said it was ok and called in a new script as well. I've been on that a bit over a month now:
>

So the cognitive problems from the topomax is worth the weight benefits? Did you see any improvement in feeling detached or anxiety? Trileptal was helpful in reducing the unsettled, unwelcomed feeling of being out in the world but I was useless cognitively without gobs of stimulants.

> So yea Marplan. I've talked to the rep a few times (she's fantastic). I think they're working on getting a new manufacturer approved but that requires the FDA to do a ton of additional reviews. Based on a photo I saw on Drugs.com (and a review that some lady posted there in December) I think Roche might be the company and they may be having difficulty with that (long delay). The good news is Marplan is now marketed by a company in Denmark and the US company (Val.dus) is trying to get permission to import it from them for patients in the meantime.
>

I'm on the fence about going back on Marplan...I found it somewhat less detaching and I was less compulsive than Nardil.

In dropping down on Nardil I found some interesting effects:
-Way less comulsive
-sex drive returning
-I "feel" less fat lol.
-The paranoid, unsettled feeling, neurotically doubting and internal narations of my actions have dissipated. I am less fixated on the interpersonal feuds (both real and self-created) surrounding me.

I am unsure if my brain is just now more "busy" without the hyperfocus created from NE/DA properties of the MOAIs and these anxieties are burried; OR if all these monoamines flair up some latent bipolar/psychotic stuff in my genes (bipolar dad, schizo grandmother).

my big decision is do I go back up on Nardil and use lyrica, tianeptine, etc. to offset the apathy and fear? Do I try to stay at 15-10 mgs nardil so the drugs all boost one another with lower side effects, or continue my wean off.

Today at 25 mgs tianeptine sulfate I feel pretty good. Don't have weird fear around roommate, not fracture confused depressed.


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poster:porkpiehat thread:1102834
URL: http://www.dr-bob.org/babble/20181024/msgs/1102863.html